GO:0030178 negative regulation of Wnt receptor signaling pathway (83)

GeneInput weightStandardRank
SOX2--1200
FGF9--262
APC0.251266
LRP6--279
SFRP1--387
NLK--712
CSNK1E0.251752
HMGXB4--781
SOX9--1970
APC2--1115
AES--1230
HDAC2--1440
CXXC4--1490
CHD81.011493
LEF1--1499
LRP4--1500
TLE1--1605
GRB10--1910
MED120.2512052
MCC--2167
STK4--2276
DKK2--2331
SIX3--12494
LATS1--2781
CTNND1--2948
EGR1--3062
CITED1--3064
WNT5A--3319
DAB2IP--3482
TCF7L20.513548
SIAH2--3729
SOX17--4024
LECT2--4161
AXIN2--14260
AXIN1--14419
CYLD--14624
DRAXIN--4717
SFRP2--5252
DKK3--5413
PRICKLE1--15552
CTNNBIP1--5675
WWOX--15791
GLI1--6241
GLI3--16261
TLE2--6532
BARX1--6608
SOST--6885
SCYL2--7130
SFRP4--7310
WNT8A--7814
WNT11--7820
FRZB--8105
GPC3--18430
NKX2-50.2518486
TBX18--8991
TSC20.2519351
GSC--9702
LATS2--9736
DKK4--10367
APCDD1--10507
SFRP5--11273
DKK1--11567
NPHP3--113474
MDFI--13519
MESP1--13805
INVS--114708
DDIT3--14883
WNT5B--15534
TAX1BP3--15553
SHH--118571
FZD6--19921
JUP--120291
FZD1--20775
STK3--21167
WNT4--21809
LRP1--22276
PFDN5--23272
GNB2L1--23282
CBY1--23816
SNAI2--123962
WWTR1--24317
DAB2--25338
CAV1--125381

Network

GO:0030178

Network
Enrichment
NameDescriptionExternal IDs
SOX2SRY (sex determining region Y)-box 2 Entrez:6657  HPRD: 08921  HGNC: 11195  Ensembl: ENSG00000181449 
FGF9fibroblast growth factor 9 Entrez:2254  HGNC: 3687  HPRD: 02951  Ensembl: ENSG00000102678 
APCadenomatous polyposis coli Entrez:324  HPRD: 01439  HGNC: 583  Ensembl: ENSG00000134982 
LRP6low density lipoprotein receptor-related protein 6 Entrez:4040  HPRD: 04617  HGNC: 6698  Ensembl: ENSG00000070018 
SFRP1secreted frizzled-related protein 1 Entrez:6422  HGNC: 10776  HPRD: 09165  Ensembl: ENSG00000104332 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SOX2SRY (sex determining region Y)-box 2
FGF9fibroblast growth factor 9
APCadenomatous polyposis coli
LRP6low density lipoprotein receptor-related protein 6
SFRP1secreted frizzled-related protein 1
Query geneGeneGene descriptionEdge score
SOX2SOX2SRY (sex determining region Y)-box 2
FGF9FGF9fibroblast growth factor 9
APCAPCadenomatous polyposis coli
LRP6LRP6low density lipoprotein receptor-related protein 6
SFRP1SFRP1secreted frizzled-related protein 1