GO:0048009 insulin-like growth factor receptor signaling pathway (13)

GeneInput weightStandardRank
PLCB1--148
PIK3R10.251150
IGF1R--252
AKT10.2511020
IRS1--11374
GRB10--1910
GIGYF2--12267
CRIM1--2697
GIGYF10.519180
TSC20.2519351
GHR--110098
IGF2R--12308
EIF2AK3--20456

Network

GO:0048009

Network
Enrichment
NameDescriptionExternal IDs
PLCB1phospholipase C, beta 1 (phosphoinositide-specific) Entrez:23236  HPRD: 06177  HGNC: 15917  Ensembl: ENSG00000182621 
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Entrez:5295  HPRD: 01381  HGNC: 8979  Ensembl: ENSG00000145675 
IGF1Rinsulin-like growth factor 1 receptor Entrez:3480  HGNC: 5465  HPRD: 00932  Ensembl: ENSG00000140443 
AKT1v-akt murine thymoma viral oncogene homolog 1 Entrez:207  HGNC: 391  HPRD: 01261  Ensembl: ENSG00000142208 
IRS1insulin receptor substrate 1 Entrez:3667  HGNC: 6125  HPRD: 00943 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
IGF1Rinsulin-like growth factor 1 receptor
AKT1v-akt murine thymoma viral oncogene homolog 1
IRS1insulin receptor substrate 1
Query geneGeneGene descriptionEdge score
PLCB1PLCB1phospholipase C, beta 1 (phosphoinositide-specific)
PIK3R1PIK3R1phosphoinositide-3-kinase, regulatory subunit 1 (alpha)
IGF1RIGF1Rinsulin-like growth factor 1 receptor
AKT1AKT1v-akt murine thymoma viral oncogene homolog 1
IRS1IRS1insulin receptor substrate 1