GO:0007194 negative regulation of adenylate cyclase activity (55)

GeneInput weightStandardRank
GABBR20.25142
GRM70.251137
ADCY2--175
SSTR2--251
GABBR10.251264
ADCY10.251466
APLP1--591
GRM3--652
GNAZ--856
ADORA1--960
OPRK10.251996
NPY2R0.2511024
GNAL--1177
NPY1R0.2511190
GRIK30.2511247
GNAI3--1262
ADRA2A0.2511399
GRM80.2511404
GNAI1--1468
PALM--1501
GRM2--1757
ADCY9--1850
EDNRB--12042
ADCY8--2785
ADCY6--2877
MCHR10.2512905
HTR1A0.2513315
CHRM50.2513694
DRD20.2513749
FLNA--14285
ADCY5--4295
S1PR1--4301
P2RY1--4342
DRD30.2514349
NPR3--5370
CHRM4--5408
ADCY3--5755
GNAI2--5860
RXFP2--15887
GALR1--5908
OPRD10.2516030
OPRL10.2516271
S1PR3--6774
DRD40.2517021
GRM4--7321
ADCY4--9091
RGS1--10535
PTGDR2--10914
CORT--12689
SSTR50.25114876
LTB4R2--15126
GALR3--15691
INSL3--119059
CCR2--23296
ADCY7--25408

Network

GO:0007194

Network
Enrichment
NameDescriptionExternal IDs
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 Entrez:9568  HPRD: 09552  HGNC: 4507  Ensembl: ENSG00000136928 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HPRD: 04979  HGNC: 4599  Ensembl: ENSG00000196277 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HPRD: 00052  HGNC: 233  Ensembl: ENSG00000078295 
SSTR2somatostatin receptor 2 Entrez:6752  HGNC: 11331  HPRD: 01674 
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1 Entrez:2550  HPRD: 04644  HGNC: 4070  Ensembl: ENSG00000204681 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
GRM7glutamate receptor, metabotropic 7
ADCY2adenylate cyclase 2 (brain)
SSTR2somatostatin receptor 2
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
Query geneGeneGene descriptionEdge score
GABBR2GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
GRM7GRM7glutamate receptor, metabotropic 7
ADCY2ADCY2adenylate cyclase 2 (brain)
SSTR2SSTR2somatostatin receptor 2
GABBR1GABBR1gamma-aminobutyric acid (GABA) B receptor, 1