GO:0014067 negative regulation of phosphatidylinositol 3-kinase cascade (7)

GeneInput weightStandardRank
NCOR1--1019
KLF4--3609
SERPINE2--3708
SLC9A3R2--5711
TWIST1--16980
TSC20.2519351
SLC9A3R1--21898

Network

GO:0014067

Network
Enrichment
NameDescriptionExternal IDs
NCOR1nuclear receptor corepressor 1 Entrez:9611  HGNC: 7672  HPRD: 02911  Ensembl: ENSG00000141027 
KLF4Kruppel-like factor 4 (gut) Entrez:9314  HGNC: 6348  Ensembl: ENSG00000136826 
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 Entrez:5270  HPRD: 01510  HGNC: 8951  Ensembl: ENSG00000135919 
SLC9A3R2solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2 Entrez:9351  HGNC: 11076  HPRD: 05946  Ensembl: ENSG00000065054 
TWIST1twist basic helix-loop-helix transcription factor 1 Entrez:7291  HGNC: 12428  HPRD: 03374  Ensembl: ENSG00000122691 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NCOR1nuclear receptor corepressor 1
KLF4Kruppel-like factor 4 (gut)
SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC9A3R2solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
TWIST1twist basic helix-loop-helix transcription factor 1
Query geneGeneGene descriptionEdge score
NCOR1NCOR1nuclear receptor corepressor 1
KLF4KLF4Kruppel-like factor 4 (gut)
SERPINE2SERPINE2serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2
SLC9A3R2SLC9A3R2solute carrier family 9, subfamily A (NHE3, cation proton antiporter 3), member 3 regulator 2
TWIST1TWIST1twist basic helix-loop-helix transcription factor 1