GO:0050805 negative regulation of synaptic transmission (33)

GeneInput weightStandardRank
HTR2A0.25151
ADNP0.5191
GRIK20.51142
GRIK1--216
SLC6A10.251238
GABBR10.251352
DRD50.251482
ADORA1--498
NPY5R0.251512
RAPGEF40.251635
STXBP1--659
DRD10.251662
ADRA1A--937
GRIK30.251976
ACHE--1266
GNAI3--1340
GNAI1--1613
SLC24A2--1691
DRD20.2512071
BCHE--2123
TNR--2784
PTGS20.2513176
SLC6A40.2513328
ADIPOQ0.2514834
HTR1B0.2515751
GNAI2--6384
ABHD6--7605
CNR20.2518581
MGLL--10038
PMCH--11242
CD380.25117453
KCNQ4--120957
GRID2IP--22273

Network

GO:0050805

Network
Enrichment
NameDescriptionExternal IDs
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled Entrez:3356  HGNC: 5293  HPRD: 01638  Ensembl: ENSG00000102468 
ADNPactivity-dependent neuroprotector homeobox Entrez:23394  HGNC: 15766  HPRD: 09793  Ensembl: ENSG00000101126 
GRIK2glutamate receptor, ionotropic, kainate 2 Entrez:2898  HPRD: 00692  HGNC: 4580  Ensembl: ENSG00000164418 
GRIK1glutamate receptor, ionotropic, kainate 1 Entrez:2897  HPRD: 00693  HGNC: 4579  Ensembl: ENSG00000171189 
SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1 Entrez:6529  HPRD: 00664  HGNC: 11042  Ensembl: ENSG00000157103 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
HTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ADNPactivity-dependent neuroprotector homeobox
GRIK2glutamate receptor, ionotropic, kainate 2
GRIK1glutamate receptor, ionotropic, kainate 1
SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1
Query geneGeneGene descriptionEdge score
HTR2AHTR2A5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled
ADNPADNPactivity-dependent neuroprotector homeobox
GRIK2GRIK2glutamate receptor, ionotropic, kainate 2
GRIK1GRIK1glutamate receptor, ionotropic, kainate 1
SLC6A1SLC6A1solute carrier family 6 (neurotransmitter transporter), member 1