ASD

GO:0010469 regulation of receptor activity (42)

GeneInput weightStandardRank
PPP2CA--21
CACNG3--83
NLGN10.251265
MAPK8IP2--275
ADORA1--498
FBXW7--525
CACNG2--1099
CACNG4--1407
ADRA2A0.2511556
TGFA--1563
CNIH3--1978
APP--1991
PPP2R5B--2024
UBE2I--2101
CACNG5--4340
P2RY1--4483
NCK2--4595
CNIH2--4683
PRKCD--5824
SHC1--5839
ADRA2C--6524
PLAU--7091
PTPRJ--17218
ERRFI1--7414
ADRA2B--8196
ZFYVE28--8207
PCSK9--8260
CACNG8--8390
EREG--8504
EGF0.2518839
CACNG7--9280
ADAM17--11074
EPGN--11496
PPARGC1B--116411
PSEN1--20241
HDAC6--20439
SERPINE10.25120720
CBLC--20918
PSEN2--21431
ZGPAT--22147
SNX6--22785
IGF20.25123391

Network

GO:0010469

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
CACNG3calcium channel, voltage-dependent, gamma subunit 3 Entrez:10368  HGNC: 1407  Ensembl: ENSG00000006116  HPRD: 05910 
NLGN1neuroligin 1 Entrez:22871  HGNC: 14291  HPRD: 07195  Ensembl: ENSG00000169760 
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2 Entrez:23542  HPRD: 09674  Ensembl: ENSG00000008735  HGNC: 6883 
ADORA1adenosine A1 receptor Entrez:134  HPRD: 00042  Ensembl: ENSG00000163485  HGNC: 262 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
CACNG3calcium channel, voltage-dependent, gamma subunit 3
NLGN1neuroligin 1
MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
ADORA1adenosine A1 receptor
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
CACNG3CACNG3calcium channel, voltage-dependent, gamma subunit 3
NLGN1NLGN1neuroligin 1
MAPK8IP2MAPK8IP2mitogen-activated protein kinase 8 interacting protein 2
ADORA1ADORA1adenosine A1 receptor

Troyanskaya Laboratory - Princeton University