GO:0007224 smoothened signaling pathway (33)

GeneInput weightStandardRank
HIPK1--311
PAX60.251544
PTCH1--1972
HIPK2--1051
NKX2-2--1120
DYRK2--1203
WNT10B--1517
PTCHD11.012465
TULP3--2770
MAP3K10--2968
CDON--3487
FOXF1--13518
NKX6-1--4665
HES5--4919
NDST1--5114
HES10.2515912
GLI3--16261
BMP4--16499
BOC--6901
GLI2--17307
PTCHD2--8030
DISP2--8238
TGFBR2--110407
SMO0.25110504
TCTN2--11040
IFT88--12504
HHAT--13234
IFT52--16599
SHH--118571
STK36--21217
IFT172--22658
DISP1--22983
NSDHL--23481

Network

GO:0007224

Network
Enrichment
NameDescriptionExternal IDs
HIPK1homeodomain interacting protein kinase 1 Entrez:204851  HPRD: 06418  HGNC: 19006  Ensembl: ENSG00000163349 
PAX6paired box 6 Entrez:5080  HGNC: 8620  HPRD: 06167  Ensembl: ENSG00000007372 
PTCH1patched 1 Entrez:5727  HPRD: 03200  HGNC: 9585  Ensembl: ENSG00000185920 
HIPK2homeodomain interacting protein kinase 2 Entrez:28996  HGNC: 14402  HPRD: 06039  Ensembl: ENSG00000064393 
NKX2-2NK2 homeobox 2 Entrez:4821  HPRD: 05213  HGNC: 7835  Ensembl: ENSG00000125820 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HIPK1homeodomain interacting protein kinase 1
PAX6paired box 6
PTCH1patched 1
HIPK2homeodomain interacting protein kinase 2
NKX2-2NK2 homeobox 2
Query geneGeneGene descriptionEdge score
HIPK1HIPK1homeodomain interacting protein kinase 1
PAX6PAX6paired box 6
PTCH1PTCH1patched 1
HIPK2HIPK2homeodomain interacting protein kinase 2
NKX2-2NKX2-2NK2 homeobox 2