ASD

GO:0051960 regulation of nervous system development (338)

GeneInput weightStandardRank
NTRK30.2514
SNAP250.2516
CNR10.25110
NTRK20.25128
MAPT0.25131
SLIT1--33
BCL11A--44
NRCAM0.25149
SOX11--66
NEUROD2--68
ARHGDIA--76
ADNP0.5191
ASIC20.251105
SOX2--1125
CDH2--130
NEUROD1--1136
GRIN1--167
SYNJ1--178
SEMA4F--179
GRM50.251196
PAFAH1B10.251208
DSCAM--220
STMN2--221
ASCL1--229
CACNA1A--1231
NLGN10.251265
MAP1B--300
AKT10.251303
DBN1--332
NF10.251333
EPHA3--346
PAX60.251355
RGS6--375
RET--1384
CDK5R1--406
SALL1--408
OLIG2--420
NREP--435
CNTN2--438
PAX2--459
CDH4--468
FOXG1--483
IL1RAPL10.251519
OMG0.251521
ZNF536--527
ACTR3--573
SLIT2--582
TCF4--610
TTC3--627
RAPGEF40.251635
RAP2A--652
POU3F2--653
CCND2--689
CHRD--697
NR2E10.251699
DISC10.251723
BDNF0.251754
NKX2-2--771
LRP6--778
HOXD3--785
DLL3--1816
DICER1--1834
SIPA1L1--893
CHRNA3--910
ATN1--1941
RHOA--973
BMP7--987
THY1--993
SOX9--11045
SYNDIG1--1073
YWHAH--1109
XRCC5--1128
ID4--1171
DCC--1193
NDEL10.2511194
UBE2V2--1207
ROBO2--11224
DLX20.2511235
EP300--11256
ACHE--1266
TSPO0.2511277
EDNRB--11322
PHOX2B--1326
LZTS1--11336
RELA--1352
LRRC4C--1354
SPAG9--1398
HDAC2--1413
ISL1--1441
SOX10--11510
AKAP5--1517
ULK1--1530
TNIK--1544
FEZ1--1554
SRCIN1--1623
FGFR3--11648
ID2--1719
RTN4--1776
YWHAG--1799
KIAA0319--1819
FOXA2--1835
GFAP--11886
ROBO1--1888
RUFY3--1922
LHX1--1926
GDF6--11929
VANGL2--1957
NRP1--1961
MT3--1972
APP--1991
IGF10.2511993
XYLT1--12006
PPP2R5B--2024
CNTN41.012038
SOX3--2042
BMPR1A--2059
DRD20.2512071
SEMA3A--2076
GHSR0.2512085
SOX21--2110
DPYSL2--2131
DLL1--2143
SHOX2--2149
STK25--2150
MBP--2234
MUSK--2237
PTEN1.012260
FOXA1--2277
MYRF--2286
NTF30.2512294
NEUROG2--2345
DLX10.2512366
NCS1--2387
CIT--2426
PVRL1--2493
WNT8B--2506
SSH2--2515
FGFR1--2550
PLXNB1--2639
LHX5--2646
ZEB1--12672
CDKL5--12680
ZHX2--2748
DRD30.2512757
TNR--2784
SMAD1--2829
INPP5J--2851
WNT5A--2870
SERPINE2--2896
ILK--2917
LPAR1--2975
MIB1--3110
NKX6-1--3174
PTK2B--3191
NPTN--3227
BMP6--3242
SLC6A40.2513328
GDF11--3345
NOTCH1--13360
NLGN31.013428
CDON--3482
LIMK1--3487
ITM2C--3488
NEUROG10.2513515
NGFR0.2513554
PCM1--13562
MET1.013618
LGALS1--3679
BMP2--13686
ZNF488--3692
NDNF--3722
NGF0.2513749
HOXA2--3750
TLX2--3823
MAG--3851
KNDC1--3908
MARK2--3933
HES5--4001
CXCR4--4014
SKIL--4016
SKI--4231
DYNLT1--4275
ARF6--4366
ITGB1--4390
DVL3--4438
DIXDC1--4469
OXTR0.514494
OTP--4497
ASPA--14515
IL6--14578
RNF6--14587
SOX8--4770
WNT3--4799
WNT3A--4844
DTX1--5135
BMP4--15180
PLXNA4--5187
VEGFC--5203
IFNG--15255
NTN1--5275
LYN--5289
LBX1--5371
KATNB1--5389
NKX6-2--5422
NKX2-50.2515490
LMX1A--5502
TLX3--5583
AGRN0.2515611
HES10.2515662
BARHL2--5697
CCDC88A--5761
FRMD7--5857
SMO0.2515864
TCF3--5880
NLGN2--6159
TGIF2--6223
CTNNB10.2516229
LINGO1--6233
WNT7A--6375
SPP1--6377
RTN4R--6379
ISLR2--6414
ADRA2C--6524
GRHL3--6732
NBL1--6749
PTPRF--6764
TGIF1--16785
VAX1--6999
CXCL12--7204
NEUROG3--7305
LIN28A--7324
GDF7--7494
NOG--17650
THBS2--7963
CAPRIN2--8066
NUMBL--8142
ADRA2B--8196
IRX3--8539
TULP3--8569
ASCL2--8695
EGF0.2518839
ANAPC2--8902
HES3--8916
INPP5E--8975
GLI3--19032
SEMA7A--9127
ACE--9212
ATOH1--9258
GHRL0.2519333
SSH1--9532
FGF2--9627
NUMB--9921
RHOC--9929
OXT0.25110022
HOOK3--10195
LTK--10236
F2--110327
VWC2--10359
AVIL--10360
FIG4--110422
HEYL--10561
SCARF1--10690
INPPL1--11037
PMP22--111068
PTK20.25111177
RGS14--11308
STK11--111332
ABL2--11387
FEZF10.25111491
CTNNA1--11705
ARHGEF15--11779
PDLIM5--11934
TG--12189
DVL2--12293
EPO--12314
TRIM320.25112319
RYK--12768
REST--13067
LRRK2--113335
KATNA1--14304
CAPRIN1--14379
DGUOK--14448
PLK5--14706
TGFB10.25114736
SIX1--115117
LIG4--115324
PTK6--15561
ATF1--15773
KIF13B--15806
SEMA4D--15821
SHH--115942
TP73--15964
TNFRSF12A--16045
METRN--16077
DNMT3B--16091
DVL1P1--19166
TRPV4--119357
PSEN1--20241
CHRNB20.25120277
PLXNB2--20368
TTL--20378
EIF2AK3--20407
PTK7--20787
LIF--20888
AMIGO1--20910
DVL1--21155
APOE0.25121310
CCL5--21529
NEDD40.25121604
XRCC2--21673
NBN--121778
PRPF19--21797
EFNA1--21813
TWF2--21814
PPARG--121945
KLK8--22103
TRIM11--22145
CLCF1--22182
CALR--22356
NOTCH3--22751
XRCC6--23088
TIMP2--23119
FKBP4--23284
RNF10--23821
CTDSP1--23825
TRPV2--23894
ATF5--23952
P2RY2--24073
SERPINF1--24149
ARHGEF1--24198
CDK5RAP2--124345
CDK5RAP1--24534
CDC20--24914
XRCC4--24940
SSH3--25349
FXN--125366
ASPM--125468
CDK5RAP3--25488

Network

GO:0051960

Network
Enrichment
NameDescriptionExternal IDs
NTRK3neurotrophic tyrosine kinase, receptor, type 3 Entrez:4916  Ensembl: ENSG00000140538  HPRD: 01870  HGNC: 8033 
SNAP25synaptosomal-associated protein, 25kDa Entrez:6616  Ensembl: ENSG00000132639  HPRD: 02637  HGNC: 11132 
CNR1cannabinoid receptor 1 (brain) Entrez:1268  HGNC: 2159  Ensembl: ENSG00000118432  HPRD: 00259 
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  Ensembl: ENSG00000148053  HPRD: 02712  HGNC: 8032 
MAPTmicrotubule-associated protein tau Entrez:4137  HGNC: 6893  Ensembl: ENSG00000186868  HPRD: 01142 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK3neurotrophic tyrosine kinase, receptor, type 3
SNAP25synaptosomal-associated protein, 25kDa
CNR1cannabinoid receptor 1 (brain)
NTRK2neurotrophic tyrosine kinase, receptor, type 2
MAPTmicrotubule-associated protein tau
Query geneGeneGene descriptionEdge score
NTRK3NTRK3neurotrophic tyrosine kinase, receptor, type 3
SNAP25SNAP25synaptosomal-associated protein, 25kDa
CNR1CNR1cannabinoid receptor 1 (brain)
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
MAPTMAPTmicrotubule-associated protein tau

Troyanskaya Laboratory - Princeton University