ASD

GO:0031076 embryonic camera-type eye development (29)

GeneInput weightStandardRank
SOX11--66
PAX2--459
SP3--536
LRP6--778
PROX1--962
BMP7--987
HIPK1--1034
HIPK2--2306
TFAP2A--12460
WNT5A--2870
ALDH1A2--3466
WNT16--3772
FGF10--14373
IHH--14742
SMO0.2515864
TWIST1--16128
TH0.2516482
CRYAA--6901
STRA6--17612
TULP3--8569
KDM2B--8663
RDH10--9600
NES--11295
SP1--12422
FRS2--12610
ALDH1A3--15783
LRP5--116985
FZD5--21891
PPP1R13L--24182

Network

GO:0031076

Network
Enrichment
NameDescriptionExternal IDs
SOX11SRY (sex determining region Y)-box 11 Entrez:6664  HGNC: 11191  Ensembl: ENSG00000176887  HPRD: 02940 
PAX2paired box 2 Entrez:5076  HGNC: 8616  Ensembl: ENSG00000075891  HPRD: 01330 
SP3Sp3 transcription factor Entrez:6670  HPRD: 03483  HGNC: 11208  Ensembl: ENSG00000172845 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
PROX1prospero homeobox 1 Entrez:5629  HPRD: 03330  HGNC: 9459  Ensembl: ENSG00000117707 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX11SRY (sex determining region Y)-box 11
PAX2paired box 2
SP3Sp3 transcription factor
LRP6low density lipoprotein receptor-related protein 6
PROX1prospero homeobox 1
Query geneGeneGene descriptionEdge score
SOX11SOX11SRY (sex determining region Y)-box 11
PAX2PAX2paired box 2
SP3SP3Sp3 transcription factor
LRP6LRP6low density lipoprotein receptor-related protein 6
PROX1PROX1prospero homeobox 1

Troyanskaya Laboratory - Princeton University