GO:0051899 membrane depolarization (44)

GeneInput weightStandardRank
NRXN11.012
ATXN1--15
GRIN2A0.25166
GRIK20.51232
PPP3CA--244
CACNA1A--1270
CACNB4--271
NLGN10.251276
CACNB3--278
GRIN1--294
MAPK8IP2--418
JUN--511
CACNA1B--593
CACNA1E--612
SNCA--1667
ADORA1--960
CHRNA3--1266
CACNG4--1342
CACNG2--1460
SPECC1L--1912
NLGN4X1.012439
CDK50.2513194
GRID20.2513225
PARK7--13322
CHRNA6--4229
CHRNA40.2514471
GRIN2C--5801
ADIPOQ0.2516032
KCNQ1--17724
P2RX7--7888
ADORA2A0.2518408
AIFM3--8980
GHRL0.2519242
KCNE1--19266
EDN1--9540
BEST2--10624
HCRT0.25111633
DMPK0.25112484
MTMR2--113176
CHRNB20.25120216
P2RX4--22325
ADRB20.25123251
SLC29A1--24079
CAV1--125381

Network

GO:0051899

Network
Enrichment
NameDescriptionExternal IDs
NRXN1neurexin 1 Entrez:9378  HGNC: 8008  HPRD: 11858  Ensembl: ENSG00000179915 
ATXN1ataxin 1 Entrez:6310  HGNC: 10548  HPRD: 03333  Ensembl: ENSG00000124788 
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A Entrez:2903  HPRD: 00698  HGNC: 4585  Ensembl: ENSG00000183454 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  HPRD: 00692  HGNC: 4580  Ensembl: ENSG00000164418 
PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme Entrez:5530  HPRD: 00234  HGNC: 9314  Ensembl: ENSG00000138814 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NRXN1neurexin 1
ATXN1ataxin 1
GRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIK2glutamate receptor, ionotropic, kainate 2
PPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme
Query geneGeneGene descriptionEdge score
NRXN1NRXN1neurexin 1
ATXN1ATXN1ataxin 1
GRIN2AGRIN2Aglutamate receptor, ionotropic, N-methyl D-aspartate 2A
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
PPP3CAPPP3CAprotein phosphatase 3, catalytic subunit, alpha isozyme