GO:0031281 positive regulation of cyclase activity (63)

GeneInput weightStandardRank
NTRK20.25128
ADCY2--102
ADCYAP1--127
CRHR1--280
NF10.251333
CALCA--460
ADCY10.251466
DRD50.251482
GNAQ--490
FSHR--1648
DRD10.251662
GNAL--860
ADRB1--866
CAP1--1037
ADCYAP1R1--1132
CAP2--1213
PTHLH--11269
VIPR2--1327
HTR70.2511529
ADRB3--11787
ADCY8--1906
CALCR--2247
GHRHR--2312
GNAS--12352
LHCGR0.2512362
ADCY9--2435
DRD30.2512757
HTR4--2810
RXFP1--2904
SPECC1L--3048
TSHR--3078
CALCRL0.2513258
EDNRA--13271
GCGR--13430
ACR--4233
ADCY5--4352
ADCY6--4362
GPR3--4384
AVPR2--14537
GHRH--4568
ADCY3--4618
ADORA3--4733
NTRK10.2514883
PTH--5481
GALR1--5954
GPR26--6001
RXFP2--16360
GLP1R--7291
ADCY4--8354
GIPR--9148
ADORA2A0.2519605
UCN3--9836
ADORA2B--11164
NOS3--12710
GALR2--12784
ADM2--15430
P2RY11--18359
GPR78--19507
GNA13--20348
SLC9A3R1--21807
S1PR4--22365
ADRB20.25122718
ADCY7--25198

Network

GO:0031281

Network
Enrichment
NameDescriptionExternal IDs
NTRK2neurotrophic tyrosine kinase, receptor, type 2 Entrez:4915  HGNC: 8032  HPRD: 02712  Ensembl: ENSG00000148053 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HPRD: 00052  HGNC: 233  Ensembl: ENSG00000078295 
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary) Entrez:116  HPRD: 02369  HGNC: 241  Ensembl: ENSG00000141433 
CRHR1corticotropin releasing hormone receptor 1 Entrez:1394  HPRD: 08830  HGNC: 2357  Ensembl: ENSG00000120088 
NF1neurofibromin 1 Entrez:4763  HPRD: 01203  HGNC: 7765  Ensembl: ENSG00000196712 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
NTRK2neurotrophic tyrosine kinase, receptor, type 2
ADCY2adenylate cyclase 2 (brain)
ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
CRHR1corticotropin releasing hormone receptor 1
NF1neurofibromin 1
Query geneGeneGene descriptionEdge score
NTRK2NTRK2neurotrophic tyrosine kinase, receptor, type 2
ADCY2ADCY2adenylate cyclase 2 (brain)
ADCYAP1ADCYAP1adenylate cyclase activating polypeptide 1 (pituitary)
CRHR1CRHR1corticotropin releasing hormone receptor 1
NF1NF1neurofibromin 1