ASD

GO:0009125 nucleoside monophosphate catabolic process (16)

GeneInput weightStandardRank
PDE4D--357
HPRT1--1481
PDE4A--1000
PDE2A--1591
PDE4B--1754
PDE1B--1791
PDE11A--2107
PDE3A--3024
PDE3B--3088
PDE4C--4298
PDE5A--8315
NT5M--13851
AMPD3--15476
NT5E--16541
CNP--17352
DNPH1--24858

Network

GO:0009125

Network
Enrichment
NameDescriptionExternal IDs
PDE4Dphosphodiesterase 4D, cAMP-specific Entrez:5144  HPRD: 02530  HGNC: 8783  Ensembl: ENSG00000113448 
HPRT1hypoxanthine phosphoribosyltransferase 1 Entrez:3251  HGNC: 5157  HPRD: 02388  Ensembl: ENSG00000165704 
PDE4Aphosphodiesterase 4A, cAMP-specific Entrez:5141  HPRD: 02527  HGNC: 8780  Ensembl: ENSG00000065989 
PDE2Aphosphodiesterase 2A, cGMP-stimulated Entrez:5138  HGNC: 8777  Ensembl: ENSG00000186642  HPRD: 04041 
PDE4Bphosphodiesterase 4B, cAMP-specific Entrez:5142  HPRD: 02528  Ensembl: ENSG00000184588  HGNC: 8781 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PDE4Dphosphodiesterase 4D, cAMP-specific
HPRT1hypoxanthine phosphoribosyltransferase 1
PDE4Aphosphodiesterase 4A, cAMP-specific
PDE2Aphosphodiesterase 2A, cGMP-stimulated
PDE4Bphosphodiesterase 4B, cAMP-specific
Query geneGeneGene descriptionEdge score
PDE4DPDE4Dphosphodiesterase 4D, cAMP-specific
HPRT1HPRT1hypoxanthine phosphoribosyltransferase 1
PDE4APDE4Aphosphodiesterase 4A, cAMP-specific
PDE2APDE2Aphosphodiesterase 2A, cGMP-stimulated
PDE4BPDE4Bphosphodiesterase 4B, cAMP-specific

Troyanskaya Laboratory - Princeton University