GO:0030509 BMP signaling pathway (45)

GeneInput weightStandardRank
BMPR2--1281
UBE2D3--528
USP9X--554
SMAD4--821
SMURF2--889
CHRD--941
ACVR2A--965
SMAD5--1002
BMP7--1137
BMPR1A--1140
SMAD7--1192
LEF1--1499
ACVR2B--11676
SMAD1--1872
MSX2--12260
GDF6--12291
SMAD6--2305
BMPR1B--12316
CHRDL1--2383
GREM2--2664
RGMB--2696
SKI--2904
SMURF1--3060
EGR1--3062
MSX1--13127
SMAD9--13672
BMP6--4358
BMP2--14855
BMP10--5102
NOG--15439
ZFYVE16--5592
ACVR1--16054
BMP4--16499
USP9Y--16508
TGFBR3--6672
GDF7--6682
CER1--6956
ID1--9040
FSTL1--14291
GDF2--14603
FST--14783
POU5F1--19704
ECSIT--22627
ENG--124746
UBE2D1--24988

Network

GO:0030509

Network
Enrichment
NameDescriptionExternal IDs
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase) Entrez:659  HGNC: 1078  HPRD: 02880  Ensembl: ENSG00000204217 
UBE2D3ubiquitin-conjugating enzyme E2D 3 Entrez:7323  HGNC: 12476  HPRD: 04269  Ensembl: ENSG00000109332 
USP9Xubiquitin specific peptidase 9, X-linked Entrez:8239  HPRD: 02091  HGNC: 12632  Ensembl: ENSG00000124486 
SMAD4SMAD family member 4 Entrez:4089  HPRD: 02995  HGNC: 6770  Ensembl: ENSG00000141646 
SMURF2SMAD specific E3 ubiquitin protein ligase 2 Entrez:64750  HPRD: 06901  HGNC: 16809 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
UBE2D3ubiquitin-conjugating enzyme E2D 3
USP9Xubiquitin specific peptidase 9, X-linked
SMAD4SMAD family member 4
SMURF2SMAD specific E3 ubiquitin protein ligase 2
Query geneGeneGene descriptionEdge score
BMPR2BMPR2bone morphogenetic protein receptor, type II (serine/threonine kinase)
UBE2D3UBE2D3ubiquitin-conjugating enzyme E2D 3
USP9XUSP9Xubiquitin specific peptidase 9, X-linked
SMAD4SMAD4SMAD family member 4
SMURF2SMURF2SMAD specific E3 ubiquitin protein ligase 2