ASD

GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process (30)

GeneInput weightStandardRank
SUMO1--178
AKT10.251303
TRIB2--534
CSNK1D--811
UBE2V2--1207
CSNK1E0.2511225
SMAD7--1283
RCHY1--1845
PSMD10--2012
PTEN1.012260
SUMO2--2503
STUB1--3156
TRIB1--3331
RNF180--3828
VCP--4121
PRICKLE1--15311
MDM2--5588
HSPBP1--6359
DNAJB2--7177
USP5--7638
LRRK2--113335
GCLC--13506
PSEN1--20241
TAF1--20307
GNB2L1--22873
NUB1--23472
FBXO22--24394
DAB2--24837
CLU--24939
PLK1--25689

Network

GO:0032436

Network
Enrichment
NameDescriptionExternal IDs
SUMO1small ubiquitin-like modifier 1 Entrez:7341  Ensembl: ENSG00000116030  HGNC: 12502  HPRD: 03554 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
CSNK1Dcasein kinase 1, delta Entrez:1453  Ensembl: ENSG00000141551  HGNC: 2452  HPRD: 02920 
UBE2V2ubiquitin-conjugating enzyme E2 variant 2 Entrez:7336  HPRD: 04300  HGNC: 12495 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SUMO1small ubiquitin-like modifier 1
AKT1v-akt murine thymoma viral oncogene homolog 1
TRIB2tribbles homolog 2 (Drosophila)
CSNK1Dcasein kinase 1, delta
UBE2V2ubiquitin-conjugating enzyme E2 variant 2
Query geneGeneGene descriptionEdge score
SUMO1SUMO1small ubiquitin-like modifier 1
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
TRIB2TRIB2tribbles homolog 2 (Drosophila)
CSNK1DCSNK1Dcasein kinase 1, delta
UBE2V2UBE2V2ubiquitin-conjugating enzyme E2 variant 2

Troyanskaya Laboratory - Princeton University