GO:0032232 negative regulation of actin filament bundle assembly (6)

GeneInput weightStandardRank
PARK20.251952
DLC1--1282
MAP3K1--13381
S1PR1--4301
ARHGAP6--5374
ARAP1--24899

Network

GO:0032232

Network
Enrichment
NameDescriptionExternal IDs
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin) Entrez:5071  HGNC: 8607  HPRD: 03967  Ensembl: ENSG00000185345 
DLC1deleted in liver cancer 1 Entrez:10395  HGNC: 2897  HPRD: 05035  Ensembl: ENSG00000164741 
MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase Entrez:4214  HGNC: 6848  Ensembl: ENSG00000095015 
S1PR1sphingosine-1-phosphate receptor 1 Entrez:1901  HPRD: 03578  HGNC: 3165  Ensembl: ENSG00000170989 
ARHGAP6Rho GTPase activating protein 6 Entrez:395  HGNC: 676  HPRD: 02124  Ensembl: ENSG00000047648 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
DLC1deleted in liver cancer 1
MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
S1PR1sphingosine-1-phosphate receptor 1
ARHGAP6Rho GTPase activating protein 6
Query geneGeneGene descriptionEdge score
PARK2PARK2parkinson protein 2, E3 ubiquitin protein ligase (parkin)
DLC1DLC1deleted in liver cancer 1
MAP3K1MAP3K1mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase
S1PR1S1PR1sphingosine-1-phosphate receptor 1
ARHGAP6ARHGAP6Rho GTPase activating protein 6