ASD

GO:0042177 negative regulation of protein catabolic process (30)

GeneInput weightStandardRank
GRIN2A0.25156
FLNA--1984
PRKCG--11280
FYN--1284
RELA--1352
BAG6--1435
SMAD3--1541
AGAP2--1884
TIMP1--2285
HSP90AB1--2440
SERPINE2--2896
SMAD4--2927
USP44--3386
N4BP1--3558
FURIN--4868
PTPN3--5124
TAF9--5472
SERPINB12--5630
GRIN2C--6011
NOS20.2517024
IL10--17883
MAD2L2--11317
IRAK3--14013
GIPC1--15140
SHH--115942
INS--119021
TIMP3--20931
MDM4--21248
UBXN1--22532
MAD2L1--22813

Network

GO:0042177

Network
Enrichment
NameDescriptionExternal IDs
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HGNC: 4585  Ensembl: ENSG00000183454  HPRD: 00698 
FLNAfilamin A, alpha Entrez:2316  HPRD: 02060  HGNC: 3754  Ensembl: ENSG00000196924 
PRKCGprotein kinase C, gamma Entrez:5582  HGNC: 9402  HPRD: 01502  Ensembl: ENSG00000126583 
FYNFYN oncogene related to SRC, FGR, YES Entrez:2534  HGNC: 4037  Ensembl: ENSG00000010810  HPRD: 00655 
RELAv-rel avian reticuloendotheliosis viral oncogene homolog A Entrez:5970  HGNC: 9955  HPRD: 01241  Ensembl: ENSG00000173039 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
FLNAfilamin A, alpha
PRKCGprotein kinase C, gamma
FYNFYN oncogene related to SRC, FGR, YES
RELAv-rel avian reticuloendotheliosis viral oncogene homolog A
Query geneGeneGene descriptionEdge score
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
FLNAFLNAfilamin A, alpha
PRKCGPRKCGprotein kinase C, gamma
FYNFYNFYN oncogene related to SRC, FGR, YES
RELARELAv-rel avian reticuloendotheliosis viral oncogene homolog A

Troyanskaya Laboratory - Princeton University