ASD

GO:0033555 multicellular organismal response to stress (41)

GeneInput weightStandardRank
NEUROD2--68
GRIK20.51142
GRM70.251147
GABRA50.251157
CACNA1A--1231
MAPK8IP2--275
CRHR1--280
CACNA1B--319
RELN0.51436
CALCA--460
TAC10.251543
GRIN2B1.01599
DRD10.251662
NR2E10.251699
BDNF0.251754
PENK--835
ADRB1--866
NOS10.251908
PRL0.251992
RUNX1--11041
ADCYAP1R1--1132
TSPO0.2511277
ADRA2A0.2511556
CCK0.2511662
TRPA1--1981
GNG7--3138
LGALS1--3679
DBH0.2514946
KCNIP3--5329
GCH10.2516598
DRD40.2517058
TACR1--7688
TRPV10.2518765
COMT0.2519945
HMGCS2--10713
P2RX3--11797
GJA4--12229
VDAC1--14956
OSM--19901
IDO1--20843
MDK--22267

Network

GO:0033555

Network
Enrichment
NameDescriptionExternal IDs
NEUROD2neuronal differentiation 2 Entrez:4761  HPRD: 03429  HGNC: 7763 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  Ensembl: ENSG00000164418  HGNC: 4580  HPRD: 00692 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HGNC: 4599  Ensembl: ENSG00000196277  HPRD: 04979 
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5 Entrez:2558  Ensembl: ENSG00000186297  HPRD: 08840  HGNC: 4079 
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NEUROD2neuronal differentiation 2
GRIK2glutamate receptor, ionotropic, kainate 2
GRM7glutamate receptor, metabotropic 7
GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Query geneGeneGene descriptionEdge score
NEUROD2NEUROD2neuronal differentiation 2
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
GRM7GRM7glutamate receptor, metabotropic 7
GABRA5GABRA5gamma-aminobutyric acid (GABA) A receptor, alpha 5
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit

Troyanskaya Laboratory - Princeton University