ASD

GO:0035116 embryonic hindlimb morphogenesis (25)

GeneInput weightStandardRank
RARB0.251325
SMARCA4--751
LRP6--778
DICER1--1834
CHD7--1857
GNAS--12352
ALX3--2844
NOTCH1--13360
RSPO2--3476
MECOM--4397
WNT3--4799
FGF4--4827
MMP13--14872
GPC3--15153
BMP4--15180
ALX4--5466
OSR1--6192
CTNNB10.2516229
WNT7A--6375
MED1--6574
RARG0.25110956
SHH--115942
OSR2--18904
RPGRIP1L--19545
PITX10.25123078

Network

GO:0035116

Network
Enrichment
NameDescriptionExternal IDs
RARBretinoic acid receptor, beta Entrez:5915  HPRD: 07183  Ensembl: ENSG00000077092  HGNC: 9865 
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Entrez:6597  HPRD: 04459  HGNC: 11100  Ensembl: ENSG00000127616 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  Ensembl: ENSG00000070018  HGNC: 6698  HPRD: 04617 
DICER1dicer 1, ribonuclease type III Entrez:23405  HGNC: 17098  Ensembl: ENSG00000100697  HPRD: 05875 
CHD7chromodomain helicase DNA binding protein 7 Entrez:55636  Ensembl: ENSG00000171316  HGNC: 20626  HPRD: 10595 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
RARBretinoic acid receptor, beta
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
LRP6low density lipoprotein receptor-related protein 6
DICER1dicer 1, ribonuclease type III
CHD7chromodomain helicase DNA binding protein 7
Query geneGeneGene descriptionEdge score
RARBRARBretinoic acid receptor, beta
SMARCA4SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
LRP6LRP6low density lipoprotein receptor-related protein 6
DICER1DICER1dicer 1, ribonuclease type III
CHD7CHD7chromodomain helicase DNA binding protein 7

Troyanskaya Laboratory - Princeton University