GO:0042058 regulation of epidermal growth factor receptor signaling pathway (59)

GeneInput weightStandardRank
HGS--152
FBXW7--198
AP2S1--210
ARHGEF7--215
SH3GL2--454
AP2M1--779
ADORA1--960
CDC42--1138
ADRA2A0.2511399
SPRY2--1454
CBL--1478
CLTA--1495
APP--1515
CDH13--1692
ESR10.2511791
TGFA--1873
CLTC--1904
EPS15L1--2046
AP2A2--2352
EGFR--12546
GRB2--2962
NCK2--3077
DAB2IP--3482
PDE6H--4126
SH3KBP1--4166
AP2A1--4845
PTPRF--5040
EPS15--5197
ADAM17--5323
FASLG--15523
ERRFI1--6649
UBC--6756
AP2B1--6850
STAM--7024
ZFYVE28--7781
ADRA2C--8551
NUP62--18755
EREG--9052
PTPRJ--19136
GPER1--9912
SHC1--10045
ADRA2B--10119
AFAP1L2--10424
SPRY1--10636
EPGN--12503
EGF0.25112881
AGT--113305
PSEN1--18523
UBB--19448
EPN1--19827
PDE6G--120364
ZGPAT--20366
CBLC--21497
SNX6--22713
RHBDF1--23088
PSEN2--23095
STAM2--23860
RPS27A--24381
UBA52--24384

Network

GO:0042058

Network
Enrichment
NameDescriptionExternal IDs
HGShepatocyte growth factor-regulated tyrosine kinase substrate Entrez:9146  HGNC: 4897  HPRD: 05085  Ensembl: ENSG00000185359 
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase Entrez:55294  HGNC: 16712  HPRD: 05888  Ensembl: ENSG00000109670 
AP2S1adaptor-related protein complex 2, sigma 1 subunit Entrez:1175  HGNC: 565  HPRD: 03762  Ensembl: ENSG00000042753 
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7 Entrez:8874  HPRD: 05688  HGNC: 15607  Ensembl: ENSG00000102606 
SH3GL2SH3-domain GRB2-like 2 Entrez:6456  HPRD: 05125  HGNC: 10831  Ensembl: ENSG00000107295 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HGShepatocyte growth factor-regulated tyrosine kinase substrate
FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
AP2S1adaptor-related protein complex 2, sigma 1 subunit
ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7
SH3GL2SH3-domain GRB2-like 2
Query geneGeneGene descriptionEdge score
HGSHGShepatocyte growth factor-regulated tyrosine kinase substrate
FBXW7FBXW7F-box and WD repeat domain containing 7, E3 ubiquitin protein ligase
AP2S1AP2S1adaptor-related protein complex 2, sigma 1 subunit
ARHGEF7ARHGEF7Rho guanine nucleotide exchange factor (GEF) 7
SH3GL2SH3GL2SH3-domain GRB2-like 2