GO:0008629 induction of apoptosis by intracellular signals (82)

GeneInput weightStandardRank
YWHAB0.251107
EP300--1318
PPP3R1--321
CUL1--478
PPP2R5C--555
TOPORS--1894
RYR2--1959
AKT10.2511020
HIPK2--1051
CUL31.011093
DYNLL1--1191
DYRK2--1203
MAPK8--1214
BAD--1290
BAG6--1305
CUL2--2097
CUL5--2323
ABL1--2404
BCL20.2512485
FNIP2--3028
MSH6--13445
BCL2L11--3469
ATM--13622
HRAS0.2515086
APAF10.2515149
XPA--15296
STK11--16000
CIDEA--6211
MSH2--16311
BMF--6376
BCL2L1--6563
PCBP4--6634
CASP30.2516694
BNIP3--6953
XIAP--7332
PMAIP1--7385
CDIP1--7580
CDKN1A--7714
BCL3--7998
CD24--18102
NMT1--8219
CYCS--9251
BOK--9611
BAX--9833
MBD40.25110712
GPX10.25111644
UACA--12955
PRODH0.25114818
USP28--15068
SIK1--15416
PPP3CC--16922
TP530.25118277
TP73--18810
LGALS12--19322
BBC3--20534
GZMB--20809
SART1--20962
CASP90.25121044
DYNLL2--21102
BAK1--21229
AEN--22019
TP63--122528
BID--22640
DIABLO--23456
TP53I3--23611
HMOX1--23938
RNF7--23982
CIDEB--24163
CUL4A--24230
IFI16--24354
BRCA1--124573
CASP8--124587
IKBKE--24643
CHEK2--124807
HTRA2--124821
PHLDA3--24856
CASP7--25028
RPS27L--25183
PML--25277
SFN--25459
MLH1--125513
AIFM1--25591

Network

GO:0008629

Network
Enrichment
NameDescriptionExternal IDs
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide Entrez:7529  HPRD: 03184  HGNC: 12849  Ensembl: ENSG00000166913 
EP300E1A binding protein p300 Entrez:2033  HPRD: 04078  HGNC: 3373  Ensembl: ENSG00000100393 
PPP3R1protein phosphatase 3, regulatory subunit B, alpha Entrez:5534  HGNC: 9317  HPRD: 03195  Ensembl: ENSG00000221823 
CUL1cullin 1 Entrez:8454  HPRD: 04389  HGNC: 2551  Ensembl: ENSG00000055130 
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma Entrez:5527  HGNC: 9311  HPRD: 03385  Ensembl: ENSG00000078304 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
YWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
EP300E1A binding protein p300
PPP3R1protein phosphatase 3, regulatory subunit B, alpha
CUL1cullin 1
PPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma
Query geneGeneGene descriptionEdge score
YWHABYWHABtyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
EP300EP300E1A binding protein p300
PPP3R1PPP3R1protein phosphatase 3, regulatory subunit B, alpha
CUL1CUL1cullin 1
PPP2R5CPPP2R5Cprotein phosphatase 2, regulatory subunit B', gamma