GO:0050805 negative regulation of synaptic transmission (33)

GeneInput weightStandardRank
ADNP1.0171
HTR2A0.251121
GRIK20.51232
GABBR10.251264
SLC6A10.251313
GRIK1--481
NPY5R0.251725
STXBP1--769
DRD10.251899
RAPGEF40.251904
ADORA1--960
DRD50.2511103
GRIK30.2511247
GNAI3--1262
GNAI1--1468
ADRA1A--1858
ACHE--2025
SLC24A2--2302
BCHE--2809
DRD20.2513749
TNR--3868
SLC6A40.2514137
PTGS20.2515085
GNAI2--5860
ADIPOQ0.2516032
HTR1B0.2518092
ABHD6--10063
CNR20.25111649
PMCH--12542
KCNQ4--112849
MGLL--14193
GRID2IP--21156
CD380.25121442

Network

GO:0050805

Network
Enrichment
NameDescriptionExternal IDs
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  HGNC: 15766  HPRD: 09793  Ensembl: ENSG00000101126 
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HGNC: 5293  HPRD: 01638  Ensembl: ENSG00000102468 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  HPRD: 00692  HGNC: 4580  Ensembl: ENSG00000164418 
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1 Entrez:2550  HPRD: 04644  HGNC: 4070  Ensembl: ENSG00000204681 
SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1 Entrez:6529  HPRD: 00664  HGNC: 11042  Ensembl: ENSG00000157103 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
ADNPactivity-dependent neuroprotector homeobox
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRIK2glutamate receptor, ionotropic, kainate 2
GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1
Query geneGeneGene descriptionEdge score
ADNPADNPactivity-dependent neuroprotector homeobox
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
GABBR1GABBR1gamma-aminobutyric acid (GABA) B receptor, 1
SLC6A1SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1