ASD

GO:0061136 regulation of proteasomal protein catabolic process (52)

GeneInput weightStandardRank
SUMO1--178
PSMD14--120
AKT10.251303
TRIB2--534
CSNK1D--811
RAD23B--868
WNT10B--1030
UBE2V2--1207
CSNK1E0.2511225
SMAD7--1283
BAG6--1435
USP14--1445
RCHY1--1845
PSMD10--2012
PTEN1.012260
BTRC--2430
HSP90AB1--2440
SUMO2--2503
STUB1--3156
TRIB1--3331
USP44--3386
N4BP1--3558
RNF180--3828
VCP--4121
PRICKLE1--15311
TAF9--5472
MDM2--5588
HSPBP1--6359
GPX10.2516748
DNAJB2--7177
USP5--7638
MAD2L2--11317
RAD23A--12130
DYX1C10.25112369
LRRK2--113335
GCLC--13506
GIPC1--15140
SHH--115942
PSME3--17451
PSEN1--20241
TAF1--20307
COMMD1--22050
UBXN1--22532
MAD2L1--22813
GNB2L1--22873
NUB1--23472
UCHL5--23734
FBXO22--24394
RHBDF1--24539
DAB2--24837
CLU--24939
PLK1--25689

Network

GO:0061136

Network
Enrichment
NameDescriptionExternal IDs
SUMO1small ubiquitin-like modifier 1 Entrez:7341  Ensembl: ENSG00000116030  HGNC: 12502  HPRD: 03554 
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 Entrez:10213  HGNC: 16889  Ensembl: ENSG00000115233  HPRD: 06208 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HPRD: 01261  Ensembl: ENSG00000142208  HGNC: 391 
TRIB2tribbles homolog 2 (Drosophila) Entrez:28951  HPRD: 18224  HGNC: 30809  Ensembl: ENSG00000071575 
CSNK1Dcasein kinase 1, delta Entrez:1453  Ensembl: ENSG00000141551  HGNC: 2452  HPRD: 02920 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SUMO1small ubiquitin-like modifier 1
PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
AKT1v-akt murine thymoma viral oncogene homolog 1
TRIB2tribbles homolog 2 (Drosophila)
CSNK1Dcasein kinase 1, delta
Query geneGeneGene descriptionEdge score
SUMO1SUMO1small ubiquitin-like modifier 1
PSMD14PSMD14proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
TRIB2TRIB2tribbles homolog 2 (Drosophila)
CSNK1DCSNK1Dcasein kinase 1, delta

Troyanskaya Laboratory - Princeton University