ASD

GO:0032350 regulation of hormone metabolic process (21)

GeneInput weightStandardRank
CACNA1A--1231
NR3C1--463
IGF1R--631
HIF1A--1008
POR0.2512359
LHCGR0.2512362
PAX8--13021
STUB1--3156
CYP17A10.2513171
GATA3--3207
BMP6--3242
DKK3--4056
ATP1A10.2514084
TCF7L2--15670
TRERF1--8876
GAL--9612
REST--13067
KDM1A--15967
WNT4--21840
IGF20.25123391
ARNT--24282

Network

GO:0032350

Network
Enrichment
NameDescriptionExternal IDs
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit Entrez:773  HPRD: 03004  HGNC: 1388  Ensembl: ENSG00000141837 
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) Entrez:2908  HPRD: 00679  HGNC: 7978  Ensembl: ENSG00000113580 
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  Ensembl: ENSG00000140443  HPRD: 00932  HGNC: 5465 
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) Entrez:3091  HGNC: 4910  Ensembl: ENSG00000100644  HPRD: 04517 
PORP450 (cytochrome) oxidoreductase Entrez:5447  HGNC: 9208  Ensembl: ENSG00000127948  HPRD: 00485 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
CACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
IGF1Rinsulin-like growth factor 1 receptor
HIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
PORP450 (cytochrome) oxidoreductase
Query geneGeneGene descriptionEdge score
CACNA1ACACNA1Acalcium channel, voltage-dependent, P/Q type, alpha 1A subunit
NR3C1NR3C1nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor)
IGF1RIGF1Rinsulin-like growth factor 1 receptor
HIF1AHIF1Ahypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
PORPORP450 (cytochrome) oxidoreductase

Troyanskaya Laboratory - Princeton University