ASD

GO:0008593 regulation of Notch signaling pathway (20)

GeneInput weightStandardRank
MEG3--201
ASCL1--229
FBXW7--525
DLL3--1816
BMP7--987
HEY1--1114
JAG1--12588
GATA2--12710
WNT1--3263
HEY2--3529
FGF10--14373
DTX1--5135
NFKBIA--6067
POSTN--6100
MESP1--10948
OVOL2--13406
NRARP--15165
NOD2--122677
TP63--124113
C12orf52--24985

Network

GO:0008593

Network
Enrichment
NameDescriptionExternal IDs
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
ASCL1achaete-scute complex homolog 1 (Drosophila) Entrez:429  HPRD: 00011  Ensembl: ENSG00000139352  HGNC: 738 
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HPRD: 05888  Ensembl: ENSG00000109670  HGNC: 16712 
DLL3delta-like 3 (Drosophila) Entrez:10683  Ensembl: ENSG00000090932  HGNC: 2909  HPRD: 04140 
BMP7bone morphogenetic protein 7 Entrez:655  Ensembl: ENSG00000101144  HGNC: 1074  HPRD: 00212 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
MEG3maternally expressed 3 (non-protein coding)
ASCL1achaete-scute complex homolog 1 (Drosophila)
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
DLL3delta-like 3 (Drosophila)
BMP7bone morphogenetic protein 7
Query geneGeneGene descriptionEdge score
MEG3MEG3maternally expressed 3 (non-protein coding)
ASCL1ASCL1achaete-scute complex homolog 1 (Drosophila)
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
DLL3DLL3delta-like 3 (Drosophila)
BMP7BMP7bone morphogenetic protein 7

Troyanskaya Laboratory - Princeton University