GO:0043551 regulation of phosphatidylinositol 3-kinase activity (14)

GeneInput weightStandardRank
PIK3R10.251150
CDC42--1138
IRS1--11374
RAC1--1617
VAV2--2850
VAV3--2908
FGF2--13150
CCL19--14578
PIK3R5--19487
TGFB10.25120135
PDGFB--21071
NOD2--121514
CCL21--21829
CCR7--22367

Network

GO:0043551

Network
Enrichment
NameDescriptionExternal IDs
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HPRD: 01381  HGNC: 8979  Ensembl: ENSG00000145675 
CDC42cell division cycle 42 Entrez:998  HGNC: 1736  HPRD: 00309  Ensembl: ENSG00000070831 
IRS1insulin receptor substrate 1 Entrez:3667  HGNC: 6125  HPRD: 00943 
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) Entrez:5879  HGNC: 9801  HPRD: 03627  Ensembl: ENSG00000136238 
VAV2vav 2 guanine nucleotide exchange factor Entrez:7410  HPRD: 02694  HGNC: 12658  Ensembl: ENSG00000160293 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
CDC42cell division cycle 42
IRS1insulin receptor substrate 1
RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
VAV2vav 2 guanine nucleotide exchange factor
Query geneGeneGene descriptionEdge score
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
CDC42CDC42cell division cycle 42
IRS1IRS1insulin receptor substrate 1
RAC1RAC1ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)
VAV2VAV2vav 2 guanine nucleotide exchange factor