ASD

GO:0043405 regulation of MAP kinase activity (205)

GeneInput weightStandardRank
PPP2CA--21
HTR2A0.25151
RGS4--99
KRAS--1143
UCHL1--1317
MAPK8IP1--1326
NF10.251333
MAP2K10.251474
MAP3K9--500
GRM10.251523
TRIB2--534
GNG3--591
SPRED2--643
DUSP8--796
PPP2R1A--852
PDCD10--883
MADD--898
MAPK1--985
BMP7--987
MAP2K20.2511066
MAP3K5--1245
MAPK11--1258
SPRED1--1282
DUSP5--1317
SPAG9--1398
EDN3--11522
SPRY2--1552
ADRA2A0.2511556
TGFA--1563
CHRNA70.511657
MAP3K10--1767
CD81--11828
GAB1--1864
DUSP6--1889
PKN1--1964
GPS1--2030
HMGCR--2128
DUSP1--2140
MAP3K7--2169
MAPK8IP3--2496
FZD10--2606
TAB2--2777
EGFR--12811
WNT5A--2870
ILK--2917
NOX4--2930
LPAR1--2975
PTK2B--3191
PDE6H--3301
SOD1--13330
TRIB1--3331
MAPKAPK2--3441
SPRY4--3540
MET1.013618
DAB2IP--3635
PROK2--13667
RGS2--3677
CXCR4--4014
CBS0.2514080
HGF0.2514189
DUSP4--4300
FGF10--14373
DVL3--4438
PLA2G1B--4440
GH1--4570
ZEB2--4607
TNFRSF11A--14672
PDGFA--4678
VEGFA0.2514691
MAPK14--4729
ADIPOQ0.2514834
MAP4K5--4887
PDCD4--4897
DUSP19--5073
BMP4--15180
HTR2B--5233
TGFB3--15321
PAK1--5556
UBC--5781
GRM4--5804
PRKCD--5824
SHC1--5839
DUSP3--5845
MAPK30.2516096
DUSP10--6196
IL1B--16220
WNT7A--6375
PPEF2--6387
TAB3--6412
ADRA2C--6524
MAP3K4--6590
MAP3K1--16751
TDGF1--6833
DRD40.2517058
PTPRJ--17218
TLR4--17283
C1QTNF2--7354
DUSP7--7411
DUSP9--7653
PLCE1--7692
WNT7B--7693
DUSP2--7903
TLR6--7973
ADRA2B--8196
PROK1--8256
MAP2K7--8382
EGF0.2518839
PRDX2--8945
MAP2K3--9005
IRAK1--9309
GHRL0.2519333
NUP62--19343
EDN1--9566
FGF2--9627
DAXX--9639
TAB1--9783
DUSP16--9952
MAP3K2--10013
GHR--110058
PIK3CB--10067
MAP2K6--10398
GSTP10.25110429
LPAR3--10488
SPRY1--10579
CAV3--110580
MBIP--10795
LAX1--10896
AXIN1--110905
INSR--110986
INPPL1--11037
ADORA2B--11164
RGS14--11308
TSC20.25111448
IRAK2--11461
EPGN--11496
HIPK3--11588
FGD4--111677
ELANE--111717
MDFI--11799
CCL19--11890
BIRC7--12220
DVL2--12293
TLR9--12436
PDGFB--12484
FRS2--12610
CD24--113608
RIPK2--13928
ITGA1--13957
IRAK3--14013
IQGAP3--14020
FPR1--14197
DBNL--14433
LPAR2--14606
MDFIC--14627
TGFB10.25114736
TRAF6--14847
ZNF675--15034
STK380.25115423
C5--115436
TP73--15964
C5AR1--16349
TRIB3--16821
S1PR2--18246
SPRED3--19822
TNF0.25119823
PDE6G--119831
AJUBA--19840
TPD52L1--20081
PSEN1--20241
GPS2--20293
ADAM8--20729
CBLC--20918
MAP4K2--20924
PDGFRB--21054
APOE0.25121310
ERBB2--121638
EFNA1--21813
RGS3--21940
THBS1--21993
UBB--22223
MAP4K1--22293
MUL1--22450
CD74--22633
NOD2--122677
PTPLAD1--22865
RPS27A--22920
RIPK1--23173
MAP3K11--23341
AVPI1--23367
TRAF2--23633
MAPKAPK3--23643
NOD1--23711
SYK--23795
IKBKG--123817
CDK1--24001
SMPD1--124037
UBA52--24116
PRKAA1--24385
MAP3K6--24401
GBA--124709
CAV1--124767
IL1RN0.25124819
CDK12--24892
AIDA--25079
DUSP22--25132

Network

GO:0043405

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HGNC: 9299  HPRD: 08912 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HPRD: 01638  Ensembl: ENSG00000102468  HGNC: 5293 
RGS4regulator of G-protein signaling 4 Entrez:5999  HGNC: 10000  HPRD: 03947  Ensembl: ENSG00000117152 
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  Ensembl: ENSG00000133703  HGNC: 6407  HPRD: 01817 
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) Entrez:7345  HPRD: 01877  HGNC: 12513  Ensembl: ENSG00000154277 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
RGS4regulator of G-protein signaling 4
KRASKirsten rat sarcoma viral oncogene homolog
UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
RGS4RGS4regulator of G-protein signaling 4
KRASKRASKirsten rat sarcoma viral oncogene homolog
UCHL1UCHL1ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)

Troyanskaya Laboratory - Princeton University