ASD

Genome-wide predictions of autism-associated genes

Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by deficits in social communication and restricted, repetitive patterns of behavior. ASD has a strong genetic basis but we still lack the full complement of autism-associated genes.

Here we present a genome-wide prediction of autism-associated genes based on known disease genes in the context of a human brain-specific gene interaction network.

Citation

Krishnan A*, Zhang R*, Yao V, Theesfeld CL, Wong AK, Tadych A, Volfovsky N, Packer A, Lash A, Troyanskaya OG.(2016) Genome-wide prediction and functional characterization of the genetic basis of autism spectrum disorder. Nature Neuroscience.

Use the table below to explore brain-specific interactions between top-ranked ASD-genes, as well as ASD-associated cellular processes and pathways, aspects of the developing human brain, and recurrent copy-number variants (CNVs).

Rank ?Gene ?Standard ?Evidence ? Probability ? p-value ? q-value ? FMRP ?CHD8 ?TOP1 ?WNT ?MAPK ?PSD ?
ID ?Description ?Number of genes ?Score ?
GO:0048812 neuron projection morphogenesis 464 19.399099
GO:0048667 cell morphogenesis involved in neuron differentiation 452 19.285928
GO:0007409 axonogenesis 433 18.854904
GO:0007411 axon guidance 344 16.414029
GO:0007420 brain development 411 15.512536
GO:0007610 behavior 335 15.43623
GO:0031644 regulation of neurological system process 188 14.803976
GO:0051969 regulation of transmission of nerve impulse 176 14.573099
GO:0050804 regulation of synaptic transmission 162 14.553161
GO:0060284 regulation of cell development 386 14.292086
GO:0051960 regulation of nervous system development 338 14.14312
GO:0050767 regulation of neurogenesis 306 13.491331
GO:0030900 forebrain development 225 13.404601
GO:0044057 regulation of system process 381 13.37504
GO:0045664 regulation of neuron differentiation 258 12.941141
GO:0050890 cognition 136 12.607527
GO:0007611 learning or memory 125 12.182418
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway 488 11.885165
GO:0021537 telencephalon development 132 11.263247
GO:0007423 sensory organ development 337 10.766363
GO:0045597 positive regulation of cell differentiation 379 10.707297
GO:0042391 regulation of membrane potential 163 10.589111
GO:0007156 homophilic cell adhesion 139 10.559077
GO:0006836 neurotransmitter transport 107 10.544773
GO:0045944 positive regulation of transcription from RNA polymerase II promoter 494 10.537866
GO:0048167 regulation of synaptic plasticity 78 10.481789
GO:0030001 metal ion transport 468 10.391314
GO:0023057 negative regulation of signaling 484 10.387761
GO:0045761 regulation of adenylate cyclase activity 105 10.372069
GO:0010975 regulation of neuron projection development 162 10.351646
GO:0010648 negative regulation of cell communication 484 10.350428
GO:0031279 regulation of cyclase activity 108 10.328266
GO:0048011 nerve growth factor receptor signaling pathway 218 10.28868
GO:0030817 regulation of cAMP biosynthetic process 122 10.285338
GO:0007626 locomotory behavior 108 10.223838
GO:0007612 learning 68 10.212385
GO:0030814 regulation of cAMP metabolic process 123 10.162139
GO:0010769 regulation of cell morphogenesis involved in differentiation 146 10.159235
GO:0030802 regulation of cyclic nucleotide biosynthetic process 132 10.108449
GO:0030808 regulation of nucleotide biosynthetic process 132 10.108449
GO:0051339 regulation of lyase activity 110 10.089811
GO:0030799 regulation of cyclic nucleotide metabolic process 137 10.001855
GO:0060341 regulation of cellular localization 466 9.958384
GO:0051046 regulation of secretion 357 9.779359
GO:0031344 regulation of cell projection organization 195 9.723321
GO:0046883 regulation of hormone secretion 152 9.698225
GO:0048168 regulation of neuronal synaptic plasticity 43 9.692055
GO:0019933 cAMP-mediated signaling 118 9.583419
GO:0003001 generation of a signal involved in cell-cell signaling 116 9.502012
GO:0023061 signal release 116 9.502012
GO:0021543 pallium development 80 9.486162
GO:0019932 second-messenger-mediated signaling 312 9.485315
GO:0051093 negative regulation of developmental process 394 9.404263
GO:0015672 monovalent inorganic cation transport 317 9.40411
GO:0001505 regulation of neurotransmitter levels 97 9.388272
GO:0045165 cell fate commitment 161 9.342859
GO:0019935 cyclic-nucleotide-mediated signaling 154 9.325086
GO:0006813 potassium ion transport 156 9.254423
GO:0002791 regulation of peptide secretion 126 9.217781
GO:0090087 regulation of peptide transport 126 9.217781
GO:0007187 G-protein signaling, coupled to cyclic nucleotide second messenger 140 9.172232
GO:0055082 cellular chemical homeostasis 468 9.172199
GO:0090276 regulation of peptide hormone secretion 124 9.169835
GO:0007269 neurotransmitter secretion 67 9.166084
GO:0030534 adult behavior 81 9.117256
GO:0022603 regulation of anatomical structure morphogenesis 419 9.102209
GO:0007188 G-protein signaling, coupled to cAMP nucleotide second messenger 107 9.01906
GO:0001654 eye development 216 8.97448
GO:0009968 negative regulation of signal transduction 447 8.911876
GO:0006140 regulation of nucleotide metabolic process 349 8.902584
GO:0045596 negative regulation of cell differentiation 320 8.889979
GO:0007389 pattern specification process 343 8.847583
GO:0071495 cellular response to endogenous stimulus 365 8.756362
GO:0010721 negative regulation of cell development 91 8.732516
GO:0021953 central nervous system neuron differentiation 90 8.72459
GO:0010720 positive regulation of cell development 133 8.715644
GO:0048638 regulation of developmental growth 83 8.681901
GO:0033238 regulation of cellular amine metabolic process 68 8.648834
GO:0022604 regulation of cell morphogenesis 211 8.617776
GO:0006873 cellular ion homeostasis 447 8.580873
GO:0043269 regulation of ion transport 167 8.574422
GO:0048169 regulation of long-term neuronal synaptic plasticity 24 8.573612
GO:0000122 negative regulation of transcription from RNA polymerase II promoter 335 8.570226
GO:0006521 regulation of cellular amino acid metabolic process 55 8.560446
GO:0032870 cellular response to hormone stimulus 330 8.551747
GO:0050796 regulation of insulin secretion 117 8.549978
GO:0048598 embryonic morphogenesis 377 8.526061
GO:0048732 gland development 211 8.488758
GO:0003002 regionalization 234 8.425203
GO:0048568 embryonic organ development 249 8.420222
GO:0050770 regulation of axonogenesis 85 8.251925
GO:0007202 activation of phospholipase C activity 105 8.242867
GO:0016337 cell-cell adhesion 296 8.229711
GO:0010959 regulation of metal ion transport 143 8.222849
GO:0021761 limbic system development 57 8.201136
GO:0050801 ion homeostasis 489 8.186566
GO:0010863 positive regulation of phospholipase C activity 106 8.172068
GO:0007194 negative regulation of adenylate cyclase activity 55 8.157812
GO:0031280 negative regulation of cyclase activity 55 8.157812
GO:0051350 negative regulation of lyase activity 55 8.157812
GO:0008344 adult locomotory behavior 51 8.127928
GO:0050769 positive regulation of neurogenesis 102 8.113241
GO:0043010 camera-type eye development 183 8.1107
GO:0042063 gliogenesis 109 8.095313
GO:0051588 regulation of neurotransmitter transport 36 8.094194
GO:0001764 neuron migration 74 8.034386
GO:0048511 rhythmic process 179 7.964415
GO:0033555 multicellular organismal response to stress 41 7.963976
GO:0001501 skeletal system development 317 7.944373
GO:0035295 tube development 319 7.913321
GO:0048592 eye morphogenesis 102 7.912111
GO:0050768 negative regulation of neurogenesis 75 7.903963
GO:0048562 embryonic organ morphogenesis 172 7.842653
GO:0001508 regulation of action potential 89 7.832708
GO:0007600 sensory perception 441 7.764921
GO:0010518 positive regulation of phospholipase activity 111 7.749266
GO:0044087 regulation of cellular component biogenesis 241 7.747951
GO:0008038 neuron recognition 26 7.721818
GO:0010517 regulation of phospholipase activity 117 7.704354
GO:0010001 glial cell differentiation 95 7.678601
GO:0007416 synapse assembly 34 7.641657
GO:0006112 energy reserve metabolic process 141 7.55167
GO:0072395 signal transduction involved in cell cycle checkpoint 64 7.535584
GO:0072404 signal transduction involved in G1/S transition checkpoint 64 7.535584
GO:0048593 camera-type eye morphogenesis 73 7.518801
GO:0007215 glutamate signaling pathway 26 7.467205
GO:0043434 response to peptide hormone stimulus 354 7.461704
GO:0060041 retina development in camera-type eye 76 7.438295
GO:0021954 central nervous system neuron development 36 7.42851
GO:0021987 cerebral cortex development 54 7.417713
GO:0048489 synaptic vesicle transport 42 7.400445
GO:0021766 hippocampus development 42 7.387086
GO:0050805 negative regulation of synaptic transmission 33 7.366059
GO:0043583 ear development 135 7.333147
GO:0009792 embryo development ending in birth or egg hatching 397 7.330589
GO:0048839 inner ear development 112 7.327055
GO:0032228 regulation of synaptic transmission, GABAergic 24 7.305634
GO:0043009 chordate embryonic development 390 7.291622
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest 63 7.278639
GO:0072401 signal transduction involved in DNA integrity checkpoint 63 7.278639
GO:0072413 signal transduction involved in mitotic cell cycle checkpoint 63 7.278639
GO:0072422 signal transduction involved in DNA damage checkpoint 63 7.278639
GO:0072431 signal transduction involved in mitotic cell cycle G1/S transition DNA damage checkpoint 63 7.278639
GO:0072474 signal transduction involved in mitotic cell cycle G1/S checkpoint 63 7.278639
GO:0051970 negative regulation of transmission of nerve impulse 37 7.275806
GO:0008306 associative learning 41 7.232005
GO:0046928 regulation of neurotransmitter secretion 28 7.230726
GO:0009952 anterior/posterior pattern formation 159 7.221462
GO:0045762 positive regulation of adenylate cyclase activity 62 7.218008
GO:0014047 glutamate secretion 17 7.213994
GO:0051130 positive regulation of cellular component organization 363 7.168229
GO:0051924 regulation of calcium ion transport 121 7.153831
GO:0051899 membrane depolarization 44 7.134271
GO:0060193 positive regulation of lipase activity 119 7.116979
GO:0090066 regulation of anatomical structure size 411 7.115311
GO:0034220 ion transmembrane transport 202 7.114033
GO:0031281 positive regulation of cyclase activity 63 7.085595
GO:0071375 cellular response to peptide hormone stimulus 237 7.079748
GO:0060191 regulation of lipase activity 140 7.066245
GO:0031645 negative regulation of neurological system process 41 7.058171
GO:0040008 regulation of growth 441 7.046838
GO:0007613 memory 53 7.014543
GO:0007190 activation of adenylate cyclase activity 61 6.975933
GO:0030902 hindbrain development 89 6.966054
GO:0007193 inhibition of adenylate cyclase activity by G-protein signaling pathway 43 6.952207
GO:0035239 tube morphogenesis 209 6.941386
GO:0009894 regulation of catabolic process 394 6.92584
GO:0051050 positive regulation of transport 352 6.90488
GO:0021510 spinal cord development 62 6.901774
GO:0007507 heart development 295 6.865958
GO:0051129 negative regulation of cellular component organization 249 6.864102
GO:0071158 positive regulation of cell cycle arrest 70 6.862182
GO:0007214 gamma-aminobutyric acid signaling pathway 19 6.849356
GO:0031646 positive regulation of neurological system process 41 6.844537
GO:0032535 regulation of cellular component size 367 6.841932
GO:0051349 positive regulation of lyase activity 65 6.788237
GO:0048729 tissue morphogenesis 337 6.786182
GO:0032412 regulation of ion transmembrane transporter activity 65 6.778073
GO:0045665 negative regulation of neuron differentiation 49 6.740016
GO:0050773 regulation of dendrite development 40 6.732553
GO:0031345 negative regulation of cell projection organization 52 6.720552
GO:0032940 secretion by cell 328 6.716633
GO:0022898 regulation of transmembrane transporter activity 69 6.701589
GO:0050808 synapse organization 61 6.700422
GO:0051971 positive regulation of transmission of nerve impulse 38 6.697989
GO:0031571 mitotic cell cycle G1/S transition DNA damage checkpoint 70 6.684249
GO:0046903 secretion 447 6.671152
GO:0045666 positive regulation of neuron differentiation 52 6.670305
GO:0003006 developmental process involved in reproduction 363 6.667827
GO:0007270 neuron-neuron synaptic transmission 35 6.649259
GO:0043523 regulation of neuron apoptosis 133 6.63329
GO:0030705 cytoskeleton-dependent intracellular transport 35 6.631169
GO:0022029 telencephalon cell migration 33 6.592558
GO:0031401 positive regulation of protein modification process 335 6.573584
GO:0050806 positive regulation of synaptic transmission 35 6.564251
GO:0030168 platelet activation 241 6.55934
GO:0050905 neuromuscular process 65 6.545157
GO:0032409 regulation of transporter activity 78 6.544029
GO:0000165 MAPKKK cascade 226 6.540875
GO:0051966 regulation of synaptic transmission, glutamatergic 24 6.538369
GO:0016079 synaptic vesicle exocytosis 23 6.531385
GO:0021885 forebrain cell migration 35 6.531052
GO:0043086 negative regulation of catalytic activity 438 6.521924
GO:0006816 calcium ion transport 121 6.513972
GO:0060078 regulation of postsynaptic membrane potential 29 6.501263
GO:0040012 regulation of locomotion 318 6.491677
GO:0008542 visual learning 26 6.450838
GO:0001763 morphogenesis of a branching structure 142 6.449862
GO:0007632 visual behavior 30 6.44764
GO:0048706 embryonic skeletal system development 88 6.391107
GO:0048736 appendage development 118 6.368652
GO:0060173 limb development 118 6.368652
GO:0034765 regulation of ion transmembrane transport 76 6.367087
GO:0009205 purine ribonucleoside triphosphate metabolic process 301 6.357594
GO:0031290 retinal ganglion cell axon guidance 14 6.342483
GO:0042596 fear response 17 6.341134
GO:0051247 positive regulation of protein metabolic process 429 6.33577
GO:2000027 regulation of organ morphogenesis 94 6.331487
GO:0007422 peripheral nervous system development 62 6.325814
GO:0014013 regulation of gliogenesis 48 6.318525
GO:0009199 ribonucleoside triphosphate metabolic process 302 6.293936
GO:0019228 regulation of action potential in neuron 71 6.281404
GO:0021700 developmental maturation 123 6.263911
GO:0035107 appendage morphogenesis 111 6.258359
GO:0035108 limb morphogenesis 111 6.258359
GO:0001964 startle response 18 6.248382
GO:0002009 morphogenesis of an epithelium 248 6.230735
GO:0009144 purine nucleoside triphosphate metabolic process 305 6.225282
GO:0006184 GTP catabolic process 152 6.223729
GO:0002474 antigen processing and presentation of peptide antigen via MHC class I 83 6.206453
GO:0032270 positive regulation of cellular protein metabolic process 413 6.196572
GO:0003007 heart morphogenesis 130 6.190478
GO:0030516 regulation of axon extension 39 6.164854
GO:0016477 cell migration 456 6.161221
GO:0051345 positive regulation of hydrolase activity 386 6.14717
GO:0043524 negative regulation of neuron apoptosis 74 6.115388
GO:0009141 nucleoside triphosphate metabolic process 312 6.102348
GO:0048705 skeletal system morphogenesis 139 6.08799
GO:0070647 protein modification by small protein conjugation or removal 405 6.06793
GO:0090068 positive regulation of cell cycle process 122 6.067734
GO:0060485 mesenchyme development 98 6.052631
GO:0008361 regulation of cell size 286 6.036593
GO:0048663 neuron fate commitment 45 6.014421
GO:0071779 G1/S transition checkpoint 80 6.011886
GO:0007218 neuropeptide signaling pathway 93 6.006654
GO:0032868 response to insulin stimulus 233 5.998388
GO:0031400 negative regulation of protein modification process 168 5.972918
GO:0050678 regulation of epithelial cell proliferation 156 5.963603
GO:0051270 regulation of cellular component movement 311 5.958929
GO:0030330 DNA damage response, signal transduction by p53 class mediator 88 5.956009
GO:0060562 epithelial tube morphogenesis 164 5.931841
GO:0031346 positive regulation of cell projection organization 105 5.908425
GO:0007631 feeding behavior 76 5.904327
GO:0051443 positive regulation of ubiquitin-protein ligase activity 79 5.899971
GO:0050803 regulation of synapse structure and activity 38 5.894681
GO:0006163 purine nucleotide metabolic process 391 5.888555
GO:0002209 behavioral defense response 14 5.88513
GO:0046039 GTP metabolic process 164 5.884098
GO:0051925 regulation of calcium ion transport via voltage-gated calcium channel activity 42 5.881435
GO:0021781 glial cell fate commitment 14 5.850479
GO:0010970 microtubule-based transport 31 5.848269
GO:0001655 urogenital system development 169 5.846022
GO:0042176 regulation of protein catabolic process 120 5.84581
GO:0048762 mesenchymal cell differentiation 84 5.836034
GO:0007264 small GTPase mediated signal transduction 393 5.831229
GO:0070838 divalent metal ion transport 150 5.795241
GO:0030334 regulation of cell migration 283 5.779862
GO:0007272 ensheathment of neurons 59 5.777677
GO:0008366 axon ensheathment 59 5.777677
GO:0042552 myelination 55 5.776308
GO:0031575 mitotic cell cycle G1/S transition checkpoint 79 5.767164
GO:0030278 regulation of ossification 114 5.750316
GO:0007548 sex differentiation 226 5.738345
GO:0060079 regulation of excitatory postsynaptic membrane potential 23 5.736505
GO:0016358 dendrite development 41 5.736187
GO:0048002 antigen processing and presentation of peptide antigen 90 5.734158
GO:0008016 regulation of heart contraction 89 5.729551
GO:0043279 response to alkaloid 86 5.719851
GO:0017157 regulation of exocytosis 59 5.719199
GO:0007200 activation of phospholipase C activity by G-protein coupled receptor protein signaling pathway coupled to IP3 second messenger 54 5.714508
GO:0048639 positive regulation of developmental growth 36 5.698602
GO:0050771 negative regulation of axonogenesis 31 5.697739
GO:0048608 reproductive structure development 212 5.696799
GO:0007616 long-term memory 15 5.689446
GO:0030324 lung development 124 5.671885
GO:0072331 signal transduction by p53 class mediator 92 5.671619
GO:0048634 regulation of muscle organ development 70 5.651567
GO:0007178 transmembrane receptor protein serine/threonine kinase signaling pathway 107 5.646467
GO:0021536 diencephalon development 55 5.644148
GO:0007173 epidermal growth factor receptor signaling pathway 77 5.628128
GO:0001709 cell fate determination 40 5.617996
GO:0007189 activation of adenylate cyclase activity by G-protein signaling pathway 47 5.617876
GO:0010578 regulation of adenylate cyclase activity involved in G-protein signaling pathway 47 5.617876
GO:0010579 positive regulation of adenylate cyclase activity by G-protein signaling pathway 47 5.617876
GO:0060541 respiratory system development 142 5.614809
GO:0051147 regulation of muscle cell differentiation 74 5.604413
GO:0031333 negative regulation of protein complex assembly 55 5.592978
GO:0045685 regulation of glial cell differentiation 39 5.590103
GO:0021795 cerebral cortex cell migration 24 5.577372
GO:0006195 purine nucleotide catabolic process 253 5.575681
GO:0060627 regulation of vesicle-mediated transport 150 5.574303
GO:0050807 regulation of synapse organization 32 5.572906
GO:0050772 positive regulation of axonogenesis 43 5.569386
GO:2000145 regulation of cell motility 289 5.568424
GO:0051438 regulation of ubiquitin-protein ligase activity 93 5.567737
GO:0001975 response to amphetamine 30 5.561592
GO:0072511 divalent inorganic cation transport 154 5.558961
GO:0030323 respiratory tube development 127 5.555406
GO:0048016 inositol phosphate-mediated signaling 61 5.553819
GO:0016202 regulation of striated muscle tissue development 68 5.552338
GO:0051437 positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 72 5.531177
GO:0034339 regulation of transcription from RNA polymerase II promoter by nuclear hormone receptor 60 5.52918
GO:0051352 negative regulation of ligase activity 72 5.528868
GO:0051444 negative regulation of ubiquitin-protein ligase activity 72 5.528868
GO:0060042 retina morphogenesis in camera-type eye 29 5.528128
GO:0043254 regulation of protein complex assembly 146 5.516154
GO:0032869 cellular response to insulin stimulus 181 5.511666
GO:0021915 neural tube development 96 5.498347
GO:0048754 branching morphogenesis of a tube 113 5.49733
GO:0040007 growth 269 5.493695
GO:0001662 behavioral fear response 13 5.487429
GO:0051051 negative regulation of transport 211 5.480732
GO:0046058 cAMP metabolic process 26 5.458384
GO:0009150 purine ribonucleotide metabolic process 327 5.449885
GO:0051351 positive regulation of ligase activity 83 5.435254
GO:0030879 mammary gland development 99 5.434785
GO:0051056 regulation of small GTPase mediated signal transduction 338 5.427261
GO:0007413 axonal fasciculation 11 5.418755
GO:0001649 osteoblast differentiation 56 5.414422
GO:0010565 regulation of cellular ketone metabolic process 141 5.409074
GO:0051436 negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 67 5.403797
GO:0022037 metencephalon development 58 5.397934
GO:0007623 circadian rhythm 66 5.395478
GO:0001558 regulation of cell growth 262 5.388214
GO:0042472 inner ear morphogenesis 72 5.384556
GO:0043266 regulation of potassium ion transport 15 5.383868
GO:0030036 actin cytoskeleton organization 265 5.363417
GO:0006470 protein dephosphorylation 130 5.355997
GO:0048640 negative regulation of developmental growth 20 5.352237
GO:0072523 purine-containing compound catabolic process 259 5.352036
GO:0006814 sodium ion transport 126 5.348837
GO:0009416 response to light stimulus 162 5.339915
GO:0042471 ear morphogenesis 88 5.339259
GO:0014031 mesenchymal cell development 76 5.32897
GO:0007599 hemostasis 495 5.328864
GO:0061138 morphogenesis of a branching epithelium 121 5.322157
GO:0046887 positive regulation of hormone secretion 59 5.315143
GO:0021799 cerebral cortex radially oriented cell migration 12 5.309124
GO:0030326 embryonic limb morphogenesis 96 5.308962
GO:0035113 embryonic appendage morphogenesis 96 5.308962
GO:0042770 signal transduction in response to DNA damage 111 5.307052
GO:2000602 regulation of interphase of mitotic cell cycle 121 5.303105
GO:0031397 negative regulation of protein ubiquitination 90 5.297246
GO:0021549 cerebellum development 53 5.294593
GO:0001944 vasculature development 321 5.294051
GO:0030111 regulation of Wnt receptor signaling pathway 141 5.282443
GO:0009203 ribonucleoside triphosphate catabolic process 225 5.281018
GO:0009207 purine ribonucleoside triphosphate catabolic process 225 5.281018
GO:0045137 development of primary sexual characteristics 198 5.278508
GO:0007596 blood coagulation 491 5.274629
GO:0050817 coagulation 491 5.274629
GO:0008285 negative regulation of cell proliferation 438 5.267307
GO:0030308 negative regulation of cell growth 126 5.264958
GO:0030522 intracellular receptor mediated signaling pathway 115 5.251711
GO:0051439 regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 78 5.248817
GO:0045792 negative regulation of cell size 133 5.243118
GO:0051047 positive regulation of secretion 175 5.232363
GO:0060688 regulation of morphogenesis of a branching structure 41 5.22628
GO:0032844 regulation of homeostatic process 182 5.216519
GO:0009146 purine nucleoside triphosphate catabolic process 226 5.208691
GO:2000045 regulation of G1/S transition of mitotic cell cycle 87 5.207598
GO:0051963 regulation of synaptogenesis 24 5.206849
GO:0007158 neuron cell-cell adhesion 11 5.204248
GO:0040013 negative regulation of locomotion 101 5.203235
GO:0009259 ribonucleotide metabolic process 336 5.201859
GO:0060548 negative regulation of cell death 500 5.200521
GO:0009154 purine ribonucleotide catabolic process 230 5.19816
GO:0007172 signal complex assembly 24 5.197718
GO:0051493 regulation of cytoskeleton organization 196 5.185596
GO:0048704 embryonic skeletal system morphogenesis 67 5.179698
GO:0021772 olfactory bulb development 24 5.178744
GO:0021988 olfactory lobe development 24 5.178744
GO:0050679 positive regulation of epithelial cell proliferation 91 5.176707
GO:0009261 ribonucleotide catabolic process 232 5.176486
GO:0043113 receptor clustering 16 5.1697
GO:0032446 protein modification by small protein conjugation 342 5.169047
GO:0021675 nerve development 49 5.164674
GO:0014014 negative regulation of gliogenesis 26 5.159096
GO:0007628 adult walking behavior 19 5.158771
GO:0021872 forebrain generation of neurons 27 5.156219
GO:0051340 regulation of ligase activity 97 5.154989
GO:0008088 axon cargo transport 14 5.148585
GO:0061061 muscle structure development 306 5.139087
GO:0051952 regulation of amine transport 45 5.136107
GO:0009166 nucleotide catabolic process 270 5.134041
GO:0006820 anion transport 146 5.133874
GO:0002793 positive regulation of peptide secretion 40 5.111541
GO:0031329 regulation of cellular catabolic process 343 5.106366
GO:0009143 nucleoside triphosphate catabolic process 229 5.104144
GO:0007243 intracellular protein kinase cascade 398 5.085138
GO:0023014 signal transduction via phosphorylation event 398 5.085138
GO:0016311 dephosphorylation 145 5.070608
GO:0072521 purine-containing compound metabolic process 426 5.067063
GO:0030509 BMP signaling pathway 45 5.05878
GO:0019233 sensory perception of pain 39 5.049618
GO:0045778 positive regulation of ossification 36 5.043877
GO:0007210 serotonin receptor signaling pathway 13 5.039535
GO:0034332 adherens junction organization 38 5.031421
GO:0014048 regulation of glutamate secretion 16 5.022308
GO:0031398 positive regulation of protein ubiquitination 113 5.019486
GO:0042698 ovulation cycle 97 5.018789
GO:0016567 protein ubiquitination 321 5.013754
GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process 295 5.013273
GO:0034656 nucleobase, nucleoside and nucleotide catabolic process 295 5.013273
GO:0021779 oligodendrocyte cell fate commitment 6 5.002226
GO:0034762 regulation of transmembrane transport 178 4.988209
GO:0035148 tube formation 79 4.984109
GO:2000021 regulation of ion homeostasis 98 4.983128
GO:0045669 positive regulation of osteoblast differentiation 38 4.978994
GO:0001838 embryonic epithelial tube formation 72 4.970059
GO:0042490 mechanoreceptor differentiation 30 4.966687
GO:0007212 dopamine receptor signaling pathway 17 4.9655
GO:0035235 ionotropic glutamate receptor signaling pathway 10 4.964734
GO:0048863 stem cell differentiation 60 4.956634
GO:0048814 regulation of dendrite morphogenesis 29 4.94963
GO:0021895 cerebral cortex neuron differentiation 17 4.943233
GO:0016568 chromatin modification 384 4.942534
GO:0008286 insulin receptor signaling pathway 138 4.912875
GO:0021879 forebrain neuron differentiation 18 4.905911
GO:0008406 gonad development 177 4.89992
GO:0048488 synaptic vesicle endocytosis 16 4.897555
GO:0045927 positive regulation of growth 119 4.892035
GO:0032271 regulation of protein polymerization 89 4.890701
GO:0007618 mating 30 4.888553
GO:0021515 cell differentiation in spinal cord 34 4.887982
GO:0030029 actin filament-based process 304 4.87647
GO:0030177 positive regulation of Wnt receptor signaling pathway 54 4.874355
GO:0014070 response to organic cyclic compound 216 4.873286
GO:0016055 Wnt receptor signaling pathway 150 4.871346
GO:0072175 epithelial tube formation 73 4.865807
GO:0060429 epithelium development 409 4.857726
GO:0072001 renal system development 134 4.837211
GO:0071804 cellular potassium ion transport 39 4.836566
GO:0071805 potassium ion transmembrane transport 39 4.836566
GO:0008543 fibroblast growth factor receptor signaling pathway 78 4.829142
GO:0048589 developmental growth 151 4.820693
GO:0090277 positive regulation of peptide hormone secretion 39 4.815581
GO:0032229 negative regulation of synaptic transmission, GABAergic 8 4.811651
GO:0000209 protein polyubiquitination 156 4.790288
GO:0043069 negative regulation of programmed cell death 485 4.782307
GO:0021778 oligodendrocyte cell fate specification 5 4.776081
GO:0021780 glial cell fate specification 5 4.776081
GO:0009880 embryonic pattern specification 49 4.774001
GO:0002053 positive regulation of mesenchymal cell proliferation 30 4.771603
GO:0046578 regulation of Ras protein signal transduction 243 4.771078
GO:0001568 blood vessel development 295 4.753118
GO:0033043 regulation of organelle organization 357 4.74737
GO:0042692 muscle cell differentiation 167 4.746075
GO:0016331 morphogenesis of embryonic epithelium 90 4.745634
GO:0032272 negative regulation of protein polymerization 41 4.73149
GO:0043408 regulation of MAPKKK cascade 243 4.720539
GO:0060537 muscle tissue development 168 4.707969
GO:0071377 cellular response to glucagon stimulus 36 4.698723
GO:0002089 lens morphogenesis in camera-type eye 19 4.696817
GO:0008283 cell proliferation 470 4.674389
GO:0051271 negative regulation of cellular component movement 93 4.655834
GO:0014706 striated muscle tissue development 155 4.650349
GO:0009743 response to carbohydrate stimulus 112 4.645699
GO:0031098 stress-activated protein kinase signaling cascade 112 4.642733
GO:0051216 cartilage development 102 4.636695
GO:0060420 regulation of heart growth 19 4.636462
GO:0006366 transcription from RNA polymerase II promoter 324 4.623088
GO:0022602 ovulation cycle process 88 4.612574
GO:0033674 positive regulation of kinase activity 325 4.609549
GO:0048514 blood vessel morphogenesis 245 4.605714
GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile 193 4.601484
GO:0000398 nuclear mRNA splicing, via spliceosome 193 4.601484
GO:0021983 pituitary gland development 36 4.59723
GO:0001657 ureteric bud development 77 4.592951
GO:0006511 ubiquitin-dependent protein catabolic process 317 4.586846
GO:0055123 digestive system development 92 4.580946
GO:0051480 cytosolic calcium ion homeostasis 136 4.57749
GO:0003407 neural retina development 24 4.571829
GO:0035137 hindlimb morphogenesis 33 4.566105
GO:0010464 regulation of mesenchymal cell proliferation 33 4.557711
GO:0048024 regulation of nuclear mRNA splicing, via spliceosome 24 4.557409
GO:0046660 female sex differentiation 99 4.524514
GO:0043271 negative regulation of ion transport 33 4.462227
GO:0010880 regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum 6 4.453515
GO:0032970 regulation of actin filament-based process 135 4.433652
GO:0043267 negative regulation of potassium ion transport 6 4.396581
GO:0060828 regulation of canonical Wnt receptor signaling pathway 99 4.357194
GO:0042493 response to drug 340 4.287295
GO:0060081 membrane hyperpolarization 13 4.712634
GO:0060134 prepulse inhibition 13 4.660942
GO:0045667 regulation of osteoblast differentiation 70 5.276795
GO:0051494 negative regulation of cytoskeleton organization 70 5.138999
GO:0090263 positive regulation of canonical Wnt receptor signaling pathway 40 4.907775
GO:0060384 innervation 7 5.223292
GO:0051967 negative regulation of synaptic transmission, glutamatergic 7 5.074092
GO:0048709 oligodendrocyte differentiation 43 4.361496
GO:0033500 carbohydrate homeostasis 73 4.333004
GO:0042593 glucose homeostasis 73 4.333004
GO:0014020 primary neural tube formation 47 4.638864
GO:0060606 tube closure 47 4.526713
GO:0048565 digestive tract development 84 4.452415
GO:0032956 regulation of actin cytoskeleton organization 131 4.670187
GO:0031145 anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process 80 4.800977
GO:0001841 neural tube formation 57 4.752736
GO:0006887 exocytosis 198 4.387096
GO:0060291 long-term synaptic potentiation 11 4.764342
GO:0021889 olfactory bulb interneuron differentiation 11 4.631602
GO:0021952 central nervous system projection neuron axonogenesis 10 4.799712
GO:0010738 regulation of protein kinase A signaling cascade 10 4.402295
GO:0001822 kidney development 127 4.62279
GO:0043632 modification-dependent macromolecule catabolic process 327 4.046003
GO:0000375 RNA splicing, via transesterification reactions 199 4.713436
GO:0048545 response to steroid hormone stimulus 298 4.000933
GO:0044270 cellular nitrogen compound catabolic process 321 4.235153
GO:0050954 sensory perception of mechanical stimulus 105 4.578027
GO:0050953 sensory perception of light stimulus 202 4.640946
GO:0045860 positive regulation of protein kinase activity 312 4.332784
GO:0007601 visual perception 201 4.592146
GO:0010976 positive regulation of neuron projection development 37 4.375433
GO:0001837 epithelial to mesenchymal transition 37 4.351023
GO:0019098 reproductive behavior 19 4.28951
GO:0048713 regulation of oligodendrocyte differentiation 19 4.097254
GO:0045773 positive regulation of axon extension 22 4.587138
GO:0030325 adrenal gland development 22 4.496061
GO:0042417 dopamine metabolic process 22 4.462858
GO:0045859 regulation of protein kinase activity 485 4.241316
GO:0000381 regulation of alternative nuclear mRNA splicing, via spliceosome 15 4.876978
GO:0008380 RNA splicing 297 4.049313
GO:0030517 negative regulation of axon extension 13 4.402187
GO:0021955 central nervous system neuron axonogenesis 13 4.346016
GO:0001963 synaptic transmission, dopaminergic 13 4.315806
GO:0006874 cellular calcium ion homeostasis 194 4.329308
GO:2000146 negative regulation of cell motility 88 4.354969
GO:0048469 cell maturation 89 4.535231
GO:0043062 extracellular structure organization 179 4.198279
GO:0009187 cyclic nucleotide metabolic process 48 5.718645
GO:0001708 cell fate specification 48 4.919698
GO:0006397 mRNA processing 378 4.323247
GO:0051248 negative regulation of protein metabolic process 263 4.516918
GO:0031056 regulation of histone modification 40 4.450257
GO:0046700 heterocycle catabolic process 319 4.522181
GO:2000177 regulation of neural precursor cell proliferation 31 4.753424
GO:0055074 calcium ion homeostasis 201 4.070086
GO:0016198 axon choice point recognition 7 4.456483
GO:0040019 positive regulation of embryonic development 7 4.321434
GO:0007605 sensory perception of sound 97 4.188218
GO:0032230 positive regulation of synaptic transmission, GABAergic 9 4.387065
GO:0021892 cerebral cortex GABAergic interneuron differentiation 9 4.351026
GO:0006821 chloride transport 61 4.2814
GO:0016339 calcium-dependent cell-cell adhesion 24 4.252781
GO:0045822 negative regulation of heart contraction 12 4.602702
GO:0072503 cellular divalent inorganic cation homeostasis 200 4.028135
GO:0010459 negative regulation of heart rate 5 4.289562
GO:0007018 microtubule-based movement 120 4.030915
GO:0051347 positive regulation of transferase activity 334 4.410767
GO:0009798 axis specification 72 4.698363
GO:0042551 neuron maturation 21 4.910088
GO:0045216 cell-cell junction organization 100 4.100703
GO:0032583 regulation of gene-specific transcription 97 4.413146
GO:0010817 regulation of hormone levels 192 4.264653
GO:0001656 metanephros development 57 4.445987
GO:0030518 steroid hormone receptor signaling pathway 68 4.039843
GO:0032147 activation of protein kinase activity 148 4.207743
GO:0008037 cell recognition 64 4.163793
GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity 10 4.192246
GO:0014073 response to tropane 23 4.36446
GO:0042220 response to cocaine 23 4.36446
GO:0043576 regulation of respiratory gaseous exchange 15 4.459213
GO:0051580 regulation of neurotransmitter uptake 9 4.224982
GO:0005513 detection of calcium ion 9 4.218452
GO:0046326 positive regulation of glucose import 25 4.132007
GO:0043484 regulation of RNA splicing 42 4.175744
GO:0032269 negative regulation of cellular protein metabolic process 252 3.991648
GO:0045926 negative regulation of growth 158 4.524974
GO:0043066 negative regulation of apoptosis 480 4.611772
GO:0045686 negative regulation of glial cell differentiation 20 4.543008
GO:0010771 negative regulation of cell morphogenesis involved in differentiation 12 4.181293
GO:0019941 modification-dependent protein catabolic process 324 4.216454
GO:0046879 hormone secretion 46 4.138256
GO:0003073 regulation of systemic arterial blood pressure 46 4.07491
GO:0060021 palate development 57 4.296823
GO:0051592 response to calcium ion 77 4.3051
GO:0050885 neuromuscular process controlling balance 37 4.066272
GO:0006875 cellular metal ion homeostasis 271 3.934114
GO:0014015 positive regulation of gliogenesis 26 4.339058
GO:0031111 negative regulation of microtubule polymerization or depolymerization 23 4.299683
GO:0030155 regulation of cell adhesion 194 4.062674
GO:0035019 somatic stem cell maintenance 26 4.125948
GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity 9 4.580293
GO:0006198 cAMP catabolic process 9 4.496052
GO:0090102 cochlea development 21 4.343714
GO:0021782 glial cell development 55 4.264489
GO:0051606 detection of stimulus 174 4.039113
GO:0006688 glycosphingolipid biosynthetic process 14 4.211897
GO:0048641 regulation of skeletal muscle tissue development 37 4.028836
GO:0010522 regulation of calcium ion transport into cytosol 37 4.016413
GO:0022010 central nervous system myelination 11 4.275027
GO:0032291 axon ensheathment in central nervous system 11 4.275027
GO:0043112 receptor metabolic process 52 4.32139
GO:0042058 regulation of epidermal growth factor receptor signaling pathway 59 4.151748
GO:0048864 stem cell development 47 4.158154
GO:0051153 regulation of striated muscle cell differentiation 38 4.532165
GO:0051090 regulation of sequence-specific DNA binding transcription factor activity 269 4.018282
GO:0090046 regulation of transcription regulator activity 269 4.018282
GO:0009582 detection of abiotic stimulus 63 4.610124
GO:0021542 dentate gyrus development 8 4.353849
GO:0033124 regulation of GTP catabolic process 193 4.070434
GO:0000082 G1/S transition of mitotic cell cycle 149 3.847329
GO:0014037 Schwann cell differentiation 15 4.227681
GO:0003151 outflow tract morphogenesis 23 5.089254
GO:0014072 response to isoquinoline alkaloid 23 5.04018
GO:0043278 response to morphine 23 5.04018
GO:0060113 inner ear receptor cell differentiation 28 4.179707
GO:0044257 cellular protein catabolic process 340 3.744671
GO:0060349 bone morphogenesis 48 4.15415
GO:0051968 positive regulation of synaptic transmission, glutamatergic 9 4.136264
GO:0045161 neuronal ion channel clustering 9 4.130573
GO:0045793 positive regulation of cell size 81 4.12246
GO:0045995 regulation of embryonic development 57 4.210164
GO:0040014 regulation of multicellular organism growth 57 4.206811
GO:0043547 positive regulation of GTPase activity 139 4.760017
GO:0050433 regulation of catecholamine secretion 32 4.258552
GO:0051048 negative regulation of secretion 99 3.920262
GO:0007519 skeletal muscle tissue development 80 3.892701
GO:0046324 regulation of glucose import 35 4.083193
GO:0021516 dorsal spinal cord development 18 4.236489
GO:0006376 mRNA splice site selection 18 4.226114
GO:0021587 cerebellum morphogenesis 25 3.980104
GO:0014059 regulation of dopamine secretion 17 4.401078
GO:0021575 hindbrain morphogenesis 29 4.103792
GO:0090092 regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 119 4.103713
GO:0045787 positive regulation of cell cycle 90 3.910641
GO:0051481 reduction of cytosolic calcium ion concentration 6 4.060904
GO:0055065 metal ion homeostasis 282 3.76883
GO:0044419 interspecies interaction between organisms 355 4.098294
GO:0018107 peptidyl-threonine phosphorylation 21 4.284368
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway 72 4.205068
GO:0010562 positive regulation of phosphorus metabolic process 221 3.798846
GO:0045937 positive regulation of phosphate metabolic process 221 3.798846
GO:0061351 neural precursor cell proliferation 35 4.012318
GO:0007617 mating behavior 15 4.114345
GO:0031115 negative regulation of microtubule polymerization 7 4.17232
GO:0048048 embryonic eye morphogenesis 26 4.027997
GO:0032102 negative regulation of response to external stimulus 88 4.093035
GO:0035023 regulation of Rho protein signal transduction 139 4.185908
GO:0055024 regulation of cardiac muscle tissue development 21 4.536988
GO:0033044 regulation of chromosome organization 69 4.144643
GO:0072384 organelle transport along microtubule 17 4.196783
GO:0042475 odontogenesis of dentine-containing tooth 44 4.15484
GO:0003214 cardiac left ventricle morphogenesis 8 4.283019
GO:0060070 canonical Wnt receptor signaling pathway 61 3.992032
GO:0009914 hormone transport 50 4.034127
GO:0072507 divalent inorganic cation homeostasis 208 3.860732
GO:0009755 hormone-mediated signaling pathway 31 4.127156
GO:0045776 negative regulation of blood pressure 31 4.108323
GO:0030307 positive regulation of cell growth 76 3.976404
GO:0055117 regulation of cardiac muscle contraction 14 4.157389
GO:0001942 hair follicle development 64 3.89862
GO:0022404 molting cycle process 64 3.89862
GO:0022405 hair cycle process 64 3.89862
GO:0042303 molting cycle 67 3.821058
GO:0042633 hair cycle 67 3.821058
GO:0008589 regulation of smoothened signaling pathway 38 4.064119
GO:0051603 proteolysis involved in cellular protein catabolic process 334 3.859887
GO:0043087 regulation of GTPase activity 191 4.186951
GO:0048265 response to pain 18 4.165167
GO:0050680 negative regulation of epithelial cell proliferation 65 3.987361
GO:0040034 regulation of development, heterochronic 8 4.219331
GO:0048505 regulation of timing of cell differentiation 8 4.219331
GO:0019827 stem cell maintenance 45 4.410795
GO:0002087 regulation of respiratory gaseous exchange by neurological system process 10 3.985152
GO:0003205 cardiac chamber development 69 3.999755
GO:0009953 dorsal/ventral pattern formation 75 4.360367
GO:0060736 prostate gland growth 11 4.156585
GO:0051403 stress-activated MAPK cascade 53 4.103605
GO:0048521 negative regulation of behavior 21 4.122681
GO:0010828 positive regulation of glucose transport 28 4.618083
GO:0048813 dendrite morphogenesis 20 4.328663
GO:0046661 male sex differentiation 106 3.815199
GO:0002062 chondrocyte differentiation 29 3.891188
GO:0002088 lens development in camera-type eye 46 4.598301
GO:0001843 neural tube closure 46 4.479575
GO:0007265 Ras protein signal transduction 124 3.768432
GO:0070646 protein modification by small protein removal 66 3.89848
GO:0045986 negative regulation of smooth muscle contraction 5 4.107384
GO:0007204 elevation of cytosolic calcium ion concentration 121 3.726658
GO:0055021 regulation of cardiac muscle tissue growth 17 4.040919
GO:0044089 positive regulation of cellular component biogenesis 13 3.968984
GO:0021696 cerebellar cortex morphogenesis 18 3.887839
GO:0051329 interphase of mitotic cell cycle 304 3.572073
GO:0048934 peripheral nervous system neuron differentiation 10 3.882032
GO:0048935 peripheral nervous system neuron development 10 3.882032
GO:0001659 temperature homeostasis 19 3.783986
GO:0045767 regulation of anti-apoptosis 48 3.811739
GO:0051240 positive regulation of multicellular organismal process 386 3.641404
GO:0030336 negative regulation of cell migration 86 4.310881
GO:0048742 regulation of skeletal muscle fiber development 27 3.873915
GO:0043161 proteasomal ubiquitin-dependent protein catabolic process 159 3.662382
GO:0000186 activation of MAPKK activity 43 3.819452
GO:0021871 forebrain regionalization 17 3.974635
GO:0009895 negative regulation of catabolic process 56 3.662141
GO:0070848 response to growth factor stimulus 88 3.896965
GO:0009991 response to extracellular stimulus 348 3.521464
GO:0048665 neuron fate specification 22 4.050673
GO:0030003 cellular cation homeostasis 297 3.542641
GO:0007530 sex determination 20 3.908095
GO:0001754 eye photoreceptor cell differentiation 32 3.927733
GO:0030811 regulation of nucleotide catabolic process 214 3.65365
GO:0033121 regulation of purine nucleotide catabolic process 214 3.65365
GO:0018210 peptidyl-threonine modification 24 3.942372
GO:0060538 skeletal muscle organ development 86 3.712363
GO:0008584 male gonad development 86 3.705114
GO:0048483 autonomic nervous system development 37 3.720914
GO:0003206 cardiac chamber morphogenesis 61 3.92668
GO:0030178 negative regulation of Wnt receptor signaling pathway 83 3.756556
GO:0051279 regulation of release of sequestered calcium ion into cytosol 22 3.983211
GO:0046888 negative regulation of hormone secretion 41 3.822321
GO:0042327 positive regulation of phosphorylation 213 3.675661
GO:0060004 reflex 8 3.979967
GO:0010675 regulation of cellular carbohydrate metabolic process 61 3.781579
GO:0061180 mammary gland epithelium development 41 3.804282
GO:0033762 response to glucagon stimulus 46 4.224774
GO:0002076 osteoblast development 15 3.873074
GO:0008217 regulation of blood pressure 118 3.702977
GO:0003208 cardiac ventricle morphogenesis 44 3.856668
GO:0051149 positive regulation of muscle cell differentiation 44 4.644516
GO:0021545 cranial nerve development 35 3.772869
GO:0030238 male sex determination 9 3.972365
GO:0048715 negative regulation of oligodendrocyte differentiation 10 3.74872
GO:0003357 noradrenergic neuron differentiation 5 3.83684
GO:0006109 regulation of carbohydrate metabolic process 62 3.895715
GO:0048268 clathrin coat assembly 6 3.858807
GO:0021535 cell migration in hindbrain 6 3.855269
GO:0003013 circulatory system process 211 3.692789
GO:0046546 development of primary male sexual characteristics 100 3.705845
GO:0034199 activation of protein kinase A activity 16 3.943761
GO:0003338 metanephros morphogenesis 16 3.877587
GO:0051705 behavioral interaction between organisms 38 3.850522
GO:0060348 bone development 66 4.321071
GO:0043401 steroid hormone mediated signaling pathway 15 3.770855
GO:0060119 inner ear receptor cell development 15 3.767084
GO:0018958 phenol-containing compound metabolic process 54 3.699393
GO:0060603 mammary gland duct morphogenesis 24 3.809558
GO:0002027 regulation of heart rate 29 3.739831
GO:0060350 endochondral bone morphogenesis 27 3.742794
GO:0048708 astrocyte differentiation 16 3.835713
GO:0010632 regulation of epithelial cell migration 16 3.806251
GO:0007517 muscle organ development 201 3.484092
GO:0001704 formation of primary germ layer 60 3.604466
GO:0000245 spliceosome assembly 39 3.802485
GO:0009214 cyclic nucleotide catabolic process 11 3.777134
GO:0001678 cellular glucose homeostasis 21 3.925757
GO:0001503 ossification 146 3.904332
GO:0048596 embryonic camera-type eye morphogenesis 21 3.871923
GO:0034284 response to monosaccharide stimulus 94 3.559783
GO:0046716 muscle cell homeostasis 14 3.963531
GO:0046530 photoreceptor cell differentiation 33 3.794708
GO:0045981 positive regulation of nucleotide metabolic process 37 3.566241
GO:0021533 cell differentiation in hindbrain 16 3.756467
GO:0006369 termination of RNA polymerase II transcription 44 3.611194
GO:0043623 cellular protein complex assembly 179 3.613591
GO:0003231 cardiac ventricle development 58 3.635773
GO:0090009 primitive streak formation 9 3.919462
GO:0008015 blood circulation 210 3.685473
GO:0030801 positive regulation of cyclic nucleotide metabolic process 36 3.712825
GO:0010498 proteasomal protein catabolic process 160 3.649507
GO:0010035 response to inorganic substance 328 3.581512
GO:0021891 olfactory bulb interneuron development 8 3.815232
GO:0061053 somite development 52 3.618666
GO:0090278 negative regulation of peptide hormone secretion 25 3.710924
GO:0051101 regulation of DNA binding 45 3.527872
GO:0051325 interphase 318 3.506862
GO:0051930 regulation of sensory perception of pain 18 3.664003
GO:0051931 regulation of sensory perception 18 3.664003
GO:0048712 negative regulation of astrocyte differentiation 9 3.766566
GO:0030815 negative regulation of cAMP metabolic process 9 3.746195
GO:0030818 negative regulation of cAMP biosynthetic process 9 3.746195
GO:0003085 negative regulation of systemic arterial blood pressure 9 3.699117
GO:0006582 melanin metabolic process 9 3.688819
GO:0042438 melanin biosynthetic process 9 3.688819
GO:0010977 negative regulation of neuron projection development 23 3.797775
GO:0060059 embryonic retina morphogenesis in camera-type eye 8 3.733457
GO:0007274 neuromuscular synaptic transmission 16 3.683626
GO:0035249 synaptic transmission, glutamatergic 16 3.664051
GO:0030804 positive regulation of cyclic nucleotide biosynthetic process 34 3.738452
GO:0030810 positive regulation of nucleotide biosynthetic process 34 3.738452
GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter 96 4.527926
GO:0060395 SMAD protein signal transduction 15 3.680082
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis 5 3.651135
GO:0015711 organic anion transport 62 3.741663
GO:0050906 detection of stimulus involved in sensory perception 83 3.544312
GO:0008585 female gonad development 83 3.517483
GO:0030100 regulation of endocytosis 89 3.316576
GO:2000179 positive regulation of neural precursor cell proliferation 19 3.615667
GO:0007405 neuroblast proliferation 19 3.562815
GO:0009247 glycolipid biosynthetic process 16 3.587214
GO:0017158 regulation of calcium ion-dependent exocytosis 22 3.693185
GO:0060080 regulation of inhibitory postsynaptic membrane potential 9 3.573404
GO:0060992 response to fungicide 9 3.547036
GO:0045637 regulation of myeloid cell differentiation 105 3.478521
GO:0016188 synaptic vesicle maturation 7 3.707685
GO:0044065 regulation of respiratory system process 11 3.653401
GO:0070371 ERK1 and ERK2 cascade 15 3.652546
GO:0045879 negative regulation of smoothened signaling pathway 16 3.545588
GO:0000216 M/G1 transition of mitotic cell cycle 79 3.551677
GO:0046676 negative regulation of insulin secretion 23 3.607922
GO:0060560 developmental growth involved in morphogenesis 53 3.5525
GO:0051058 negative regulation of small GTPase mediated signal transduction 27 3.567413
GO:0060425 lung morphogenesis 27 3.5563
GO:0060993 kidney morphogenesis 27 3.543086
GO:0043268 positive regulation of potassium ion transport 6 3.727804
GO:0032330 regulation of chondrocyte differentiation 28 3.669503
GO:0010639 negative regulation of organelle organization 136 3.455554
GO:0006096 glycolysis 45 3.434097
GO:0001892 embryonic placenta development 53 3.530401
GO:0003281 ventricular septum development 24 3.593451
GO:0031396 regulation of protein ubiquitination 151 4.388434
GO:0009583 detection of light stimulus 41 3.485995
GO:0001525 angiogenesis 188 3.305094
GO:0071503 response to heparin 5 3.5824
GO:0014075 response to amine stimulus 83 3.367877
GO:0060402 calcium ion transport into cytosol 29 3.629255
GO:0030816 positive regulation of cAMP metabolic process 29 3.621223
GO:0030819 positive regulation of cAMP biosynthetic process 29 3.621223
GO:0001934 positive regulation of protein phosphorylation 194 3.580825
GO:0006584 catecholamine metabolic process 38 3.44888
GO:0042476 odontogenesis 71 3.472528
GO:0014033 neural crest cell differentiation 49 3.439655
GO:0043242 negative regulation of protein complex disassembly 42 3.626291
GO:0007179 transforming growth factor beta receptor signaling pathway 64 3.418665
GO:0035051 cardiac cell differentiation 54 3.34405
GO:0015698 inorganic anion transport 94 4.907219
GO:0046545 development of primary female sexual characteristics 94 4.484631
GO:0048566 embryonic digestive tract development 29 3.499481
GO:0009954 proximal/distal pattern formation 21 3.646682
GO:0048670 regulation of collateral sprouting 7 3.623287
GO:0034330 cell junction organization 155 3.499887
GO:0010627 regulation of intracellular protein kinase cascade 444 3.269402
GO:0009746 response to hexose stimulus 92 3.381765
GO:0072298 regulation of metanephric glomerulus development 6 3.628041
GO:0048710 regulation of astrocyte differentiation 15 3.537413
GO:0010594 regulation of endothelial cell migration 51 3.577974
GO:0010719 negative regulation of epithelial to mesenchymal transition 9 3.442152
GO:0032332 positive regulation of chondrocyte differentiation 14 3.687913
GO:0060412 ventricular septum morphogenesis 14 3.67008
GO:0000077 DNA damage checkpoint 119 3.480522
GO:0010906 regulation of glucose metabolic process 52 3.430487
GO:0048546 digestive tract morphogenesis 41 3.449518
GO:0021522 spinal cord motor neuron differentiation 17 3.501562
GO:0071326 cellular response to monosaccharide stimulus 17 3.479612
GO:0071331 cellular response to hexose stimulus 17 3.479612
GO:0071333 cellular response to glucose stimulus 17 3.479612
GO:0009190 cyclic nucleotide biosynthetic process 30 3.589042
GO:0002792 negative regulation of peptide secretion 26 3.463033
GO:0017156 calcium ion-dependent exocytosis 26 3.414702
GO:0045768 positive regulation of anti-apoptosis 39 3.447088
GO:0032024 positive regulation of insulin secretion 32 3.565448
GO:0007213 muscarinic acetylcholine receptor signaling pathway 12 3.689926
GO:0051962 positive regulation of nervous system development 12 3.568717
GO:0051965 positive regulation of synaptogenesis 12 3.568717
GO:0051146 striated muscle cell differentiation 110 3.172336
GO:0031557 induction of programmed cell death in response to chemical stimulus 6 3.566039
GO:0010563 negative regulation of phosphorus metabolic process 78 3.355583
GO:0045936 negative regulation of phosphate metabolic process 78 3.355583
GO:0007584 response to nutrient 223 3.312081
GO:0010676 positive regulation of cellular carbohydrate metabolic process 28 3.499698
GO:0045913 positive regulation of carbohydrate metabolic process 28 3.499698
GO:0021695 cerebellar cortex development 28 3.457728
GO:0010038 response to metal ion 219 3.201551
GO:0071300 cellular response to retinoic acid 41 3.424037
GO:0021527 spinal cord association neuron differentiation 11 3.381081
GO:0002052 positive regulation of neuroblast proliferation 11 3.378379
GO:0030850 prostate gland development 34 3.522087
GO:0050684 regulation of mRNA processing 34 3.493095
GO:0031128 developmental induction 27 3.373865
GO:0019882 antigen processing and presentation 126 3.279091
GO:0014032 neural crest cell development 43 3.179966
GO:0033143 regulation of steroid hormone receptor signaling pathway 30 3.515657
GO:0030163 protein catabolic process 366 3.086738
GO:0050999 regulation of nitric-oxide synthase activity 30 3.460143
GO:0060401 cytosolic calcium ion transport 30 3.406088
GO:0010717 regulation of epithelial to mesenchymal transition 30 3.367367
GO:0051258 protein polymerization 49 3.085623
GO:0006913 nucleocytoplasmic transport 182 3.364796
GO:0035065 regulation of histone acetylation 19 3.209235
GO:0001976 neurological system process involved in regulation of systemic arterial blood pressure 14 3.529135
GO:0021697 cerebellar cortex formation 14 3.409464
GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway 7 3.399617
GO:0042752 regulation of circadian rhythm 32 3.300544
GO:0032880 regulation of protein localization 252 3.210572
GO:0060043 regulation of cardiac muscle cell proliferation 15 3.42309
GO:0043255 regulation of carbohydrate biosynthetic process 37 3.309982
GO:0006458 'de novo' protein folding 53 3.189681
GO:0060740 prostate gland epithelium morphogenesis 21 3.40856
GO:0061035 regulation of cartilage development 39 3.278057
GO:0043410 positive regulation of MAPKKK cascade 127 3.168294
GO:0003382 epithelial cell morphogenesis 22 3.41086
GO:0040018 positive regulation of multicellular organism growth 22 3.400823
GO:0070588 calcium ion transmembrane transport 33 3.446456
GO:0090257 regulation of muscle system process 90 3.381165
GO:0001958 endochondral ossification 16 3.411024
GO:0061039 ovum-producing ovary development 72 3.345017
GO:0001504 neurotransmitter uptake 13 3.550506
GO:0016925 protein sumoylation 13 3.47322
GO:0003279 cardiac septum development 31 3.309488
GO:0022612 gland morphogenesis 81 4.557573
GO:0033273 response to vitamin 148 3.134653
GO:0042537 benzene-containing compound metabolic process 63 3.133221
GO:0003018 vascular process in circulatory system 63 3.122505
GO:0050922 negative regulation of chemotaxis 14 3.393711
GO:0032909 regulation of transforming growth factor-beta2 production 7 3.354891
GO:0014850 response to muscle activity 7 3.345531
GO:0035303 regulation of dephosphorylation 43 3.158867
GO:0031667 response to nutrient levels 325 3.193202
GO:0016579 protein deubiquitination 55 3.302022
GO:0010810 regulation of cell-substrate adhesion 72 3.300809
GO:0035282 segmentation 69 3.327036
GO:0003207 cardiac chamber formation 8 3.555923
GO:0003211 cardiac ventricle formation 8 3.555923
GO:0009314 response to radiation 265 3.204797
GO:0031110 regulation of microtubule polymerization or depolymerization 35 3.40447
GO:0006606 protein import into nucleus 80 3.2358
GO:0010243 response to organic nitrogen 118 3.222369
GO:0010656 negative regulation of muscle cell apoptosis 11 3.298022
GO:0051241 negative regulation of multicellular organismal process 269 3.270842
GO:0045931 positive regulation of mitotic cell cycle 27 3.281084
GO:0043270 positive regulation of ion transport 67 3.14633
GO:0030514 negative regulation of BMP signaling pathway 26 3.249046
GO:0046580 negative regulation of Ras protein signal transduction 26 3.202514
GO:0045746 negative regulation of Notch signaling pathway 11 3.234687
GO:0071322 cellular response to carbohydrate stimulus 20 3.531261
GO:0051170 nuclear import 83 3.095323
GO:0071248 cellular response to metal ion 46 3.147092
GO:0045168 cell-cell signaling involved in cell fate commitment 28 3.373725
GO:0009712 catechol metabolic process 39 3.258266
GO:0034311 diol metabolic process 39 3.258266
GO:0007276 gamete generation 452 3.111232
GO:0040017 positive regulation of locomotion 178 3.059147
GO:0046113 nucleobase catabolic process 9 3.340888
GO:0045732 positive regulation of protein catabolic process 64 3.05186
GO:0007191 activation of adenylate cyclase activity by dopamine receptor signaling pathway 7 3.322726
GO:0021877 forebrain neuron fate commitment 7 3.314901
GO:0030832 regulation of actin filament length 83 3.000053
GO:0043409 negative regulation of MAPKKK cascade 66 3.119537
GO:0032526 response to retinoic acid 83 2.937048
GO:0046777 protein autophosphorylation 94 3.23005
GO:0061072 iris morphogenesis 6 3.472125
GO:0090004 positive regulation of establishment of protein localization in plasma membrane 11 3.195215
GO:0034504 protein localization to nucleus 103 3.163268
GO:0032768 regulation of monooxygenase activity 40 3.248242
GO:0045687 positive regulation of glial cell differentiation 21 3.347964
GO:0051169 nuclear transport 184 3.227254
GO:2000241 regulation of reproductive process 124 3.278869
GO:0051098 regulation of binding 124 3.241978
GO:0034329 cell junction assembly 136 3.003331
GO:0070936 protein K48-linked ubiquitination 32 3.206464
GO:0006007 glucose catabolic process 58 3.192279
GO:0007162 negative regulation of cell adhesion 58 3.169775
GO:0001701 in utero embryonic development 228 3.094037
GO:0006576 cellular biogenic amine metabolic process 117 3.18241
GO:0051602 response to electrical stimulus 26 3.187423
GO:0001756 somitogenesis 44 3.288153
GO:0048806 genitalia development 32 3.045712
GO:0050919 negative chemotaxis 10 3.43867
GO:0001661 conditioned taste aversion 5 3.480407
GO:0015872 dopamine transport 5 3.445054
GO:0010634 positive regulation of epithelial cell migration 11 3.139559
GO:0060231 mesenchymal to epithelial transition 11 3.133855
GO:0060687 regulation of branching involved in prostate gland morphogenesis 7 3.30587
GO:0021801 cerebral cortex radial glia guided migration 6 3.419052
GO:0007093 mitotic cell cycle checkpoint 125 3.137388
GO:0031113 regulation of microtubule polymerization 17 4.722799
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway 37 3.175444
GO:0010660 regulation of muscle cell apoptosis 16 3.230955
GO:0007026 negative regulation of microtubule depolymerization 16 3.225657
GO:0060174 limb bud formation 8 3.488902
GO:0033144 negative regulation of steroid hormone receptor signaling pathway 13 3.23585
GO:0045815 positive regulation of gene expression, epigenetic 13 3.232433
GO:0032413 negative regulation of ion transmembrane transporter activity 16 3.175928
GO:0006469 negative regulation of protein kinase activity 125 3.097217
GO:0030510 regulation of BMP signaling pathway 50 3.159037
GO:0009581 detection of external stimulus 76 3.040803
GO:0034130 toll-like receptor 1 signaling pathway 69 3.008302
GO:0034134 toll-like receptor 2 signaling pathway 69 3.008302
GO:0048679 regulation of axon regeneration 9 3.263192
GO:0070570 regulation of neuron projection regeneration 9 3.263192
GO:0046068 cGMP metabolic process 21 3.232862
GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback 7 3.267199
GO:0060526 prostate glandular acinus morphogenesis 7 3.219008
GO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis 7 3.219008
GO:0050974 detection of mechanical stimulus involved in sensory perception 10 3.396405
GO:0090192 regulation of glomerulus development 10 3.373754
GO:0030800 negative regulation of cyclic nucleotide metabolic process 10 3.371143
GO:0030803 negative regulation of cyclic nucleotide biosynthetic process 10 3.371143
GO:0030809 negative regulation of nucleotide biosynthetic process 10 3.371143
GO:0090101 negative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway 55 3.07017
GO:0015800 acidic amino acid transport 16 3.108534
GO:0035162 embryonic hemopoiesis 10 3.34183
GO:0018209 peptidyl-serine modification 61 3.1776
GO:0061136 regulation of proteasomal protein catabolic process 52 3.192833
GO:0031570 DNA integrity checkpoint 126 3.009721
GO:0017015 regulation of transforming growth factor beta receptor signaling pathway 59 3.037999
GO:0042462 eye photoreceptor cell development 26 3.15248
GO:0007435 salivary gland morphogenesis 26 3.146195
GO:0060442 branching involved in prostate gland morphogenesis 11 3.106142
GO:0042461 photoreceptor cell development 27 3.012784
GO:0021544 subpallium development 15 3.285617
GO:0010842 retina layer formation 7 3.210487
GO:0014065 phosphatidylinositol 3-kinase cascade 13 3.160391
GO:0051272 positive regulation of cellular component movement 179 2.947976
GO:0032320 positive regulation of Ras GTPase activity 84 3.118896
GO:0006094 gluconeogenesis 41 3.121599
GO:0021826 substrate-independent telencephalic tangential migration 6 3.29707
GO:0021843 substrate-independent telencephalic tangential interneuron migration 6 3.29707
GO:0021903 rostrocaudal neural tube patterning 12 3.293799
GO:0006937 regulation of muscle contraction 77 3.165178
GO:0033673 negative regulation of kinase activity 132 3.017326
GO:0090190 positive regulation of branching involved in ureteric bud morphogenesis 16 3.052677
GO:0042491 auditory receptor cell differentiation 16 3.032762
GO:0030520 estrogen receptor signaling pathway 16 3.022859
GO:0071559 response to transforming growth factor beta stimulus 22 3.160281
GO:0051584 regulation of dopamine uptake 6 3.18306
GO:0051940 regulation of catecholamine uptake involved in synaptic transmission 6 3.18306
GO:0072006 nephron development 40 3.102366
GO:0030837 negative regulation of actin filament polymerization 34 3.302617
GO:0032434 regulation of proteasomal ubiquitin-dependent protein catabolic process 44 3.101217
GO:0033189 response to vitamin A 97 3.063731
GO:0007369 gastrulation 96 3.042838
GO:0060393 regulation of pathway-restricted SMAD protein phosphorylation 22 3.137593
GO:0030833 regulation of actin filament polymerization 71 2.99016
GO:0008593 regulation of Notch signaling pathway 20 3.232389
GO:0030072 peptide hormone secretion 36 2.987178
GO:0045598 regulation of fat cell differentiation 47 3.200571
GO:0032350 regulation of hormone metabolic process 21 3.033646
GO:0060068 vagina development 5 3.382064
GO:0032355 response to estradiol stimulus 98 3.036126
GO:0043405 regulation of MAP kinase activity 205 2.89073
GO:0071901 negative regulation of protein serine/threonine kinase activity 77 3.000625
GO:0060850 regulation of transcription involved in cell fate commitment 10 3.251513
GO:0060065 uterus development 10 3.238364
GO:0048841 regulation of axon extension involved in axon guidance 10 3.157918
GO:0060045 positive regulation of cardiac muscle cell proliferation 10 3.127939
GO:0061008 hepaticobiliary system development 74 2.917282
GO:0071299 cellular response to vitamin A 42 3.243234
GO:0060441 epithelial tube branching involved in lung morphogenesis 16 2.984294
GO:0048332 mesoderm morphogenesis 49 2.788793
GO:0045749 negative regulation of S phase of mitotic cell cycle 10 3.026617
GO:0040023 establishment of nucleus localization 10 2.980899
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity 10 2.949453
GO:0014044 Schwann cell development 10 2.910043
GO:0060117 auditory receptor cell development 7 3.135401
GO:0035136 forelimb morphogenesis 31 3.11279
GO:0043116 negative regulation of vascular permeability 7 3.110162
GO:0072132 mesenchyme morphogenesis 7 3.09843
GO:0010664 negative regulation of striated muscle cell apoptosis 7 3.07507
GO:0010469 regulation of receptor activity 42 3.150048
GO:0042177 negative regulation of protein catabolic process 30 3.038601
GO:0045599 negative regulation of fat cell differentiation 25 3.139732
GO:0035116 embryonic hindlimb morphogenesis 25 3.091737
GO:0048096 chromatin-mediated maintenance of transcription 5 3.355683
GO:0033120 positive regulation of RNA splicing 5 3.280786
GO:0015701 bicarbonate transport 14 3.143239
GO:0051100 negative regulation of binding 49 2.702156
GO:0017145 stem cell division 18 3.191718
GO:0009950 dorsal/ventral axis specification 21 2.905646
GO:0035272 exocrine system development 37 3.056951
GO:0060512 prostate gland morphogenesis 23 3.167521
GO:0009125 nucleoside monophosphate catabolic process 16 2.92566
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process 30 3.005052
GO:0055080 cation homeostasis 337 3.143955
GO:0000084 S phase of mitotic cell cycle 114 2.919614
GO:0001890 placenta development 88 2.85796
GO:0002064 epithelial cell development 53 2.992646
GO:0051926 negative regulation of calcium ion transport 17 3.125057
GO:0031076 embryonic camera-type eye development 29 3.11865
GO:0032026 response to magnesium ion 10 2.878924
GO:0003012 muscle system process 197 2.6696
GO:0048172 regulation of short-term neuronal synaptic plasticity 8 3.239695
GO:0071363 cellular response to growth factor stimulus 68 2.99529
GO:0051591 response to cAMP 68 2.988186
GO:0007283 spermatogenesis 355 2.654074
GO:0048232 male gamete generation 355 2.654074
GO:0072273 metanephric nephron morphogenesis 12 3.121232
GO:0048738 cardiac muscle tissue development 80 2.884514
GO:0060411 cardiac septum morphogenesis 21 2.887335
GO:0001578 microtubule bundle formation 21 2.869679
GO:0045777 positive regulation of blood pressure 35 2.859099
GO:0042401 cellular biogenic amine biosynthetic process 39 2.983385
GO:0002790 peptide secretion 39 2.960071
GO:0060711 labyrinthine layer development 28 3.111973
GO:0045807 positive regulation of endocytosis 54 2.895111
GO:0022011 myelination in peripheral nervous system 8 3.206078
GO:0032292 peripheral nervous system axon ensheathment 8 3.206078
GO:0010662 regulation of striated muscle cell apoptosis 8 3.190403
GO:0009896 positive regulation of catabolic process 99 2.765424
GO:0018105 peptidyl-serine phosphorylation 51 3.021249
GO:0006940 regulation of smooth muscle contraction 39 2.896444
GO:0060443 mammary gland morphogenesis 38 2.834306
GO:0032222 regulation of synaptic transmission, cholinergic 5 3.116902
GO:0042445 hormone metabolic process 142 2.815925
GO:0071383 cellular response to steroid hormone stimulus 45 2.740037
GO:2000147 positive regulation of cell motility 170 2.822781
GO:0051781 positive regulation of cell division 45 2.720905
GO:0070169 positive regulation of biomineral tissue development 28 3.012754
GO:0051320 S phase 125 2.828121
GO:0034142 toll-like receptor 4 signaling pathway 76 2.75356
GO:0031057 negative regulation of histone modification 14 2.959342
GO:0002756 MyD88-independent toll-like receptor signaling pathway 65 2.747805
GO:0030335 positive regulation of cell migration 169 2.81428
GO:0009948 anterior/posterior axis specification 34 3.095973
GO:0007602 phototransduction 34 3.009615
GO:0002761 regulation of myeloid leukocyte differentiation 58 3.014154
GO:0043403 skeletal muscle tissue regeneration 16 2.808536
GO:0034138 toll-like receptor 3 signaling pathway 63 2.883984
GO:0008045 motor axon guidance 15 3.160028
GO:0048103 somatic stem cell division 15 3.157167
GO:0006171 cAMP biosynthetic process 15 3.134325
GO:0009749 response to glucose stimulus 86 2.899939
GO:0006833 water transport 35 2.659059
GO:0032410 negative regulation of transporter activity 22 2.89202
GO:0030521 androgen receptor signaling pathway 41 3.051937
GO:0048009 insulin-like growth factor receptor signaling pathway 13 2.891212
GO:0031112 positive regulation of microtubule polymerization or depolymerization 13 2.881335
GO:0014050 negative regulation of glutamate secretion 6 3.111249
GO:0030388 fructose 1,6-bisphosphate metabolic process 6 3.107487
GO:0021800 cerebral cortex tangential migration 6 3.077499
GO:0045639 positive regulation of myeloid cell differentiation 47 2.930915
GO:0031069 hair follicle morphogenesis 24 3.030733
GO:0000188 inactivation of MAPK activity 24 3.009887
GO:0046034 ATP metabolic process 137 2.985716
GO:0043949 regulation of cAMP-mediated signaling 9 3.014441
GO:0042738 exogenous drug catabolic process 9 2.917103
GO:0002016 regulation of blood volume by renin-angiotensin 9 2.875639
GO:0042428 serotonin metabolic process 9 2.863272
GO:0071425 hemopoietic stem cell proliferation 9 2.859783
GO:0042416 dopamine biosynthetic process 9 2.837259
GO:0051155 positive regulation of striated muscle cell differentiation 9 2.803775
GO:0016572 histone phosphorylation 9 2.797033
GO:0003156 regulation of organ formation 25 2.997159
GO:0016199 axon midline choice point recognition 5 3.068715
GO:0010741 negative regulation of intracellular protein kinase cascade 90 2.792337
GO:0033598 mammary gland epithelial cell proliferation 8 3.132873
GO:0060900 embryonic camera-type eye formation 10 2.81567
GO:0042053 regulation of dopamine metabolic process 11 2.788264
GO:0060525 prostate glandular acinus development 11 2.785659
GO:0032095 regulation of response to food 11 2.757177
GO:0060487 lung epithelial cell differentiation 13 2.846964
GO:0002072 optic cup morphogenesis involved in camera-type eye development 6 2.991673
GO:0051589 negative regulation of neurotransmitter transport 6 2.975175
GO:0071542 dopaminergic neuron differentiation 6 2.971623
GO:0000338 protein deneddylation 9 2.743414
GO:0010388 cullin deneddylation 9 2.743414
GO:0045956 positive regulation of calcium ion-dependent exocytosis 9 2.729208
GO:0007346 regulation of mitotic cell cycle 267 2.976739
GO:0002093 auditory receptor cell morphogenesis 5 3.027994
GO:0003310 pancreatic A cell differentiation 5 2.998244
GO:0048010 vascular endothelial growth factor receptor signaling pathway 21 2.770589
GO:0043627 response to estrogen stimulus 156 2.776626
GO:0048532 anatomical structure arrangement 9 2.679464
GO:0014002 astrocyte development 9 2.657339
GO:0050686 negative regulation of mRNA processing 9 2.656209
GO:0047496 vesicle transport along microtubule 9 2.650015
GO:0031124 mRNA 3'-end processing 70 2.739669
GO:0060322 head development 30 2.935703
GO:0021756 striatum development 12 2.994749
GO:0043467 regulation of generation of precursor metabolites and energy 40 2.759682
GO:0071241 cellular response to inorganic substance 53 2.846853
GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process 46 2.847376
GO:0016049 cell growth 82 2.645552
GO:0032411 positive regulation of transporter activity 25 2.781377
GO:0060324 face development 25 2.743194
GO:0010463 mesenchymal cell proliferation 9 2.632253
GO:0071295 cellular response to vitamin 51 2.722328
GO:0048871 multicellular organismal homeostasis 85 2.815288
GO:0045920 negative regulation of exocytosis 11 2.738336
GO:0060219 camera-type eye photoreceptor cell differentiation 11 2.735923
GO:0032318 regulation of Ras GTPase activity 132 2.650209
GO:0031116 positive regulation of microtubule polymerization 10 2.666963
GO:0061036 positive regulation of cartilage development 10 2.600803
GO:0016570 histone modification 203 2.754907
GO:0005979 regulation of glycogen biosynthetic process 21 2.653527
GO:0010962 regulation of glucan biosynthetic process 21 2.653527
GO:0032885 regulation of polysaccharide biosynthetic process 21 2.653527
GO:0048538 thymus development 25 2.723172
GO:0015807 L-amino acid transport 16 2.72093
GO:0045661 regulation of myoblast differentiation 16 2.698569
GO:0007565 female pregnancy 138 2.89455
GO:0007266 Rho protein signal transduction 46 2.797728
GO:0043090 amino acid import 9 2.57921
GO:0022028 tangential migration from the subventricular zone to the olfactory bulb 8 3.115915
GO:0006208 pyrimidine base catabolic process 8 3.083151
GO:0021692 cerebellar Purkinje cell layer morphogenesis 8 3.013334
GO:0021694 cerebellar Purkinje cell layer formation 8 3.013334
GO:0021702 cerebellar Purkinje cell differentiation 8 3.013334
GO:0060216 definitive hemopoiesis 8 2.973242
GO:0060158 activation of phospholipase C activity by dopamine receptor signaling pathway 8 2.965516
GO:0031114 regulation of microtubule depolymerization 17 2.923844
GO:0090189 regulation of branching involved in ureteric bud morphogenesis 17 2.883848
GO:0007216 metabotropic glutamate receptor signaling pathway 7 2.832255
GO:0021794 thalamus development 10 2.572041
GO:0015833 peptide transport 53 2.692087
GO:0016569 covalent chromatin modification 206 2.618071
GO:0006754 ATP biosynthetic process 71 2.634462
GO:0046620 regulation of organ growth 40 2.736722
GO:0072189 ureter development 7 2.706379
GO:0035067 negative regulation of histone acetylation 5 2.921239
GO:0060789 hair follicle placode formation 5 2.908853
GO:0014009 glial cell proliferation 5 2.898577
GO:0072017 distal tubule development 5 2.860663
GO:0072025 distal convoluted tubule development 5 2.860663
GO:0072221 metanephric distal convoluted tubule development 5 2.860663
GO:0072235 metanephric distal tubule development 5 2.860663
GO:0007492 endoderm development 42 2.863656
GO:0030901 midbrain development 28 2.809055
GO:0072210 metanephric nephron development 18 2.673763
GO:0060122 inner ear receptor stereocilium organization 8 2.941384
GO:0042310 vasoconstriction 14 2.837094
GO:0060479 lung cell differentiation 14 2.796296
GO:0014821 phasic smooth muscle contraction 14 2.736654
GO:0021854 hypothalamus development 14 2.73149
GO:0048843 negative regulation of axon extension involved in axon guidance 7 2.691319
GO:0043407 negative regulation of MAP kinase activity 57 2.796708
GO:0051961 negative regulation of nervous system development 5 2.840574
GO:0035265 organ growth 25 2.670361
GO:0060749 mammary gland alveolus development 11 2.633557
GO:0061377 mammary gland lobule development 11 2.633557
GO:0003254 regulation of membrane depolarization 11 2.629244
GO:0008154 actin polymerization or depolymerization 22 2.749827
GO:0072234 metanephric nephron tubule development 10 2.56454
GO:0072243 metanephric nephron epithelium development 10 2.56454
GO:0048701 embryonic cranial skeleton morphogenesis 30 2.823973
GO:0061303 cornea development in camera-type eye 6 2.874572
GO:0042321 negative regulation of circadian sleep/wake cycle, sleep 6 2.871959
GO:0042754 negative regulation of circadian rhythm 6 2.871959
GO:2000020 positive regulation of male gonad development 6 2.829964
GO:0051590 positive regulation of neurotransmitter transport 6 2.799614
GO:0043392 negative regulation of DNA binding 22 2.7126
GO:0007431 salivary gland development 29 2.795854
GO:0006942 regulation of striated muscle contraction 29 2.774149
GO:0032925 regulation of activin receptor signaling pathway 13 2.719511
GO:0021559 trigeminal nerve development 6 2.770362
GO:0070555 response to interleukin-1 51 2.678873
GO:0051386 regulation of nerve growth factor receptor signaling pathway 8 2.833744
GO:0060251 regulation of glial cell proliferation 8 2.810281
GO:0001952 regulation of cell-matrix adhesion 36 2.800335
GO:0043526 neuroprotection 25 2.609848
GO:0032881 regulation of polysaccharide metabolic process 22 2.646645
GO:0070873 regulation of glycogen metabolic process 22 2.646645
GO:0002040 sprouting angiogenesis 18 2.630089
GO:0046885 regulation of hormone biosynthetic process 16 2.688115
GO:0060123 regulation of growth hormone secretion 8 2.776831
GO:0006687 glycosphingolipid metabolic process 30 2.78993
GO:0043535 regulation of blood vessel endothelial cell migration 30 2.787815
GO:0003044 regulation of systemic arterial blood pressure mediated by a chemical signal 30 2.734061
GO:0001707 mesoderm formation 46 2.708173
GO:0072073 kidney epithelium development 30 2.70117
GO:0007219 Notch signaling pathway 55 2.715307
GO:0042326 negative regulation of phosphorylation 73 2.915829
GO:0060571 morphogenesis of an epithelial fold 11 2.580168
GO:0031558 induction of apoptosis in response to chemical stimulus 5 2.803777
GO:0014003 oligodendrocyte development 28 2.646488
GO:0051385 response to mineralocorticoid stimulus 28 2.641422
GO:0030858 positive regulation of epithelial cell differentiation 15 2.987002
GO:0001829 trophectodermal cell differentiation 15 2.980802
GO:0051953 negative regulation of amine transport 14 2.711447
GO:0048041 focal adhesion assembly 14 2.682579
GO:0060788 ectodermal placode formation 14 2.65447
GO:0071696 ectodermal placode development 14 2.65447
GO:0071697 ectodermal placode morphogenesis 14 2.65447
GO:0008211 glucocorticoid metabolic process 14 2.645377
GO:0010827 regulation of glucose transport 70 2.552577
GO:0008064 regulation of actin polymerization or depolymerization 81 2.694667
GO:0051348 negative regulation of transferase activity 140 2.685591
GO:0043525 positive regulation of neuron apoptosis 33 2.897019
GO:0048485 sympathetic nervous system development 21 2.480593
GO:0045823 positive regulation of heart contraction 21 2.475293
GO:0070167 regulation of biomineral tissue development 49 2.593788
GO:0070507 regulation of microtubule cytoskeleton organization 56 2.581847
GO:0033057 multicellular organismal reproductive behavior 12 2.907098
GO:0007498 mesoderm development 88 2.476449
GO:0014049 positive regulation of glutamate secretion 8 2.763927
GO:0051937 catecholamine transport 8 2.753442
GO:0035020 regulation of Rac protein signal transduction 13 2.559009
GO:0003209 cardiac atrium morphogenesis 13 2.547452
GO:0003230 cardiac atrium development 13 2.547452
GO:0042481 regulation of odontogenesis 17 2.853323
GO:0032386 regulation of intracellular transport 135 2.528665
GO:0042133 neurotransmitter metabolic process 25 2.564819
GO:0045785 positive regulation of cell adhesion 95 2.715459
GO:0021517 ventral spinal cord development 20 2.99957
GO:0001702 gastrulation with mouth forming second 25 2.474392
GO:0050886 endocrine process 27 2.713656
GO:0045862 positive regulation of proteolysis 58 2.637102
GO:0035335 peptidyl-tyrosine dephosphorylation 58 2.616562
GO:0060766 negative regulation of androgen receptor signaling pathway 9 2.521121
GO:0043244 regulation of protein complex disassembly 58 2.587478
GO:0045932 negative regulation of muscle contraction 12 2.849828
GO:2000178 negative regulation of neural precursor cell proliferation 11 2.532303
GO:0032098 regulation of appetite 11 2.530478
GO:0021602 cranial nerve morphogenesis 12 2.739915
GO:0043092 L-amino acid import 8 2.710575
GO:0035024 negative regulation of Rho protein signal transduction 8 2.695921
GO:0001667 ameboidal cell migration 50 2.642144
GO:0003197 endocardial cushion development 9 2.513881
GO:0061384 heart trabecular morphogenesis 8 2.602449
GO:0050673 epithelial cell proliferation 34 2.5166
GO:0009799 specification of symmetry 68 2.431327
GO:0010665 regulation of cardiac muscle cell apoptosis 7 2.659828
GO:0051057 positive regulation of small GTPase mediated signal transduction 26 2.708585
GO:0030501 positive regulation of bone mineralization 26 2.682341
GO:0021532 neural tube patterning 26 2.680535
GO:0000578 embryonic axis specification 26 2.671812
GO:0021830 interneuron migration from the subpallium to the cortex 5 2.746613
GO:0021853 cerebral cortex GABAergic interneuron migration 5 2.746613
GO:0021894 cerebral cortex GABAergic interneuron development 5 2.746613
GO:0030854 positive regulation of granulocyte differentiation 5 2.735155
GO:0043951 negative regulation of cAMP-mediated signaling 5 2.730216
GO:0007386 compartment pattern formation 5 2.709614
GO:0071396 cellular response to lipid 21 2.375067
GO:0045725 positive regulation of glycogen biosynthetic process 13 2.509276
GO:0018394 peptidyl-lysine acetylation 78 2.57363
GO:0009713 catechol biosynthetic process 15 2.87307
GO:0034312 diol biosynthetic process 15 2.87307
GO:0042423 catecholamine biosynthetic process 15 2.87307
GO:0046856 phosphatidylinositol dephosphorylation 7 2.6481
GO:0060136 embryonic process involved in female pregnancy 7 2.638471
GO:0015682 ferric iron transport 30 2.59783
GO:0033572 transferrin transport 30 2.59783
GO:0042136 neurotransmitter biosynthetic process 14 2.554755
GO:0070875 positive regulation of glycogen metabolic process 14 2.48585
GO:0006835 dicarboxylic acid transport 14 2.445204
GO:0048557 embryonic digestive tract morphogenesis 15 2.773941
GO:0031058 positive regulation of histone modification 27 2.613084
GO:0032101 regulation of response to external stimulus 264 2.602633
GO:0051084 'de novo' posttranslational protein folding 48 2.765548
GO:0071277 cellular response to calcium ion 15 2.668032
GO:0015813 L-glutamate transport 15 2.588885
GO:0043567 regulation of insulin-like growth factor receptor signaling pathway 15 2.568875
GO:0032846 positive regulation of homeostatic process 60 2.407433
GO:0010595 positive regulation of endothelial cell migration 33 2.538455
GO:0051954 positive regulation of amine transport 17 2.580387
GO:0006164 purine nucleotide biosynthetic process 138 2.580989
GO:0001706 endoderm formation 14 2.304545
GO:0051647 nucleus localization 14 2.269305
GO:0045838 positive regulation of membrane potential 6 2.690181
GO:0014896 muscle hypertrophy 6 2.652575
GO:0072205 metanephric collecting duct development 6 2.632771
GO:0003337 mesenchymal to epithelial transition involved in metanephros morphogenesis 6 2.617229
GO:0006939 smooth muscle contraction 32 2.494175
GO:0007606 sensory perception of chemical stimulus 117 2.36424
GO:0010921 regulation of phosphatase activity 27 2.578622
GO:0071634 regulation of transforming growth factor-beta production 16 2.551092
GO:0030279 negative regulation of ossification 16 2.542696
GO:0019079 viral genome replication 16 2.523601
GO:0003401 axis elongation 16 2.473011
GO:0031623 receptor internalization 23 2.570446
GO:0010907 positive regulation of glucose metabolic process 23 2.557946
GO:0048286 lung alveolus development 34 2.360223
GO:0050982 detection of mechanical stimulus 12 2.729727
GO:0006403 RNA localization 129 2.394764
GO:0006897 endocytosis 240 2.281528
GO:0010324 membrane invagination 240 2.281528
GO:0048025 negative regulation of nuclear mRNA splicing, via spliceosome 8 2.563965
GO:0060638 mesenchymal-epithelial cell signaling 9 2.500242
GO:0035094 response to nicotine 33 2.371178
GO:0048146 positive regulation of fibroblast proliferation 33 2.338043
GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation 18 2.489335
GO:0034394 protein localization at cell surface 18 2.473414
GO:0030432 peristalsis 8 2.558963
GO:0001993 regulation of systemic arterial blood pressure by norepinephrine-epinephrine 8 2.549361
GO:0032922 circadian regulation of gene expression 8 2.47356
GO:0043129 surfactant homeostasis 8 2.46849
GO:0048875 chemical homeostasis within a tissue 8 2.46849
GO:0021884 forebrain neuron development 8 2.464417
GO:0048266 behavioral response to pain 8 2.444077
GO:0031060 regulation of histone methylation 12 2.699963
GO:0009123 nucleoside monophosphate metabolic process 84 2.349723
GO:0048015 phosphatidylinositol-mediated signaling 84 2.255049
GO:0048017 inositol lipid-mediated signaling 84 2.255049
GO:0002576 platelet degranulation 82 2.510842
GO:0048661 positive regulation of smooth muscle cell proliferation 35 2.356301
GO:0070997 neuron death 20 2.72642
GO:0040036 regulation of fibroblast growth factor receptor signaling pathway 20 2.632572
GO:0072028 nephron morphogenesis 20 2.565357
GO:0048643 positive regulation of skeletal muscle tissue development 8 2.420895
GO:0045663 positive regulation of myoblast differentiation 8 2.358436
GO:0042044 fluid transport 38 2.295862
GO:0090183 regulation of kidney development 44 2.443851
GO:0006406 mRNA export from nucleus 60 2.289729
GO:0043666 regulation of phosphoprotein phosphatase activity 21 2.15868
GO:0048645 organ formation 21 2.153046
GO:0045648 positive regulation of erythrocyte differentiation 15 2.550009
GO:0048660 regulation of smooth muscle cell proliferation 59 2.497902
GO:0006475 internal protein amino acid acetylation 78 2.282052
GO:0003081 regulation of systemic arterial blood pressure by renin-angiotensin 14 2.208509
GO:0009791 post-embryonic development 75 2.47169
GO:0006405 RNA export from nucleus 67 2.415406
GO:0009855 determination of bilateral symmetry 67 2.396162
GO:0072170 metanephric tubule development 11 2.388953
GO:0030878 thyroid gland development 16 2.399806
GO:0061383 trabecula morphogenesis 16 2.38942
GO:0090003 regulation of establishment of protein localization in plasma membrane 17 2.483375
GO:0046627 negative regulation of insulin receptor signaling pathway 17 2.478784
GO:0072215 regulation of metanephros development 17 2.471238
GO:0048745 smooth muscle tissue development 17 2.447249
GO:0060444 branching involved in mammary gland duct morphogenesis 17 2.43537
GO:0045786 negative regulation of cell cycle 217 2.248481
GO:0001954 positive regulation of cell-matrix adhesion 17 2.388004
GO:0051302 regulation of cell division 61 2.271233
GO:0031102 neuron projection regeneration 20 2.534796
GO:0001889 liver development 73 2.677477
GO:0002755 MyD88-dependent toll-like receptor signaling pathway 73 2.664366
GO:0045980 negative regulation of nucleotide metabolic process 12 2.558496
GO:0042069 regulation of catecholamine metabolic process 12 2.550787
GO:0007017 microtubule-based process 285 2.252046
GO:0010638 positive regulation of organelle organization 152 2.313777
GO:0007620 copulation 17 2.358964
GO:0051482 elevation of cytosolic calcium ion concentration involved in G-protein signaling coupled to IP3 second messenger 12 2.521937
GO:0021873 forebrain neuroblast division 8 2.3141
GO:0055057 neuroblast division 8 2.3141
GO:0007183 SMAD protein complex assembly 8 2.313965
GO:0021683 cerebellar granular layer morphogenesis 7 2.595222
GO:0014902 myotube differentiation 19 2.618905
GO:0048070 regulation of developmental pigmentation 9 2.479999
GO:0050795 regulation of behavior 102 2.102891
GO:0061098 positive regulation of protein tyrosine kinase activity 22 2.354626
GO:0051489 regulation of filopodium assembly 16 2.361311
GO:0035088 establishment or maintenance of apical/basal cell polarity 16 2.312028
GO:0061245 establishment or maintenance of bipolar cell polarity 16 2.312028
GO:0055012 ventricular cardiac muscle cell differentiation 16 2.260728
GO:0045844 positive regulation of striated muscle tissue development 12 2.502547
GO:0048636 positive regulation of muscle organ development 12 2.502547
GO:0006301 postreplication repair 12 2.409818
GO:0072207 metanephric epithelium development 12 2.38683
GO:0008105 asymmetric protein localization 12 2.368911
GO:0050880 regulation of blood vessel size 49 2.506797
GO:0046426 negative regulation of JAK-STAT cascade 9 2.43431
GO:0072077 renal vesicle morphogenesis 9 2.41097
GO:0007224 smoothened signaling pathway 33 2.275034
GO:0048730 epidermis morphogenesis 33 2.270369
GO:0071453 cellular response to oxygen levels 35 2.253629
GO:0007254 JNK cascade 77 2.578375
GO:0032099 negative regulation of appetite 6 2.558055
GO:0015810 aspartate transport 6 2.549868
GO:0060052 neurofilament cytoskeleton organization 6 2.548476
GO:0060445 branching involved in salivary gland morphogenesis 15 2.339592
GO:0021978 telencephalon regionalization 5 2.652969
GO:0030947 regulation of vascular endothelial growth factor receptor signaling pathway 20 2.484867
GO:0051402 neuron apoptosis 15 2.289693
GO:0008624 induction of apoptosis by extracellular signals 119 2.373674
GO:0048534 hemopoietic or lymphoid organ development 296 2.343849
GO:0031670 cellular response to nutrient 58 2.283134
GO:0035176 social behavior 22 2.317131
GO:0042311 vasodilation 22 2.294857
GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback 6 2.51317
GO:0010667 negative regulation of cardiac muscle cell apoptosis 6 2.510438
GO:0021797 forebrain anterior/posterior pattern formation 6 2.502513
GO:0051938 L-glutamate import 6 2.497655
GO:0043470 regulation of carbohydrate catabolic process 23 2.379978
GO:0043471 regulation of cellular carbohydrate catabolic process 23 2.379978
GO:0051281 positive regulation of release of sequestered calcium ion into cytosol 13 2.355677
GO:0030431 sleep 13 2.335491
GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport 143 1.832531
GO:0031998 regulation of fatty acid beta-oxidation 11 2.266364
GO:0034104 negative regulation of tissue remodeling 11 2.186305
GO:0060602 branch elongation of an epithelium 11 2.155938
GO:0007595 lactation 31 2.224685
GO:0006607 NLS-bearing substrate import into nucleus 13 2.30722
GO:0051893 regulation of focal adhesion assembly 13 2.297003
GO:0090109 regulation of cell-substrate junction assembly 13 2.297003
GO:0045921 positive regulation of exocytosis 20 2.368141
GO:0060428 lung epithelium development 20 2.362714
GO:0007090 regulation of S phase of mitotic cell cycle 20 2.300917
GO:0060389 pathway-restricted SMAD protein phosphorylation 12 2.258956
GO:0007320 insemination 12 2.241698
GO:0009142 nucleoside triphosphate biosynthetic process 86 2.119269
GO:0048259 regulation of receptor-mediated endocytosis 31 2.126277
GO:0051341 regulation of oxidoreductase activity 60 2.180855
GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway 9 2.245649
GO:0051927 negative regulation of calcium ion transport via voltage-gated calcium channel activity 9 2.233435
GO:0002063 chondrocyte development 9 2.224427
GO:0006817 phosphate transport 8 2.207083
GO:0043367 CD4-positive, alpha-beta T cell differentiation 8 2.191308
GO:0001755 neural crest cell migration 29 2.231185
GO:0019047 provirus integration 8 2.161001
GO:0030069 lysogeny 8 2.161001
GO:0009584 detection of visible light 20 2.201591
GO:0060253 negative regulation of glial cell proliferation 6 2.445155
GO:0072088 nephron epithelium morphogenesis 19 2.383885
GO:0001570 vasculogenesis 51 2.19737
GO:0051901 positive regulation of mitochondrial depolarization 5 2.53428
GO:0001938 positive regulation of endothelial cell proliferation 40 2.304992
GO:0035150 regulation of tube size 50 2.455223
GO:0006596 polyamine biosynthetic process 11 2.154021
GO:0030539 male genitalia development 21 2.040908
GO:0030035 microspike assembly 27 2.256305
GO:0051291 protein heterooligomerization 50 2.330006
GO:2000677 regulation of transcription regulatory region DNA binding 8 2.123499
GO:0021681 cerebellar granular layer development 8 2.112109
GO:0048145 regulation of fibroblast proliferation 47 2.266509
GO:0019229 regulation of vasoconstriction 47 2.252844
GO:0007286 spermatid development 67 2.160119
GO:0021511 spinal cord patterning 16 2.211016
GO:0033138 positive regulation of peptidyl-serine phosphorylation 31 2.039822
GO:0043967 histone H4 acetylation 31 1.965973
GO:0015988 energy coupled proton transport, against electrochemical gradient 31 1.947483
GO:0015991 ATP hydrolysis coupled proton transport 31 1.947483
GO:0051017 actin filament bundle assembly 25 2.321766
GO:0002762 negative regulation of myeloid leukocyte differentiation 25 2.315697
GO:0070170 regulation of tooth mineralization 7 2.537371
GO:0001574 ganglioside biosynthetic process 7 2.530634
GO:0048148 behavioral response to cocaine 7 2.530193
GO:0030917 midbrain-hindbrain boundary development 10 2.418454
GO:0012502 induction of programmed cell death 350 2.02051
GO:0060343 trabecula formation 15 2.176855
GO:0072009 nephron epithelium development 24 2.537165
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway 34 2.092045
GO:0070271 protein complex biogenesis 492 2.090206
GO:0007281 germ cell development 116 2.311392
GO:0030835 negative regulation of actin filament depolymerization 25 2.253681
GO:0032414 positive regulation of ion transmembrane transporter activity 22 2.169685
GO:0007163 establishment or maintenance of cell polarity 73 2.489442
GO:0006970 response to osmotic stress 41 2.032145
GO:0001658 branching involved in ureteric bud morphogenesis 41 2.011181
GO:0003014 renal system process 41 1.990045
GO:0010811 positive regulation of cell-substrate adhesion 44 2.36458
GO:0070741 response to interleukin-6 13 2.169796
GO:0030856 regulation of epithelial cell differentiation 42 2.051792
GO:0009145 purine nucleoside triphosphate biosynthetic process 84 2.171263
GO:0009201 ribonucleoside triphosphate biosynthetic process 84 2.170955
GO:0033135 regulation of peptidyl-serine phosphorylation 38 1.935351
GO:0007015 actin filament organization 90 2.344847
GO:0051894 positive regulation of focal adhesion assembly 7 2.512223
GO:0045836 positive regulation of meiosis 7 2.506991
GO:0050685 positive regulation of mRNA processing 7 2.504319
GO:0072283 metanephric renal vesicle morphogenesis 7 2.489853
GO:0080135 regulation of cellular response to stress 181 2.282445
GO:0032352 positive regulation of hormone metabolic process 12 2.180171
GO:0060896 neural plate pattern specification 9 2.15605
GO:0045670 regulation of osteoclast differentiation 33 2.027055
GO:0071900 regulation of protein serine/threonine kinase activity 303 2.222075
GO:0022601 menstrual cycle phase 7 2.476251
GO:0048515 spermatid differentiation 70 2.144407
GO:0030855 epithelial cell differentiation 200 2.195126
GO:0018393 internal peptidyl-lysine acetylation 77 2.40164
GO:0008063 Toll signaling pathway 77 2.375655
GO:0001541 ovarian follicle development 49 2.073315
GO:0042755 eating behavior 26 2.349468
GO:0001823 mesonephros development 19 2.25663
GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway 26 2.251493
GO:0030073 insulin secretion 26 2.241678
GO:0010524 positive regulation of calcium ion transport into cytosol 25 2.171204
GO:0050912 detection of chemical stimulus involved in sensory perception of taste 21 1.952208
GO:0001893 maternal placenta development 21 1.931386
GO:0048066 developmental pigmentation 33 2.000044
GO:0051412 response to corticosterone stimulus 23 2.244546
GO:0045104 intermediate filament cytoskeleton organization 23 2.179153
GO:0090090 negative regulation of canonical Wnt receptor signaling pathway 57 2.234543
GO:0045292 nuclear mRNA cis splicing, via spliceosome 6 2.417739
GO:0060986 endocrine hormone secretion 6 2.364071
GO:0055075 potassium ion homeostasis 6 2.358306
GO:0060023 soft palate development 6 2.347337
GO:0021684 cerebellar granular layer formation 6 2.339057
GO:0021707 cerebellar granule cell differentiation 6 2.339057
GO:0043497 regulation of protein heterodimerization activity 6 2.327586
GO:0021548 pons development 6 2.311653
GO:0045924 regulation of female receptivity 6 2.304739
GO:0060180 female mating behavior 6 2.304739
GO:0060592 mammary gland formation 6 2.239198
GO:0032317 regulation of Rap GTPase activity 6 2.190475
GO:0032487 regulation of Rap protein signal transduction 6 2.190475
GO:0042940 D-amino acid transport 5 2.465933
GO:0045578 negative regulation of B cell differentiation 5 2.46131
GO:0007195 inhibition of adenylate cyclase activity by dopamine receptor signaling pathway 5 2.389513
GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan 5 2.373457
GO:0002042 cell migration involved in sprouting angiogenesis 5 2.364423
GO:0046850 regulation of bone remodeling 22 2.144558
GO:0048844 artery morphogenesis 20 2.078724
GO:0046579 positive regulation of Ras protein signal transduction 24 2.161995
GO:0042737 drug catabolic process 11 2.145002
GO:0033119 negative regulation of RNA splicing 11 2.073743
GO:0055067 monovalent inorganic cation homeostasis 44 2.231709
GO:0009629 response to gravity 13 2.107427
GO:0007567 parturition 13 2.104309
GO:0046825 regulation of protein export from nucleus 13 2.100539
GO:0052312 modulation of transcription in other organism involved in symbiotic interaction 13 2.099141
GO:0061005 cell differentiation involved in kidney development 13 2.050164
GO:0055007 cardiac muscle cell differentiation 40 2.245681
GO:0009886 post-embryonic morphogenesis 8 2.041356
GO:0071560 cellular response to transforming growth factor beta stimulus 18 2.258934
GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway 18 2.245566
GO:0035336 long-chain fatty-acyl-CoA metabolic process 18 2.228415
GO:0035338 long-chain fatty-acyl-CoA biosynthetic process 18 2.228415
GO:0060415 muscle tissue morphogenesis 39 2.149291
GO:0051693 actin filament capping 23 2.100543
GO:0045668 negative regulation of osteoblast differentiation 25 2.081098
GO:0060510 Type II pneumocyte differentiation 5 2.327055
GO:0007368 determination of left/right symmetry 64 2.149187
GO:0060685 regulation of prostatic bud formation 6 2.121322
GO:0061178 regulation of insulin secretion involved in cellular response to glucose stimulus 6 2.112891
GO:0007501 mesodermal cell fate specification 5 2.299028
GO:0050657 nucleic acid transport 124 2.111787
GO:0050658 RNA transport 124 2.111787
GO:0051236 establishment of RNA localization 124 2.111787
GO:0009206 purine ribonucleoside triphosphate biosynthetic process 83 2.285326
GO:0016573 histone acetylation 75 2.07459
GO:0009750 response to fructose stimulus 8 2.008945
GO:0042753 positive regulation of circadian rhythm 8 1.996975
GO:0001967 suckling behavior 8 1.98987
GO:0045176 apical protein localization 9 2.065333
GO:0010677 negative regulation of cellular carbohydrate metabolic process 14 1.95534
GO:0045912 negative regulation of carbohydrate metabolic process 14 1.95534
GO:0071695 anatomical structure maturation 26 2.180798
GO:0048678 response to axon injury 39 1.903756
GO:0060675 ureteric bud morphogenesis 46 2.092777
GO:0051928 positive regulation of calcium ion transport 55 2.031591
GO:0033604 negative regulation of catecholamine secretion 8 1.967258
GO:0030500 regulation of bone mineralization 44 2.11953
GO:0035115 embryonic forelimb morphogenesis 26 2.129439
GO:0006461 protein complex assembly 489 2.135533
GO:0035567 non-canonical Wnt receptor signaling pathway 24 2.10517
GO:0050821 protein stabilization 47 2.115838
GO:0031123 RNA 3'-end processing 83 2.172033
GO:2000243 positive regulation of reproductive process 83 2.087225
GO:0000086 G2/M transition of mitotic cell cycle 116 1.963658
GO:0071456 cellular response to hypoxia 32 2.080126
GO:0051492 regulation of stress fiber assembly 25 2.009853
GO:0022408 negative regulation of cell-cell adhesion 16 2.141408
GO:0000910 cytokinesis 62 2.064493
GO:0010171 body morphogenesis 27 2.167499
GO:0072522 purine-containing compound biosynthetic process 150 2.129717
GO:0010453 regulation of cell fate commitment 22 1.934908
GO:0048703 embryonic viscerocranium morphogenesis 9 2.044979
GO:0072176 nephric duct development 9 2.006138
GO:0048714 positive regulation of oligodendrocyte differentiation 9 2.001674
GO:0002686 negative regulation of leukocyte migration 9 1.990277
GO:0060998 regulation of dendritic spine development 9 1.957617
GO:0046851 negative regulation of bone remodeling 9 1.951683
GO:0031935 regulation of chromatin silencing 9 1.947518
GO:0010922 positive regulation of phosphatase activity 9 1.924836
GO:0001825 blastocyst formation 23 2.04754
GO:0021680 cerebellar Purkinje cell layer development 14 1.937233
GO:0001502 cartilage condensation 14 1.926143
GO:0048384 retinoic acid receptor signaling pathway 15 2.081473
GO:0032225 regulation of synaptic transmission, dopaminergic 15 2.079396
GO:0032770 positive regulation of monooxygenase activity 15 2.057819
GO:0016486 peptide hormone processing 25 1.920622
GO:0002028 regulation of sodium ion transport 24 2.095397
GO:0001947 heart looping 35 1.903511
GO:0003143 embryonic heart tube morphogenesis 35 1.903511
GO:0061371 determination of heart left/right asymmetry 35 1.903511
GO:0018205 peptidyl-lysine modification 99 1.83683
GO:0045737 positive regulation of cyclin-dependent protein kinase activity 13 1.952822
GO:0060351 cartilage development involved in endochondral bone morphogenesis 13 1.879563
GO:0072078 nephron tubule morphogenesis 13 1.864926
GO:0060693 regulation of branching involved in salivary gland morphogenesis 8 1.93452
GO:0007217 tachykinin receptor signaling pathway 8 1.913354
GO:0072178 nephric duct morphogenesis 8 1.912968
GO:0006936 muscle contraction 176 2.11753
GO:0006664 glycolipid metabolic process 37 1.998603
GO:0033145 positive regulation of steroid hormone receptor signaling pathway 6 2.088813
GO:0044344 cellular response to fibroblast growth factor stimulus 6 2.084298
GO:0071774 response to fibroblast growth factor stimulus 6 2.084298
GO:0008207 C21-steroid hormone metabolic process 28 1.962299
GO:0060840 artery development 22 1.766436
GO:0045930 negative regulation of mitotic cell cycle 22 1.759589
GO:0032232 negative regulation of actin filament bundle assembly 6 2.054301
GO:0003148 outflow tract septum morphogenesis 6 2.051672
GO:0008089 anterograde axon cargo transport 6 2.048773
GO:0014060 regulation of epinephrine secretion 6 2.048549
GO:0021554 optic nerve development 6 2.020733
GO:0031657 regulation of cyclin-dependent protein kinase activity involved by G1/S 6 2.01823
GO:0032319 regulation of Rho GTPase activity 69 2.118677
GO:0010770 positive regulation of cell morphogenesis involved in differentiation 24 2.042975
GO:0071636 positive regulation of transforming growth factor-beta production 9 1.920827
GO:0046503 glycerolipid catabolic process 24 1.992114
GO:0001666 response to hypoxia 203 1.908888
GO:0032886 regulation of microtubule-based process 67 1.938539
GO:0006898 receptor-mediated endocytosis 67 1.845329
GO:0006917 induction of apoptosis 348 1.844454
GO:0060795 cell fate commitment involved in formation of primary germ layers 20 1.999699
GO:0019319 hexose biosynthetic process 50 1.970997
GO:0032874 positive regulation of stress-activated MAPK cascade 14 1.82849
GO:0043536 positive regulation of blood vessel endothelial cell migration 19 1.993224
GO:0061326 renal tubule development 19 1.992447
GO:0033146 regulation of estrogen receptor signaling pathway 9 1.894724
GO:0071392 cellular response to estradiol stimulus 8 1.827927
GO:0048484 enteric nervous system development 18 2.093159
GO:0042347 negative regulation of NF-kappaB import into nucleus 11 1.847933
GO:0043584 nose development 11 1.84492
GO:0060742 epithelial cell differentiation involved in prostate gland development 11 1.833799
GO:0051168 nuclear export 84 1.80401
GO:0031099 regeneration 106 1.870886
GO:0072080 nephron tubule development 18 2.065339
GO:0042745 circadian sleep/wake cycle 18 2.045801
GO:0061333 renal tubule morphogenesis 14 1.776344
GO:0055081 anion homeostasis 14 1.771646
GO:0007494 midgut development 14 1.762009
GO:0032321 positive regulation of Rho GTPase activity 55 1.995958
GO:0009649 entrainment of circadian clock 8 1.798021
GO:0042634 regulation of hair cycle 8 1.780487
GO:0046834 lipid phosphorylation 17 2.186499
GO:0021846 cell proliferation in forebrain 17 2.102602
GO:0002763 positive regulation of myeloid leukocyte differentiation 27 2.097819
GO:0046822 regulation of nucleocytoplasmic transport 115 2.087805
GO:0045884 regulation of survival gene product expression 21 1.895948
GO:0060765 regulation of androgen receptor signaling pathway 16 2.005142
GO:0006972 hyperosmotic response 16 2.00509
GO:0006110 regulation of glycolysis 16 1.942016
GO:0006182 cGMP biosynthetic process 15 1.941347
GO:0007271 synaptic transmission, cholinergic 19 1.873909
GO:0032096 negative regulation of response to food 7 2.430653
GO:0016081 synaptic vesicle docking involved in exocytosis 7 2.374511
GO:0072044 collecting duct development 7 2.366972
GO:0060347 heart trabecula formation 7 2.356262
GO:0048664 neuron fate determination 7 2.354825
GO:0060601 lateral sprouting from an epithelium 7 2.3524
GO:0008343 adult feeding behavior 7 2.35108
GO:0010092 specification of organ identity 7 2.339534
GO:2000018 regulation of male gonad development 7 2.284737
GO:0060206 estrous cycle phase 7 2.269156
GO:0060259 regulation of feeding behavior 7 2.218481
GO:0031915 positive regulation of synaptic plasticity 7 2.212357
GO:0060124 positive regulation of growth hormone secretion 7 2.191594
GO:0045116 protein neddylation 7 2.159785
GO:0006491 N-glycan processing 7 2.155465
GO:0043149 stress fiber assembly 7 2.131187
GO:0046165 alcohol biosynthetic process 87 1.853589
GO:0001990 regulation of systemic arterial blood pressure by hormone 21 1.813348
GO:0010739 positive regulation of protein kinase A signaling cascade 5 2.295448
GO:0044341 sodium-dependent phosphate transport 5 2.28498
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling 5 2.241812
GO:0043084 penile erection 5 2.232211
GO:0010919 regulation of inositol phosphate biosynthetic process 5 2.209081
GO:0050951 sensory perception of temperature stimulus 5 2.198621
GO:0007343 egg activation 5 2.154439
GO:0035305 negative regulation of dephosphorylation 5 2.112126
GO:0035308 negative regulation of protein dephosphorylation 5 2.112126
GO:0061088 regulation of sequestering of zinc ion 5 2.090819
GO:0050910 detection of mechanical stimulus involved in sensory perception of sound 5 2.088878
GO:0043502 regulation of muscle adaptation 19 1.847283
GO:0010608 posttranscriptional regulation of gene expression 283 1.725887
GO:0007097 nuclear migration 6 1.994145
GO:0001821 histamine secretion 6 1.957169
GO:0002520 immune system development 324 1.717872
GO:0008298 intracellular mRNA localization 5 2.053982
GO:0046364 monosaccharide biosynthetic process 62 1.791594
GO:0048260 positive regulation of receptor-mediated endocytosis 21 1.793563
GO:0060135 maternal process involved in female pregnancy 21 1.776932
GO:0016575 histone deacetylation 21 1.775138
GO:0030041 actin filament polymerization 12 2.101848
GO:0048339 paraxial mesoderm development 12 2.100585
GO:0000060 protein import into nucleus, translocation 18 2.023585
GO:0030852 regulation of granulocyte differentiation 11 1.773404
GO:0045885 positive regulation of survival gene product expression 11 1.763935
GO:0018198 peptidyl-cysteine modification 11 1.725067
GO:0048588 developmental cell growth 30 2.097204
GO:0032231 regulation of actin filament bundle assembly 30 2.092976
GO:0050690 regulation of defense response to virus by virus 28 1.940045
GO:0016574 histone ubiquitination 28 1.926633
GO:0071902 positive regulation of protein serine/threonine kinase activity 176 1.983607
GO:0046847 filopodium assembly 26 1.843198
GO:0031532 actin cytoskeleton reorganization 26 1.833542
GO:0030834 regulation of actin filament depolymerization 29 1.684275
GO:0001933 negative regulation of protein phosphorylation 56 1.999321
GO:0046365 monosaccharide catabolic process 77 1.813064
GO:0050907 detection of chemical stimulus involved in sensory perception 61 1.801693
GO:0019695 choline metabolic process 5 1.976925
GO:0051282 regulation of sequestering of calcium ion 20 1.882024
GO:0006338 chromatin remodeling 89 1.983237
GO:0032924 activin receptor signaling pathway 6 1.9366
GO:0001554 luteolysis 6 1.923884
GO:0060684 epithelial-mesenchymal cell signaling 6 1.920738
GO:0002224 toll-like receptor signaling pathway 87 1.804901
GO:0007160 cell-matrix adhesion 87 1.721632
GO:0050810 regulation of steroid biosynthetic process 41 1.471276
GO:0072087 renal vesicle development 10 2.352252
GO:0043543 protein acylation 97 2.012022
GO:0060325 face morphogenesis 19 1.787942
GO:0010460 positive regulation of heart rate 14 1.747463
GO:0031103 axon regeneration 14 1.723428
GO:0050732 negative regulation of peptidyl-tyrosine phosphorylation 14 1.721725
GO:0051593 response to folic acid 9 1.865063
GO:0001101 response to acid 64 1.890604
GO:0022410 circadian sleep/wake cycle process 17 2.069485
GO:0035304 regulation of protein dephosphorylation 13 1.817803
GO:0045671 negative regulation of osteoclast differentiation 13 1.734079
GO:0043491 protein kinase B signaling cascade 13 1.728363
GO:0046689 response to mercury ion 13 1.711735
GO:0060438 trachea development 13 1.695715
GO:0048846 axon extension involved in axon guidance 13 1.692287
GO:0042659 regulation of cell fate specification 14 1.677638
GO:0048635 negative regulation of muscle organ development 14 1.621152
GO:0046328 regulation of JNK cascade 104 1.842962
GO:0042246 tissue regeneration 37 1.826438
GO:0031668 cellular response to extracellular stimulus 141 1.939818
GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity 133 1.889736
GO:0090047 positive regulation of transcription regulator activity 133 1.889736
GO:0006473 protein acetylation 85 1.935687
GO:0045124 regulation of bone resorption 21 1.665217
GO:0031334 positive regulation of protein complex assembly 72 1.746617
GO:0050995 negative regulation of lipid catabolic process 14 1.595527
GO:0045471 response to ethanol 98 1.879812
GO:0050909 sensory perception of taste 48 1.828689
GO:0061029 eyelid development in camera-type eye 8 1.763055
GO:0031958 corticosteroid receptor signaling pathway 8 1.745024
GO:0042921 glucocorticoid receptor signaling pathway 8 1.745024
GO:0010470 regulation of gastrulation 17 2.004098
GO:0015844 monoamine transport 17 2.001357
GO:0048675 axon extension 22 1.703563
GO:0046209 nitric oxide metabolic process 23 1.870703
GO:0045646 regulation of erythrocyte differentiation 23 1.869583
GO:0070302 regulation of stress-activated protein kinase signaling cascade 113 1.997046
GO:0030851 granulocyte differentiation 9 1.785553
GO:0003321 positive regulation of blood pressure by epinephrine-norepinephrine 7 2.122523
GO:0043473 pigmentation 70 1.747247
GO:0007338 single fertilization 70 1.654251
GO:0060323 head morphogenesis 21 1.617232
GO:0071108 protein K48-linked deubiquitination 10 2.234548
GO:0007512 adult heart development 13 1.618417
GO:0003084 positive regulation of systemic arterial blood pressure 13 1.604673
GO:0007091 mitotic metaphase/anaphase transition 13 1.589238
GO:0000768 syncytium formation by plasma membrane fusion 10 2.204455
GO:0007520 myoblast fusion 10 2.204455
GO:0090030 regulation of steroid hormone biosynthetic process 10 2.18943
GO:0002011 morphogenesis of an epithelial sheet 10 2.174339
GO:0007625 grooming behavior 10 2.100614
GO:0060317 cardiac epithelial to mesenchymal transition 10 2.094875
GO:0030097 hemopoiesis 263 1.855455
GO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway 12 2.004782
GO:0050775 positive regulation of dendrite morphogenesis 12 1.983043
GO:0045103 intermediate filament-based process 24 1.947926
GO:0006586 indolalkylamine metabolic process 24 1.82037
GO:0042430 indole-containing compound metabolic process 24 1.82037
GO:0030317 sperm motility 24 1.812312
GO:0007622 rhythmic behavior 22 1.635784
GO:0021520 spinal cord motor neuron cell fate specification 7 2.098754
GO:0003309 type B pancreatic cell differentiation 7 2.097656
GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity 7 2.061973
GO:0006590 thyroid hormone generation 7 1.981381
GO:0042670 retinal cone cell differentiation 7 1.937172
GO:0046549 retinal cone cell development 7 1.937172
GO:0032891 negative regulation of organic acid transport 7 1.926022
GO:0031936 negative regulation of chromatin silencing 7 1.915816
GO:0046823 negative regulation of nucleocytoplasmic transport 38 1.757946
GO:0022407 regulation of cell-cell adhesion 44 1.915175
GO:0006000 fructose metabolic process 17 1.78901
GO:0051148 negative regulation of muscle cell differentiation 19 1.73071
GO:0051145 smooth muscle cell differentiation 19 1.70969
GO:0071391 cellular response to estrogen stimulus 12 1.940426
GO:0072079 nephron tubule formation 12 1.81333
GO:0001573 ganglioside metabolic process 12 1.791276
GO:0071599 otic vesicle development 12 1.72314
GO:0043388 positive regulation of DNA binding 18 1.852859
GO:0016322 neuron remodeling 6 1.769388
GO:0033504 floor plate development 6 1.763457
GO:0006538 glutamate catabolic process 6 1.745994
GO:0031960 response to corticosteroid stimulus 138 1.601559
GO:0051028 mRNA transport 111 1.929321
GO:0051495 positive regulation of cytoskeleton organization 75 1.532516
GO:0033261 regulation of S phase 28 1.821276
GO:0002029 desensitization of G-protein coupled receptor protein signaling pathway 14 1.506437
GO:0022401 negative adaptation of signaling pathway 14 1.506437
GO:0023058 adaptation of signaling pathway 14 1.506437
GO:0006929 substrate-dependent cell migration 14 1.49452
ID ?Description ?Number of genes ?Score ?
CBC.04 Cerebellar cortex | Early midfetal 1 1920 17.869989
MD.05 Mediodorsal nucleus of thalamus | Early midfetal 2 2064 16.311273
STR.05 Striatum | Early midfetal 2 1525 15.30045
CBC.03 Cerebellar cortex | Early fetal 2 2953 13.531872
OFC.05 Orbital prefrontal cortex | Early midfetal 2 1152 12.8711
STC.06 Superior temporal cortex | Late midfetal 1143 12.746011
AMY.11 Amygdala | Middle late childhood 642 12.592518
MD.04 Mediodorsal nucleus of thalamus | Early midfetal 1 3660 12.372169
HIP.11 Hippocampus | Middle late childhood 923 12.183144
MFC.06 Medial prefrontal cortex | Late midfetal 660 11.641828
M1C.06 Primary motor cortex | Late midfetal 740 11.477326
STR.03 Striatum | Early fetal 2 1697 10.850214
STC.03 Superior temporal cortex | Early fetal 2 789 10.346072
ITC.06 Inferior temporal cortex | Late midfetal 620 10.07366
ITC.05 Inferior temporal cortex | Early midfetal 2 928 8.815787
S1C.06 Primary somatosensory cortex | Late midfetal 826 8.561292
MD.03 Mediodorsal nucleus of thalamus | Early fetal 2 3740 8.49074
MD.09 Mediodorsal nucleus of thalamus | Late infancy 1497 8.388304
IPC.04 Posterior inferior parietal cortex | Early midfetal 1 1659 8.380021
M1C.03 Primary motor cortex | Early fetal 2 1193 8.29445
MD.06 Mediodorsal nucleus of thalamus | Late midfetal 2098 8.134268
VFC.06 Ventrolateral prefrontal cortex | Late midfetal 672 7.791311
IPC.06 Posterior inferior parietal cortex | Late midfetal 763 7.694289
STR.04 Striatum | Early midfetal 1 1735 7.497568
A1C.04 Primary auditory cortex | Early midfetal 1 677 7.286861
A1C.03 Primary auditory cortex | Early fetal 2 961 7.102533
A1C.07 Primary auditory cortex | Late fetal 778 7.015167
VFC.09 Ventrolateral prefrontal cortex | Late infancy 221 6.966864
STC.07 Superior temporal cortex | Late fetal 529 6.484691
IPC.12 Posterior inferior parietal cortex | Adolescence 124 6.352367
A1C.06 Primary auditory cortex | Late midfetal 796 6.221089
STR.12 Striatum | Adolescence 1555 6.204438
HIP.06 Hippocampus | Late midfetal 1312 6.007238
ITC.07 Inferior temporal cortex | Late fetal 566 5.934069
OFC.06 Orbital prefrontal cortex | Late midfetal 1106 5.870934
AMY.02 Amygdala | Early fetal 1 1604 5.584559
VFC.05 Ventrolateral prefrontal cortex | Early midfetal 2 1288 5.459512
M1C.04 Primary motor cortex | Early midfetal 1 1454 5.382768
HIP.08 Hippocampus | Neonatal early infancy 670 5.24436
VFC.04 Ventrolateral prefrontal cortex | Early midfetal 1 1585 5.14132
ITC.08 Inferior temporal cortex | Neonatal early infancy 560 5.127529
S1C.04 Primary somatosensory cortex | Early midfetal 1 888 5.004029
DFC.12 Dorsolateral prefrontal cortex | Adolescence 130 4.765739
AMY.06 Amygdala | Late midfetal 1811 4.625203
AMY.03 Amygdala | Early fetal 2 1999 4.612301
A1C.13 Primary auditory cortex | Young adulthood 202 4.509279
STR.06 Striatum | Late midfetal 2310 4.295315
MD.08 Mediodorsal nucleus of thalamus | Neonatal early infancy 1845 4.247658
CBC.09 Cerebellar cortex | Late infancy 1518 4.057088
AMY.05 Amygdala | Early midfetal 2 1075 4.831631
ITC.13 Inferior temporal cortex | Young adulthood 157 4.273172
MFC.15 Medial prefrontal cortex | Late adulthood 522 3.949424
V1C.09 Primary visual cortex | Late infancy 287 4.053195
HIP.10 Hippocampus | Early childhood 768 3.479961
M1C.05 Primary motor cortex | Early midfetal 2 1998 3.162182
V1C.06 Primary visual cortex | Late midfetal 2119 3.1523
AMY.08 Amygdala | Neonatal early infancy 488 3.367188
STR.13 Striatum | Young adulthood 1560 3.237319
CBC.12 Cerebellar cortex | Adolescence 2492 3.069733
VFC.03 Ventrolateral prefrontal cortex | Early fetal 2 1121 3.292921
MFC.14 Medial prefrontal cortex | Middle adulthood 229 3.045863
DFC.08 Dorsolateral prefrontal cortex | Neonatal early infancy 219 3.036274
M1C.08 Primary motor cortex | Neonatal early infancy 197 3.24694
IPC.05 Posterior inferior parietal cortex | Early midfetal 2 855 2.808525
STR.14 Striatum | Middle adulthood 1327 2.557768
VFC.14 Ventrolateral prefrontal cortex | Middle adulthood 171 2.749549
S1C.03 Primary somatosensory cortex | Early fetal 2 2430 2.276129
MD.11 Mediodorsal nucleus of thalamus | Middle late childhood 3098 2.265409
ITC.04 Inferior temporal cortex | Early midfetal 1 964 2.052707
CBC.11 Cerebellar cortex | Middle late childhood 1878 2.129995
DFC.06 Dorsolateral prefrontal cortex | Late midfetal 1153 2.064269
A1C.05 Primary auditory cortex | Early midfetal 2 1865 2.215426
MFC.09 Medial prefrontal cortex | Late infancy 91 1.954585
V1C.11 Primary visual cortex | Middle late childhood 1428 1.772997
OFC.12 Orbital prefrontal cortex | Adolescence 57 1.784496
IPC.13 Posterior inferior parietal cortex | Young adulthood 76 1.697377
V1C.14 Primary visual cortex | Middle adulthood 790 1.874773
ITC.03 Inferior temporal cortex | Early fetal 2 1664 1.449192
DFC.07 Dorsolateral prefrontal cortex | Late fetal 692 1.523317
STC.05 Superior temporal cortex | Early midfetal 2 550 1.532816
CNV ?Genomic location ?Number of genes ?ASD frequency ?