GO:0046426 negative regulation of JAK-STAT cascade (9)

GeneInput weightStandardRank
PPP2CA--20
NEUROD1--1127
HGS--152
PPP2R1A--1163
NF2--15991
SOCS1--9583
IRF1--111641
HNF4A--122965
CAV1--125381

Network

GO:0046426

Network
Enrichment
NameDescriptionExternal IDs
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme Entrez:5515  HPRD: 08912  HGNC: 9299 
NEUROD1neuronal differentiation 1 Entrez:4760  HGNC: 7762  HPRD: 03428  Ensembl: ENSG00000162992 
HGShepatocyte growth factor-regulated tyrosine kinase substrate Entrez:9146  HGNC: 4897  HPRD: 05085  Ensembl: ENSG00000185359 
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha Entrez:5518  HGNC: 9302  HPRD: 16184 
NF2neurofibromin 2 (merlin) Entrez:4771  HPRD: 06980  HGNC: 7773  Ensembl: ENSG00000186575 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
NEUROD1neuronal differentiation 1
HGShepatocyte growth factor-regulated tyrosine kinase substrate
PPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha
NF2neurofibromin 2 (merlin)
Query geneGeneGene descriptionEdge score
PPP2CAPPP2CAprotein phosphatase 2, catalytic subunit, alpha isozyme
NEUROD1NEUROD1neuronal differentiation 1
HGSHGShepatocyte growth factor-regulated tyrosine kinase substrate
PPP2R1APPP2R1Aprotein phosphatase 2, regulatory subunit A, alpha
NF2NF2neurofibromin 2 (merlin)