ASD

GO:0045749 negative regulation of S phase of mitotic cell cycle (10)

GeneInput weightStandardRank
MYO160.251386
SMARCA4--751
APBB2--1049
APBB1--2444
CHMP1A--2805
RB1--13450
BCL6--3994
GAS1--5960
DCUN1D3--9959
CRLF3--22462

Network

GO:0045749

Network
Enrichment
NameDescriptionExternal IDs
MYO16myosin XVI Entrez:23026  Ensembl: ENSG00000041515  HGNC: 29822  HPRD: 14795 
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4 Entrez:6597  HPRD: 04459  HGNC: 11100  Ensembl: ENSG00000127616 
APBB2amyloid beta (A4) precursor protein-binding, family B, member 2 Entrez:323  HGNC: 582  HPRD: 04088  Ensembl: ENSG00000163697 
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65) Entrez:322  HGNC: 581  Ensembl: ENSG00000166313  HPRD: 04087 
CHMP1Acharged multivesicular body protein 1A Entrez:5119  Ensembl: ENSG00000131165  HGNC: 8740  HPRD: 01237 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MYO16myosin XVI
SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
APBB2amyloid beta (A4) precursor protein-binding, family B, member 2
APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
CHMP1Acharged multivesicular body protein 1A
Query geneGeneGene descriptionEdge score
MYO16MYO16myosin XVI
SMARCA4SMARCA4SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
APBB2APBB2amyloid beta (A4) precursor protein-binding, family B, member 2
APBB1APBB1amyloid beta (A4) precursor protein-binding, family B, member 1 (Fe65)
CHMP1ACHMP1Acharged multivesicular body protein 1A

Troyanskaya Laboratory - Princeton University