GO:0000186 activation of MAPKK activity (43)

GeneInput weightStandardRank
KRAS--157
YWHAB0.251107
KIDINS220--701
MAP2K10.251907
ADORA1--960
GRM10.251975
MAPK1--1128
MAP3K5--1220
MAP2K20.2511240
MAP3K7--1275
TNIK--1531
TAOK20.2511633
CARTPT0.2511957
MAPKBP1--2654
CRK--2713
MAP3K13--2864
RAF10.2513236
MAP3K1--13381
MAP3K4--3663
FLT10.2513953
HRAS0.2515086
GNAI2--5860
NGF0.2516229
MAPK30.2516426
BMP4--16499
FRS2--7173
TGFBR1--17268
RAPGEF1--7926
GADD45B--8312
NTRK10.2518522
LAMTOR2--8770
LRRK2--18802
KISS1R--9434
BRAF--111149
EGF0.25112881
MAP3K11--12938
RAP1A--13091
FGF2--13150
NRAS--114119
PSEN1--18523
F2R--20036
CDK1--25053
ADAM9--125221

Network

GO:0000186

Network
Enrichment
NameDescriptionExternal IDs
KRASKirsten rat sarcoma viral oncogene homolog Entrez:3845  HPRD: 01817  HGNC: 6407  Ensembl: ENSG00000133703 
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HPRD: 03184  HGNC: 12849  Ensembl: ENSG00000166913 
KIDINS220kinase D-interacting substrate, 220kDa Entrez:57498  HGNC: 29508  HPRD: 17235  Ensembl: ENSG00000134313 
MAP2K1mitogen-activated protein kinase kinase 1 Entrez:5604  HPRD: 01469  HGNC: 6840 
ADORA1adenosine A1 receptor Entrez:134  HGNC: 262  HPRD: 00042  Ensembl: ENSG00000163485 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
KRASKirsten rat sarcoma viral oncogene homolog
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
KIDINS220kinase D-interacting substrate, 220kDa
MAP2K1mitogen-activated protein kinase kinase 1
ADORA1adenosine A1 receptor
Query geneGeneGene descriptionEdge score
KRASKRASKirsten rat sarcoma viral oncogene homolog
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
KIDINS220KIDINS220kinase D-interacting substrate, 220kDa
MAP2K1MAP2K1mitogen-activated protein kinase kinase 1
ADORA1ADORA1adenosine A1 receptor