GO:0045746 negative regulation of Notch signaling pathway (11)

GeneInput weightStandardRank
FBXW7--198
MEG3--238
DLL3--1847
BMP7--1137
HEY1--1280
HEY2--3174
GATA2--13291
NFKBIA--5569
OVOL2--10428
NRARP--14597
C12orf52--24985

Network

GO:0045746

Network
Enrichment
NameDescriptionExternal IDs
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HGNC: 16712  HPRD: 05888  Ensembl: ENSG00000109670 
MEG3maternally expressed 3 (non-protein coding) Entrez:55384  HGNC: 14575  Ensembl: ENSG00000214548 
DLL3delta-like 3 (Drosophila) Entrez:10683  HPRD: 04140  HGNC: 2909  Ensembl: ENSG00000090932 
BMP7bone morphogenetic protein 7 Entrez:655  HPRD: 00212  HGNC: 1074  Ensembl: ENSG00000101144 
HEY1hairy/enhancer-of-split related with YRPW motif 1 Entrez:23462  HPRD: 04260  HGNC: 4880  Ensembl: ENSG00000164683 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
MEG3maternally expressed 3 (non-protein coding)
DLL3delta-like 3 (Drosophila)
BMP7bone morphogenetic protein 7
HEY1hairy/enhancer-of-split related with YRPW motif 1
Query geneGeneGene descriptionEdge score
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
MEG3MEG3maternally expressed 3 (non-protein coding)
DLL3DLL3delta-like 3 (Drosophila)
BMP7BMP7bone morphogenetic protein 7
HEY1HEY1hairy/enhancer-of-split related with YRPW motif 1