GO:0030579 ubiquitin-dependent SMAD protein catabolic process (5)

GeneInput weightStandardRank
SMURF2--889
SMURF1--3060
STUB1--4250
WNT1--4383
TGFB1I1--23709

Network

GO:0030579

Network
Enrichment
NameDescriptionExternal IDs
SMURF2SMAD specific E3 ubiquitin protein ligase 2 Entrez:64750  HPRD: 06901  HGNC: 16809 
SMURF1SMAD specific E3 ubiquitin protein ligase 1 Entrez:57154  HGNC: 16807  HPRD: 06902  Ensembl: ENSG00000198742 
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase Entrez:10273  HPRD: 06232  HGNC: 11427  Ensembl: ENSG00000103266 
WNT1wingless-type MMTV integration site family, member 1 Entrez:7471  HPRD: 01276  HGNC: 12774 
TGFB1I1transforming growth factor beta 1 induced transcript 1 Entrez:7041  HPRD: 03831  HGNC: 11767  Ensembl: ENSG00000140682 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
SMURF2SMAD specific E3 ubiquitin protein ligase 2
SMURF1SMAD specific E3 ubiquitin protein ligase 1
STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
WNT1wingless-type MMTV integration site family, member 1
TGFB1I1transforming growth factor beta 1 induced transcript 1
Query geneGeneGene descriptionEdge score
SMURF2SMURF2SMAD specific E3 ubiquitin protein ligase 2
SMURF1SMURF1SMAD specific E3 ubiquitin protein ligase 1
STUB1STUB1STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase
WNT1WNT1wingless-type MMTV integration site family, member 1
TGFB1I1TGFB1I1transforming growth factor beta 1 induced transcript 1