GO:0051967 negative regulation of synaptic transmission, glutamatergic (7)

GeneInput weightStandardRank
HTR2A0.251121
GRIK20.51232
GRIK1--481
ADORA1--960
GRIK30.2511247
DRD20.2513749
HTR1B0.2518092

Network

GO:0051967

Network
Enrichment
NameDescriptionExternal IDs
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HGNC: 5293  HPRD: 01638  Ensembl: ENSG00000102468 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  HPRD: 00692  HGNC: 4580  Ensembl: ENSG00000164418 
GRIK1glutamate receptor, ionotropic, kainate 1 Entrez:2897  HPRD: 00693  HGNC: 4579  Ensembl: ENSG00000171189 
ADORA1adenosine A1 receptor Entrez:134  HGNC: 262  HPRD: 00042  Ensembl: ENSG00000163485 
GRIK3glutamate receptor, ionotropic, kainate 3 Entrez:2899  HPRD: 00691  HGNC: 4581  Ensembl: ENSG00000163873 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRIK2glutamate receptor, ionotropic, kainate 2
GRIK1glutamate receptor, ionotropic, kainate 1
ADORA1adenosine A1 receptor
GRIK3glutamate receptor, ionotropic, kainate 3
Query geneGeneGene descriptionEdge score
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
GRIK1GRIK1glutamate receptor, ionotropic, kainate 1
ADORA1ADORA1adenosine A1 receptor
GRIK3GRIK3glutamate receptor, ionotropic, kainate 3