ASD

GO:0009896 positive regulation of catabolic process (99)

GeneInput weightStandardRank
SUMO1--178
PRKCE--156
AKT10.251303
APC0.251528
TRIB2--534
CSNK1D--811
HIF1A--1008
SOX9--11045
IRS1--11052
CDKN1B--1067
UBE2V2--1207
CSNK1E0.2511225
SMAD7--1283
ADRA2A0.2511556
GSK3B--1592
IRS2--11607
RCHY1--1845
IGF10.2511993
PSMD10--2012
PTEN1.012260
GSK3A--2346
ZFP36--2405
SUMO2--2503
MTDH--2631
WNT5A--2870
AKT2--13025
STUB1--3156
TRIB1--3331
CBLB--3413
SOX17--3484
BTG2--3504
TNFAIP3--3628
RNF180--3828
FZR1--3987
VCP--4121
BARD1--14151
ANGPTL3--4155
NDFIP1--4331
FURIN--4868
GPC3--15153
IFNG--15255
PRICKLE1--15311
MDM2--5588
GTPBP1--5729
PPARA--5743
ADRA1B0.2515964
TWIST1--16128
IL1B--16220
HSPBP1--6359
MYLIP--6753
GAPDHS--6782
DNAJB2--7177
USP5--7638
FABP1--7740
SH3D19--7820
ATG14--7950
GJA10.2518195
AADAC--9310
MAPK15--9705
MLXIPL--10379
ITCH--10863
AXIN1--110905
INSR--110986
UVRAG--11418
APOC2--11692
TRIM320.25112319
ARHGEF10--12556
APOA2--12739
APOA5--113056
LRRK2--113335
EGLN2--13499
GCLC--13506
PIM2--15588
INS--119021
TNF0.25119823
PSEN1--20241
PACSIN3--20292
TAF1--20307
ADAM8--20729
APOA4--20778
BECN1--20816
ABHD5--121013
SNX1--21188
APOE0.25121310
NEDD40.25121604
GNB2L1--22873
SGSM3--22884
SUPV3L1--23153
NUB1--23472
NRD1--24048
ARNT--24282
FBXO22--24394
CPT1A--24551
PNPT1--24684
ADAM9--124801
DAB2--24837
CLU--24939
PNPLA2--25194
PLK1--25689

Network

GO:0009896

Network
Enrichment
NameDescriptionExternal IDs
SUMO1small ubiquitin-like modifier 1 Entrez:7341  Ensembl: ENSG00000116030  HGNC: 12502  HPRD: 03554 
PRKCEprotein kinase C, epsilon Entrez:5581  HPRD: 01500  HGNC: 9401  Ensembl: ENSG00000171132 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
APCadenomatous polyposis coli Entrez:324  HGNC: 583  HPRD: 01439  Ensembl: ENSG00000134982 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SUMO1small ubiquitin-like modifier 1
PRKCEprotein kinase C, epsilon
AKT1v-akt murine thymoma viral oncogene homolog 1
APCadenomatous polyposis coli
TRIB2tribbles homolog 2 (Drosophila)
Query geneGeneGene descriptionEdge score
SUMO1SUMO1small ubiquitin-like modifier 1
PRKCEPRKCEprotein kinase C, epsilon
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
APCAPCadenomatous polyposis coli
TRIB2TRIB2tribbles homolog 2 (Drosophila)

Troyanskaya Laboratory - Princeton University