GO:0051350 negative regulation of lyase activity (55)

GeneInput weightStandardRank
GABBR20.25141
ADCY2--102
GRM70.251147
SSTR2--185
APLP1--335
GABBR10.251352
GRM3--399
ADCY10.251466
ADORA1--498
NPY2R0.251597
GNAZ--618
OPRK10.251764
GNAL--860
GRIK30.251976
FLNA--1984
NPY1R0.2511012
GRM80.2511152
EDNRB--11322
GNAI3--1340
PALM--1349
GRM2--1421
ADRA2A0.2511556
GNAI1--1613
HTR1A0.2511672
ADCY8--1906
MCHR10.2512005
DRD20.2512071
CHRM50.2512290
ADCY9--2435
DRD30.2512757
S1PR1--2910
OPRD10.2513266
NPR3--3798
ADCY5--4352
ADCY6--4362
CHRM4--4460
P2RY1--4483
ADCY3--4618
GRM4--5804
GALR1--5954
RXFP2--16360
GNAI2--6384
S1PR3--6584
DRD40.2517058
RGS1--7315
OPRL10.2518293
ADCY4--8354
SSTR50.2519084
PTGDR2--9477
CORT--11364
INSL3--111614
LTB4R2--13227
GALR3--15944
CCR2--22318
ADCY7--25198

Network

GO:0051350

Network
Enrichment
NameDescriptionExternal IDs
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2 Entrez:9568  HPRD: 09552  HGNC: 4507  Ensembl: ENSG00000136928 
ADCY2adenylate cyclase 2 (brain) Entrez:108  HPRD: 00052  HGNC: 233  Ensembl: ENSG00000078295 
GRM7glutamate receptor, metabotropic 7 Entrez:2917  HPRD: 04979  HGNC: 4599  Ensembl: ENSG00000196277 
SSTR2somatostatin receptor 2 Entrez:6752  HGNC: 11331  HPRD: 01674 
APLP1amyloid beta (A4) precursor-like protein 1 Entrez:333  HPRD: 00102  HGNC: 597  Ensembl: ENSG00000105290 
GenesetTypeFreq. (Network vs Genome)P-Value (FDR Corrected)Genes
GeneDescriptionAvg. edge score to queryRankIn genesetIn query
GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
ADCY2adenylate cyclase 2 (brain)
GRM7glutamate receptor, metabotropic 7
SSTR2somatostatin receptor 2
APLP1amyloid beta (A4) precursor-like protein 1
Query geneGeneGene descriptionEdge score
GABBR2GABBR2gamma-aminobutyric acid (GABA) B receptor, 2
ADCY2ADCY2adenylate cyclase 2 (brain)
GRM7GRM7glutamate receptor, metabotropic 7
SSTR2SSTR2somatostatin receptor 2
APLP1APLP1amyloid beta (A4) precursor-like protein 1