GO:0006265 DNA topological change (9)

GeneInput weightStandardRank
TOP1--308
TOP2B--615
HMGB10.2512379
HMGB2--3362
ERCC3--17110
TOP3B--10706
TOP1MT--22926
TOP3A--23752
TOP2A--24765

Network

GO:0006265

Network
Enrichment
NameDescriptionExternal IDs
TOP1topoisomerase (DNA) I Entrez:7150  HPRD: 00535  HGNC: 11986  Ensembl: ENSG00000198900 
TOP2Btopoisomerase (DNA) II beta 180kDa Entrez:7155  HPRD: 00537  HGNC: 11990  Ensembl: ENSG00000077097 
HMGB1high mobility group box 1 Entrez:3146  HPRD: 01228  HGNC: 4983  Ensembl: ENSG00000189403 
HMGB2high mobility group box 2 Entrez:3148  HPRD: 01229  HGNC: 5000 
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3 Entrez:2071  HPRD: 00593  HGNC: 3435  Ensembl: ENSG00000163161 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
TOP1topoisomerase (DNA) I
TOP2Btopoisomerase (DNA) II beta 180kDa
HMGB1high mobility group box 1
HMGB2high mobility group box 2
ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3
Query geneGeneGene descriptionEdge score
TOP1TOP1topoisomerase (DNA) I
TOP2BTOP2Btopoisomerase (DNA) II beta 180kDa
HMGB1HMGB1high mobility group box 1
HMGB2HMGB2high mobility group box 2
ERCC3ERCC3excision repair cross-complementing rodent repair deficiency, complementation group 3